Zobrazeno 1 - 10
of 56
pro vyhledávání: '"J. Hempenius"'
Publikováno v:
Blood pressure. 9(sup1)
Variability of blood pressure responses to inhibition of the renin-angiotensin system is influenced by factors inherent in the patient, such as renin status, and by drug-specific factors, such as pharmacokinetics. The pharmacokinetic-pharmacodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a71ed5b1acdb9e47597c94df9535f37
https://pubmed.ncbi.nlm.nih.gov/28425793
https://pubmed.ncbi.nlm.nih.gov/28425793
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 714:361-368
For the implementation and validation of an automated `high-throughput' solid-phase extraction (SPE) system, using microtiter solid-phase technology and a pipetting robot, a SPE method previously validated manually for cimetidine in human plasma was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1737ae46f35129e622829c2983d60f0
https://doi.org/10.1016/s0378-4347(98)00232-1
https://doi.org/10.1016/s0378-4347(98)00232-1
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 25:355-366
The liquid—liquid extraction of tricyclic amines (antidepressants) was optimised using mixture experimental designs, the physical part of which was performed by a laboratory robotic system. This system was controlled and directed by a second, exter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01cb23fb05cd9736de20a718294b7fe7
https://doi.org/10.1016/0169-7439(94)85053-4
https://doi.org/10.1016/0169-7439(94)85053-4
Publikováno v:
Journal of Chromatography A. 545:101-114
For the optimization of the reversed-phase high-performance liquid chromatographic separation of twelve sulphonamides using a quaternary mobile phase, quadratic regression models were calculated. The three pseudo-components were buffer-methanol, buff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3ea44ce5d05f7b1a9e894b46f8f838
https://doi.org/10.1016/s0021-9673(01)88699-4
https://doi.org/10.1016/s0021-9673(01)88699-4
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 8:577-582
The application of fully automated, unattended sample preparation performed by a laboratory robot for the analysis of drugs in biological samples requires the prevention of system failures which may arise in the on-line coupled chromatographic system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ae4c8ced624c528770ea54215018f4
https://doi.org/10.1016/0731-7085(90)80083-2
https://doi.org/10.1016/0731-7085(90)80083-2
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 20(6)
A quantitative method for the analysis of haloperidol in human plasma is described. Sample clean-up was performed by means of solid-phase extraction using 3M Empore™ extraction disk plates in the 96-well format, automated with a Canberra Packard pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565d715809b49d978f9a032dc4c72ea4
https://pubmed.ncbi.nlm.nih.gov/10746957
https://pubmed.ncbi.nlm.nih.gov/10746957
Autor:
J. Hempenius, W.J Tamminga, J. Wieling, B. Oosterhuis, G. Hendriks, C.K. Mensink, Jan H.G. Jonkman
Publikováno v:
Journal of chromatography. A. 730(1-2)
Generally, bioanalytical chromographic methods are validated according to a predefined programme and distinguish a pre-validation phase, a main validation phase and a follow-up validation phase. In this paper, a rational, total performance evaluation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfed3680a07ae64b8457f7d767131464
https://pubmed.ncbi.nlm.nih.gov/8680594
https://pubmed.ncbi.nlm.nih.gov/8680594
Autor:
B, Oosterhuis, M D, Brannan, H, Groen, P A, Peeters, J, Hempenius, E, Radwanski, A A, Nomeir, M B, Affrime, J H, Jonkman
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 75(2)
There is a close relationship between improvement in airway function and the plasma concentration of theophylline, as well as between rapidly rising plasma theophylline concentrations and increased frequency of undesired effects. Development of pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26ff3280181741655f3d55467e5dc127
https://pubmed.ncbi.nlm.nih.gov/7648380
https://pubmed.ncbi.nlm.nih.gov/7648380
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 12(11)
An automated analytical method for the determination of felbamate in human plasma is described. Sample cleanup and preparation was performed by means of a Zymate II laboratory robot and consisted of a liquid-liquid extraction of felbamate and the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890384522e1c245c9941c4c255054ead
https://pubmed.ncbi.nlm.nih.gov/7849139
https://pubmed.ncbi.nlm.nih.gov/7849139
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 8(4)
The quality of bioanalytical methods is often determined by the quality of sample preparation. Using a robot for sample treatment may give better results than manual sample preparation, since the robot lacks human behaviour and incidental errors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6371a1ae04550145d630f207c388ce5
https://pubmed.ncbi.nlm.nih.gov/2100205
https://pubmed.ncbi.nlm.nih.gov/2100205