Addressing child undernutrition in Tanzania with the ASTUTE program

Autor: E Beckstead, G Mulokozi, M Jensen, J Smith, M Baldauf, K. A. Dearden, M. Linehan, S. Torres, J. Glenn, J. H. West, P. C. Hall, B. T. Crookston

Publikováno v: BMC Nutrition, Vol 8, Iss 1, Pp 1-11 (2022)

Abstract Background Optimal infant and young child feeding practices (IYCFP) reduce childhood stunting and are associated with additional health benefits. In Tanzania, IYCFP are far from optimal where 32% of children under the age of 5 years are stun

Externí odkaz: https://doaj.org/article/1a12f99deb8f4b638b13981a9ec0e218

Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

Autor: Ryan J. H. West, Joanne L. Sharpe, André Voelzmann, Anna L. Munro, Ines Hahn, Richard A. Baines, Stuart Pickering-Brown

Publikováno v: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)

Abstract A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Disease (MND). In patients this exp

Externí odkaz: https://doaj.org/article/4e9a52c5a5ea4a479ca7cd7829ad0e49

Modeling

Autor: Joanne L, Sharpe, Nikki S, Harper, Duncan R, Garner, Ryan J H, West

Publikováno v: Frontiers in Cellular Neuroscience

An intronic hexanucleotide (GGGGCC) expansion in the C9orf72 gene is the most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). In the decade following its discovery, much progress has been made in enhanci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0321299a8a1fde30ebc0ff5c09a3781
https://pubmed.ncbi.nlm.nih.gov/34744635

Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

Autor: Anna L. Munro, Ines Hahn, Ryan J. H. West, Stuart Pickering-Brown, Richard A. Baines, Joanne L. Sharpe, André Voelzmann

Publikováno v: Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Hahn, I, Sharpe, J, Voelzmann, A, Munro, A, Baines, R, Pickering-Brown, S & West, R 2020, ' Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-and combination-specific phenotypic profiles in Drosophila ', Acta Neuropathologica Communications, vol. 8, no. 158 . https://doi.org/10.1186/s40478-020-01028-y

A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Disease (MND). In patients this expansion is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d42ac9e36c8afe30209b02288df1ed
http://europepmc.org/articles/PMC7487709

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

Autor: Ryan J. H. West, Khomgrit Morarach, Matthias Landgraf, Matthew C. W. Oswald, Maarten Zwart, Paul S Brooks, Richard A. Baines, Carlo N.G. Giachello, Sean T. Sweeney, Amrita Mukherjee

Publikováno v: Oswald, M C W, Brooks, P S, Zwart, M F, Mukherjee, A, West, R J H, Giachello, C N G, Morarach, K, Baines, R A, Sweeney, S T & Landgraf, M 2018, ' Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila ', eLife, vol. 7, e39393 . https://doi.org/10.7554/eLife.39393
eLife, Vol 7 (2018)
eLife

Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the nervous system under non-pathological conditions has remained poorly understood. Working with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0acee3003e81ad0d77721c876988d0
https://www.repository.cam.ac.uk/handle/1810/289769