Zobrazeno 1 - 10
of 744
pro vyhledávání: '"J. Heng"'
Autor:
Yujing J. Heng, Gabrielle M. Baker, Valerie J. Fein-Zachary, Yaileen D. Guzman-Arocho, Vanessa C. Bret-Mounet, Erica S. Massicott, Vanda F. Torous, Stuart J. Schnitt, Sy Gitin, Paul Russo, Adam M. Tobias, Richard A. Bartlett, Gopal Varma, Despina Kontos, Lusine Yaghjyan, Michael S. Irwig, Jennifer E. Potter, Gerburg M. Wulf
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background The effect of gender-affirming testosterone therapy (TT) on breast cancer risk is unclear. This study investigated the association between TT and breast tissue composition and breast tissue density in trans masculine individuals (
Externí odkaz:
https://doaj.org/article/6fadfe83e91c42a2b3f583dd12169e41
Autor:
Alexandra R. Harris, Tengteng Wang, Yujing J. Heng, Gabrielle M. Baker, Phuong Anh Le, Jun Wang, Christine Ambrosone, Adam Brufsky, Fergus J. Couch, Francesmary Modugno, Christopher G. Scott, Celine M. Vachon, Susan E. Hankinson, Bernard A. Rosner, Rulla M. Tamimi, Cheng Peng, A. Heather Eliassen
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Early menarche is an established risk factor for breast cancer but its molecular contribution to tumor biology and prognosis remains unclear. Methods We profiled transcriptome-wide gene expression in breast tumors (N = 846) and tu
Externí odkaz:
https://doaj.org/article/76b5bacfbc8949afa92769f09a2daa34
Autor:
Shizhong Ke, Fabin Dang, Lin Wang, Jia-Yun Chen, Mandar T. Naik, Wenxue Li, Abhishek Thavamani, Nami Kim, Nandita M. Naik, Huaxiu Sui, Wei Tang, Chenxi Qiu, Kazuhiro Koikawa, Felipe Batalini, Emily Stern Gatof, Daniela Arango Isaza, Jaymin M. Patel, Xiaodong Wang, John G. Clohessy, Yujing J. Heng, Galit Lahav, Yansheng Liu, Nathanael S. Gray, Xiao Zhen Zhou, Wenyi Wei, Gerburg M. Wulf, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Induced oncoproteins degradation provides an attractive anti-cancer modality. Activation of anaphase-promoting complex (APC/CCDH1) prevents cell-cycle entry by targeting crucial mitotic proteins for degradation. Phosphorylation of its co-act
Externí odkaz:
https://doaj.org/article/0b6bab263e5b452fb61f77b6a5e52d6a
Autor:
Yujing J. Heng, Kevin J. Zhang, Monica G. Valero, Gabrielle M. Baker, Valerie J. Fein-Zachary, Michael S. Irwig, Gerburg M. Wulf
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 811-817 (2023)
There is limited literature about breast cancer in the transgender population. Very little is known about how gender-affirming hormone therapy affects their breast cancer risk. On the other end, for those diagnosed with breast cancer, there are no cl
Externí odkaz:
https://doaj.org/article/08bcef7ebd2f43bca0a992f0593b67b9
Autor:
Lusine Yaghjyan, Yujing J. Heng, Gabrielle M. Baker, Vanessa C. Bret-Mounet, Divya Murthy, Matt B. Mahoney, Bernard Rosner, Rulla M. Tamimi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundWe investigated the associations of reproductive factors known to influence breast cancer risk with the expression of breast stem cell markers CD44, CD24, and ALDH1A1 in benign breast biopsy samples.MethodsWe included 439 cancer-free women
Externí odkaz:
https://doaj.org/article/5734fc4396d34b45a14cdcb107f8963a
Autor:
Jonathan D. Lee, Bridget L. Menasche, Maria Mavrikaki, Madison M. Uyemura, Su Min Hong, Nina Kozlova, Jin Wei, Mia M. Alfajaro, Renata B. Filler, Arne Müller, Tanvi Saxena, Ryan R. Posey, Priscilla Cheung, Taru Muranen, Yujing J. Heng, Joao A. Paulo, Craig B. Wilen, Frank J. Slack
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113478- (2023)
Summary: Coronavirus disease 2019 (COVID-19) remains a significant public health threat due to the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants to evade the immune system and cause breakthrough infections. Although
Externí odkaz:
https://doaj.org/article/fc5e40c8967549f19441624446c62419
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background We investigated the associations of alcohol with percentage of epithelium, stroma, fibroglandular tissue (epithelium + stroma), and fat in benign breast biopsy samples. Methods We included 857 cancer-free women with biopsy-confirm
Externí odkaz:
https://doaj.org/article/b3541dc7e66e4001967098f26cf255e3
Autor:
Sarah Asad, Adrienne Damicis, Yujing J. Heng, Kathryn Kananen, Katharine A. Collier, Elizabeth J. Adams, Kevin H. Kensler, Gabrielle M. Baker, Robert Wesolowski, Sagar Sardesai, Margaret Gatti-Mays, Bhuvaneswari Ramaswamy, A. Heather Eliassen, Susan E. Hankinson, Fred K. Tabung, Rulla M. Tamimi, Daniel G. Stover
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Background Breast tumor immune infiltration is clearly associated with improved treatment response and outcomes in breast cancer. However, modifiable patient factors associated with breast cancer immune infiltrates are poorly understood. The
Externí odkaz:
https://doaj.org/article/bfd391b7b4c543cc8e9f6b20a3f6dcf9
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background The mutational profile of cancer reflects the activity of the mutagenic processes which have been operative throughout the lineage of the cancer cell. These processes leave characteristic profiles of somatic mutations called mutat
Externí odkaz:
https://doaj.org/article/31efe95b91134ea5bd40e4797f7cb13a
Autor:
Lusine Yaghjyan, Yujing J. Heng, Gabrielle M. Baker, Vanessa Bret-Mounet, Divya Murthy, Matt B. Mahoney, Yi Mu, Bernard Rosner, Rulla M. Tamimi
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundThe data on the expression of stem cell markers CD44, CD24, and ALDH1A1 in the breast tissue of cancer-free women is very limited and no previous studies have explored the agreement between pathologist and computational assessments of these
Externí odkaz:
https://doaj.org/article/83f00cf54bf84fb0ae4b6aa0de4da47f