Výsledky vyhledávání - "J. Harmenberg"

Herpes simplex virus type 1 infection and glucocorticoid treatment regulate viral yield, glucocorticoid receptor and NF-kappaB levels

Autor: Anna Erlandsson, J Harmenberg, Pontus Stierna, O Hammarsten, T Yucel-Lindberg, LG Bladh, Ann-Charlotte Wikström, T Modeer

Publikováno v: Karolinska Institutet

The interplay between the endocrine and immune systems has come into focus in recent years with the insight that endocrine parameters may affect susceptibility to both auto-immune and infectious diseases. Our interest in immunoendocrine regulation le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8d13c4f303ea21f9ebe92a890cf8e7
https://doi.org/10.1677/joe.0.1750165

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Synergistic inhibition of human immunodeficiency virus isolates (including 3'-azido-3'-deoxythymidine-resistant isolates) by foscarnet in combination with 2',3'-dideoxyinosine or 2',3'-dideoxycytidine

Autor: Susan Cox, Sarah Palmer, J. Harmenberg

Publikováno v: Antimicrobial Agents and Chemotherapy. 40:1285-1288

The combinations of foscarnet plus 2',3'-dideoxyinosine and foscarnet plus 2',3'-dideoxycytidine synergistically inhibit the replication of human immunodeficiency virus type 1 isolates, including two 3'-azido-3'-deoxythymidine-resistant isolates. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c0a96a5c2d77ebb014672f8385aac4
https://doi.org/10.1128/aac.40.5.1285

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Intracellular Metabolism of 3′-Azido-3′-Deoxythymidine in the Presence of Ganciclovir or Foscarnet

Autor: Susan Cox, H. Rasmussen, J. Harmenberg, Sarah Palmer

Publikováno v: Antiviral Chemistry and Chemotherapy. 7:14-20

Comparisons were made between the intracellular phosphorylation of 3′-Azido-3′-deoxythymidine (AZT) alone and in combination with ganciclovir (GCV) or foscarnet (PFA) in lymphocytes, uninfected fibroblasts and CMV-infected fibroblasts. The effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::272e43fd14d61ddbcb5f3e9218a31c75
https://doi.org/10.1177/095632029600700103

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Antiviral Activity against VZV and HSV Type 1 and Type 2 of the (+) and (−) Enantiomers of (R,S)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine, in Comparison to other Closely Related Acyclic Nucleosides

Autor: A. Karlström, Susan Cox, Britta Wahren, G. Abele, B. Lindborg, S. Bergman, J. Harmenberg, A. Vissgården

Publikováno v: Antiviral Chemistry and Chemotherapy. 2:163-169

The separate (+) and (−) enantiomers of the acyclic guanosine analogue 9-[4-hydroxy-2-(hydroxymethyl)-butyl]guanine (2HM-HBG) were tested for inhibition of varicella-zoster virus (VZV), herpes simplex virus type 1 (HSV-1) and herpes simplex virus t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe6cb28f20950df14b055b486064b0b6
https://doi.org/10.1177/095632029100200306

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Comparison of the Mechanism of Toxicity of 3′-Azido-3′-Deoxythymidine and 3′-Fluoro-3′-Deoxythymidine in Human Lymphocytes

Autor: Susan Cox, J. Harmenberg

Publikováno v: Antiviral Chemistry and Chemotherapy. 1:269-277

The thymidine analogue 3′-azido-3′-deoxythymidine (AZT), whilst a useful drug for the treatment of acquired immunodeficiency syndrome, produces toxic side-effects which can be severe and can interfere with therapy. The toxic mechanism of AZT is u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8102aeeb7fd344a9416a25030d52973e
https://doi.org/10.1177/095632029000100407

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Antiviral activity of low-dose alovudine in antiretroviral-experienced patients: results from a 4-week randomized, double-blind, placebo-controlled dose-ranging trial

Autor: Hernan Valdez, ND Sabo, A-M Quinson, Laurent Cotte, Douglas L. Mayers, M-L Bravo, C Piketty, Jade Ghosn, J Harmenberg, G Mårdh, N Dorléacq, Christine Katlama

Publikováno v: HIV medicine. 8(3)

Background Alovudine inhibits replication of highly nucleoside reverse transcriptase inhibitor (NRTI)-resistant HIV strains in vitro. However, dose-dependent safety concerns resulted in its initial development being halted. Recently, a 4-week course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456384cc75b7d0a60db0551dc06aae2d
https://pubmed.ncbi.nlm.nih.gov/17461857

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