Zobrazeno 1 - 10
of 385
pro vyhledávání: '"J. Hollmann"'
Autor:
Nathaniel Aleynick, Yanyun Li, Yubin Xie, Mianlei Zhang, Andrew Posner, Lev Roshal, Dana Pe’er, Rami S. Vanguri, Travis J. Hollmann
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-6 (2023)
Abstract Defining cellular and subcellular structures in images, referred to as cell segmentation, is an outstanding obstacle to scalable single-cell analysis of multiplex imaging data. While advances in machine learning-based segmentation have led t
Externí odkaz:
https://doaj.org/article/5c9f34089ca0498f9702599144084066
Autor:
Rebecca Caeser, Jacklynn V. Egger, Shweta Chavan, Nicholas D. Socci, Caitlin Byrne Jones, Faruk Erdem Kombak, Marina Asher, Michael H. Roehrl, Nisargbhai S. Shah, Viola Allaj, Parvathy Manoj, Sam E. Tischfield, Amanda Kulick, Maximiliano Meneses, Christine A. Iacobuzio-Donahue, W. Victoria Lai, Umeshkumar Bhanot, Marina K. Baine, Natasha Rekhtman, Travis J. Hollmann, Elisa de Stanchina, John T. Poirier, Charles M. Rudin, Triparna Sen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Creating accurate models of small cell lung cancer is essential to ensure the clinical relevance of results. Here, the authors create patient derived xenograft models from 33 patients and show, through multi-omics sequencing, that these models retain
Externí odkaz:
https://doaj.org/article/6db844e570e04ea595ba52c8f6bba923
Autor:
Brendan John Guercio, Gopa Iyer, Wajih Zaheer Kidwai, Mario E. Lacouture, Soleen Ghafoor, Anthony M. Rossi, David N. Assis, Ying-Bei Chen, Klaus J. Busam, Yelena Y. Janjigian, Komal Jhaveri, Darren R. Feldman, Anne Capozzi, Vanessa Figueroa, Dean F. Bajorin, Jonathan E. Rosenberg, Travis J. Hollmann, Samuel A. Funt
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 430-438 (2021)
Metastatic primary cutaneous extramammary Paget disease (EMPD) is a rare clinical entity with a 5-year survival
Externí odkaz:
https://doaj.org/article/d76cb10bfe2348a4802b4d6e377656f7
Understanding the impact of chemotherapy on the immune landscape of high-grade serous ovarian cancer
Autor:
Rami Vanguri, Jamal Benhamida, Jonathan H. Young, Yanyun Li, Oliver Zivanovic, Dennis Chi, Alexandra Snyder, Travis J. Hollmann, Katherine L. Mager
Publikováno v:
Gynecologic Oncology Reports, Vol 39, Iss , Pp 100926- (2022)
Objectives: We quantitatively characterized the change in temporospatial expression of repressive and stimulatory checkpoints across immune cell populations in the tumor microenvironment in a cohort of high grade serous ovarian carcinomas (HGSOC) usi
Externí odkaz:
https://doaj.org/article/aca89ed109ab4ad5b29c290f13a08bce
Autor:
Antoni Ribas, Paul Chapman, Katherine S Panageas, Michael Postow, Joyson Karakunnel, Hussein Tawbi, Christine Spencer, Katy Tsai, Ramy Ibrahim, Jedd Wolchok, Theresa LaVallee, Travis J Hollmann, Alexander Shoushtari, Daniel K Wells, Margaret Callahan, Samantha Bucktrout, Claire F Friedman, Christopher R Cabanski, Pier Gherardini, Richard O Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/53029230391949998c537d2be9d8cb9c
Publikováno v:
Cancer Discovery. 13:824-828
Summary: The shift in cancer therapy from broadly cytotoxic agents toward “personalized” treatments that target specific alterations in each patient's tumor requires diagnostic pathology approaches that are quantitative and biospecimen-friendly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a163f352968a5e4a474e12eaeb94353
https://doi.org/10.1158/2159-8290.cd-22-1015
https://doi.org/10.1158/2159-8290.cd-22-1015
Autor:
Dmitriy Zamarin, Siqing Fu, Elad Sharon, Travis J Hollmann, Alexia Iasonos, Jason A Konner, Susan C Modesitt, Qin Zhou, Alexandre Buckley De Meritens, Carol Aghajanian, Claire F Friedman, Panagiotis A Konstantinopoulos, Bradley R Corr, Michael A Carducci, Alexandra Snyder Charen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background There are limited treatment options for patients with metastatic or recurrent cervical cancer. Platinum-based chemotherapy plus the anti-vascular endothelial growth factor antibody bevacizumab remains the mainstay of advanced treatment. Pe
Externí odkaz:
https://doaj.org/article/b00b2e23c61f4db3a9c932d35221b118
Autor:
Dmitriy Zamarin, Taha Merghoub, Yanyun Li, Travis J Hollmann, Jason A Konner, Qin Zhou, Carol Aghajanian, Roisin E O’Cearbhaill, Aliya Holland, Rachel N Grisham, Keith L Knutson, Sven Walderich, Alexia E Iasonos, Jean M Torrisi, Lewis F Chesebrough, Autumn S Mcdonnell, Jacqueline M Gallagher, Courtney L Erskine
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Immune checkpoint inhibitors (ICIs) to date have demonstrated limited activity in advanced ovarian cancer (OC). Folate receptor alpha (FRα) is overexpressed in the majority of OCs and presents an attractive target for a combination immuno
Externí odkaz:
https://doaj.org/article/0a9f8241fd3942feb6d693998c7629aa
Autor:
Ignacio I Wistuba, Michael T Tetzlaff, Carlo B Bifulco, Katharina von Loga, Sacha Gnjatic, Scott J Rodig, Janis M Taube, Keith E Steele, Marlon C Rebelatto, David L Rimm, Ana Lako, Edwin R Parra, Guray Akturk, Michael Angelo, Elizabeth L Engle, Shirley Greenbaum, Noah F Greenwald, Cyrus V Hedvat, Travis J Hollmann, Jonathan Juco, Jaime Rodriguez-Canales, Kurt A Schalper, Edward C Stack, Cláudia S Ferreira, Konstanty Korski, Emanuel Schenck, Michael J Surace
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Objectives The interaction between the immune system and tumor cells is an important feature for the prognosis and treatment of cancer. Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) analyses are emerging technologies th
Externí odkaz:
https://doaj.org/article/aa359e762b4f41ddb084a9f360b5fc80
Autor:
Alyce M. Kuo, Hani Hassoun, Urvi Shah, Allison Gordon, Travis J. Hollmann, Heather J. Landau, Cecilia Lezcano, Sham Mailankody, Carlyn C. Tan, Alexander M. Lesokhin, Alina Markova
Publikováno v:
Leukemialymphoma. 63(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e9ee5dd7e5d7772746357d0d831590
https://pubmed.ncbi.nlm.nih.gov/35532206
https://pubmed.ncbi.nlm.nih.gov/35532206