Zobrazeno 1 - 10
of 204
pro vyhledávání: '"J. Hollingworth"'
Autor:
Manuel Pérez-Soto, Pablo Peñalver, Steven T.G. Street, Dora Weenink, Michael P. O'Hagan, Javier Ramos-Soriano, Y. Jennifer Jiang, Gregory J. Hollingworth, M. Carmen Galan, Juan C. Morales
Publikováno v:
Pérez-Soto, M, Peñalver, P, Street, S T G, Weenink, D, O'Hagan, M P, Ramos-Soriano, J, Jiang, Y J, Hollingworth, G J, Galan, M C & Morales, J C 2022, ' Structure-activity relationship studies on divalent naphthalene diimide G quadruplex ligands with anticancer and antiparasitic activity ', Bioorganic & Medicinal Chemistry, vol. 71, 116946 . https://doi.org/10.1016/j.bmc.2022.116946
Naphthalene diimide (NDI) is a central scaffold that has been commonly used in the design of G-quadruplex (G4) ligands. Previous work revealed notable anticancer activity of a disubstituted N-methylpiperazine propyl NDI G4 ligand. Here, we explored s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b98fb7e677ed04b99769a10d2f5408
https://research-information.bris.ac.uk/ws/files/334603680/Full_text_PDF_final_published_version_.pdf
https://research-information.bris.ac.uk/ws/files/334603680/Full_text_PDF_final_published_version_.pdf
Autor:
Hacer, Karatas, Tamara, Maric, Pier Luca, D'Alessandro, Aleksey, Yevtodiyenko, Thomas, Vorherr, Gregory J, Hollingworth, Elena A, Goun
Publikováno v:
ACS chemical biology. 14(10)
Peptides constitute an important class of drugs for the treatment of multiple metabolic, oncological, and neurodegenerative diseases, and several hundred novel therapeutic peptides are currently in the preclinical and clinical stages of development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c4a04b6c2202e5b6b48d85b5667cb86
https://pubmed.ncbi.nlm.nih.gov/31498986
https://pubmed.ncbi.nlm.nih.gov/31498986
Autor:
Jason Hilton, Alan R.T. Spencer, Gar W. Rothwell, Andrew R. Rees, Robert J. Raine, Russell J. Garwood, Neville T. J. Hollingworth
Publikováno v:
Spencer, A R T, Garwood, R, Rees, A R, Raine, R J, Rothwell, G W, Hollingworth, N T J & Hilton, J 2017, ' New insights into Mesozoic cycad evolution : an exploration of anatomically preserved Cycadaceae seeds from the Jurassic Oxford Clay biota ', PeerJ . https://doi.org/10.7717/peerj.3723
PeerJ
PeerJ, Vol 5, p e3723 (2017)
PeerJ
PeerJ, Vol 5, p e3723 (2017)
Most knowledge concerning Mesozoic Era floras has come from compression fossils. This has been augmented in the last 20 years by rarer permineralized material showing cellular preservation. Here, we describe a new genus of anatomically preserved gymn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d8a531d327e579b26765cd85204b77
http://hdl.handle.net/10044/1/50557
http://hdl.handle.net/10044/1/50557
Publikováno v:
International Journal of Coal Geology. 69:55-67
Discovery of a permineralized fossil cone in Mesozoic deposits of southern England provides an opportunity to document the first detailed evidence of internal pollen cone anatomy for the extinct conifer family Cheirolepidiaceae. The specimen, describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d891729b65d1c111322afc37dc3cd7b1
https://doi.org/10.1016/j.coal.2006.03.008
https://doi.org/10.1016/j.coal.2006.03.008
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 554:266-285
A Micromegas micro pattern charge readout device has been operated at room temperature in Argon and Xenon from 1 to 3.5 atm and also within the saturated vapour phase of a double-phase Xenon target. The dependence of the gain on the amplification fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa6fea7f1022d38a6505a53d36327a2
https://doi.org/10.1016/j.nima.2005.08.038
https://doi.org/10.1016/j.nima.2005.08.038
Autor:
J. J. Quenby, M. Gold, V. N. Lebedenko, T. Gamble, J. E. McMillan, S. Burgos, J. Turk, D. Loomba, N. Sanghi, Sean Paling, A. Petkov, G.G. Nicklin, A. Murphy, T. B. Lawson, M. Garcia, B. Morgan, E. J. Daw, P. K. Lightfoot, A. S. Howard, N. J. C. Spooner, S.J.S. Plank, E. Tziaferi, N. J. T. Smith, S. Hollen, M. J. Carson, A. Bewick, Daniel Tovey, R. Lüscher, J.C. Davies, T. J. Sumner, Daniel P. Snowden-Ifft, P.F. Smith, M. Robinson, V. A. Kudryavtsev, I. Liubarsky, J. Forbes, Rodney Walker, J.D. Lewin, G. J. Alner, J. Kirkpatrick, D. Muna, R. M. Preece, R. J. Hollingworth, C. Ghag, J. V. Dawson, Henrique Araujo
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 555:173-183
DRIFT-II is a second generation multi-module gaseous dark matter detector. Each module contains two time projection chambers positioned back-to-back inside a stainless steel vacuum vessel containing carbon disulphide gas. This paper describes the DRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea6c5c19c9a113eeb51a0732c5f9384
https://doi.org/10.1016/j.nima.2005.09.011
https://doi.org/10.1016/j.nima.2005.09.011
Autor:
E. A. Seddon, A. K. Mallick, S. V. Shiryaev, G. L. Bychkov, D. Tsoutsou, Phillip Sprunger, Andrew G. Thomas, J. Hollingworth, Sergei N. Barilo, R. L. Stockbauer, Richard L. Kurtz, Wendy R. Flavell, S. Patel
Publikováno v:
Journal of Electron Spectroscopy and Related Phenomena. :777-782
We discuss the use of resonant photoemission in the study of rare earth/transition metal perovskites and perovskite-related structures. We illustrate its application to the assignment of the RE and TM valence band density of states in Nd 2 Ni 1− x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bacf406e00f68531fc61f45488267c83
https://doi.org/10.1016/j.elspec.2005.01.149
https://doi.org/10.1016/j.elspec.2005.01.149
Autor:
S. M. Paling, D. C. R. Davidge, Gavin Davies, J.D. Lewin, T. Gamble, T. B. Lawson, J.C. Davies, A. Nicholls, G. J. Alner, G.T.J. Arnison, N. J. C. Spooner, T. J. Sumner, R. Lüscher, N. J. T. Smith, A. Bewick, M. J. Carson, S. P. Hart, A. S. Howard, G.G. Nicklin, P. K. Lightfoot, Daniel Tovey, J.W. Roberts, J. V. Dawson, G.J. Homer, B. Morgan, I. Ivaniouchenkov, Matthew J. Lehner, Henrique Araujo, J. E. McMillan, M. K. Joshi, R. J. Hollingworth, J.C. Barton, J. J. Quenby, R. M. Preece, T. Durkin, M. Robinson, C. Bungau, W. G. Jones, P.F. Smith, V. A. Kudryavtsev, V. N. Lebedenko, B. Camanzi, I. Liubarsky
Publikováno v:
New Astronomy Reviews. 49:245-249
The ZEPLIN I detector is a zero field liquid xenon detector used in the direct search for Galactic WIMP dark matter and has been operated at 2800 mwe depth in the Boulby mine underground facility in the UK. Discrimination between the types of interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e16db3243359f1ba26737bb5261f97
https://doi.org/10.1016/j.newar.2005.01.045
https://doi.org/10.1016/j.newar.2005.01.045
Publikováno v:
Journal of Clinical Pathology. 58:308-312
Background: CA125 is a high molecular weight glycoprotein, which is expressed by a large proportion of epithelial ovarian cancers. The sensitivity and specificity of CA125 are poor and there are no guidelines produced by the Royal College of Patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b13e9993936ead50c96b4c38743babc
https://doi.org/10.1136/jcp.2004.018077
https://doi.org/10.1136/jcp.2004.018077
Publikováno v:
Palaeontology. 47:1159-1180
An exceptionally well-preserved fauna from a new exposure in the Peterborough Member (Oxford Clay Formation) of southern England, equivalent to the famous and now inaccessible Lagerstatte at Christian Malford, Wiltshire, is described. It comes from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e669443f8fb34cf4532da9defb03f676
https://doi.org/10.1111/j.0031-0239.2004.00405.x
https://doi.org/10.1111/j.0031-0239.2004.00405.x