Výsledky vyhledávání - "J. H. Scarffe"

VAD chemotherapy—toxicity and efficacy—in patients with multiple myeloma and other lymphoid malignancies

Autor: M. Lambert, C. C. Chan, G Chadwick, J. H. Scarffe, David B. Smith, James Chang, Derek Crowther, Ric Swindell, A. McMahon, Heather Anderson

Publikováno v: Hematological Oncology. 5:213-222

Thirty-three patients with multiple myeloma (11 untreated, 15 refractory and seven relapsed patients) have received vincristine and adriamycin infusion therapy with oral dexamethasone (VAD). The median number of courses received was five. In addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24a1b29981244c66bc44a9b5135274b
https://doi.org/10.1002/hon.2900050308

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Prospective evaluation of oral mucositis in patients receiving myeloablative conditioning regimens and haemopoietic progenitor rescue

Autor: Gordon C Jayson, R. Bloor, G. R. Morgenstern, Ric Swindell, James Chang, C.J. Fraser, Andrew M Wardley, J. H. Scarffe

Publikováno v: British Journal of Haematology. 110:292-299

Four hundred and twenty-nine patients received myeloablative chemotherapy for solid and haematological malignancies in a bone marrow transplantation unit. Regimens appropriate to the tumour type were administered and haemopoietic reconstitution was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e4e0d017d4018c089554ec66323231b
https://doi.org/10.1046/j.1365-2141.2000.02202.x

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Immunogenicity of vaccination against influenza, Streptococcus pneumoniae and Haemophilus influenzae type B in patients with multiple myeloma

Autor: J. H. Scarffe, Mark Dougal, Heather Anderson, J D Robertson, M Zambon, K Nagesh, S N Jowitt, K Mutton

Publikováno v: British Journal of Cancer

Vaccination against influenza and Streptococcus pneumoniae is recommended for elderly and immunocompromised individuals. However, there is little information concerning the efficacy of vaccination in specific groups of patients. In this study, 52 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba07e53d703fc7c54d70be425f02bc7
https://doi.org/10.1054/bjoc.1999.1088

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Content of long-term culture-initiating cells, clonogenic progenitors and CD34+cells in apheresis harvests of normal donors for allogeneic transplantation, and in patients with acute myeloid leukaemia or multiple myeloma

Autor: U. W. Schaefer, J. H. Scarffe, Dietrich W. Beelen, W. D. J. Ryder, Nydia G Testa, C. Kasper, J. Chang, Jan Dürig, K. Nagesh

Publikováno v: British Journal of Haematology. 104:374-381

Using a limiting dilution assay the frequency of long-term culture-initiating cells (LTC-IC) in the apheresis products following mobilization by granulocyte-colony stimulating factor (G-CSF) with or without chemotherapy from 14 normal donors (ND) for

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https://doi.org/10.1046/j.1365-2141.1999.01152.x

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Recombinant human granulocyte colony-stimulating factor (filgrastim) following high-dose chemotherapy and peripheral blood progenitor cell rescue in high-grade non-Hodgkin's lymphoma: clinical benefits at no extra cost

Autor: LS Dobson, G. R. Morgenstern, J. H. Scarffe, Derek Crowther, John Radford, W. D. J. Ryder, R. Pettengell, T. Huq, Siow Ming Lee

Publikováno v: University of Manchester-PURE
British Journal of Cancer

In order to evaluate the potential clinical and economic benefits of granulocyte colony-stimulating factor (G-CSF, filgrastim) following peripheral blood progenitor cells (PBPC) rescue after high-dose chemotherapy (HDCT), 23 consecutive patients aged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8bc3de8d4f03cda738d329b4b3b278
https://doi.org/10.1038/bjc.1998.216

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Autografting in Philadelphia (Ph)+ chronic myeloid leukaemia using cultured marrow: an update of a pilot study

Autor: M. L. Brereton, L. H. Coutinho, Nydia G Testa, S Burdach, G. R. Morgenstern, J. H. Scarffe, James Chang, JALiu Yin, Christine J. Harrison, PJ Darbyshire, T. M. Dexter

Publikováno v: Bone Marrow Transplantation. 19:969-976

Incubation of CML marrow in long-term culture (LTC) conditions may result in selection of normal (Ph-) LTC-initiating cells (LTC-IC) as early as 10 days, and in production of Ph- clonogenic cells and mature end cells within 5 weeks. This was the rati

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https://doi.org/10.1038/sj.bmt.1700777

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Treatment of inoperable hepatocellular carcinoma with pegylated liposomal doxorubicin (PLD): results of a phase II study

Autor: Janette Beech, Ric Swindell, David J Sherlock, Malcolm R Ranson, Adam Dangoor, Juan W. Valle, J H Scarffe, Siow Ming Lee

Publikováno v: British Journal of Cancer

Monthly intravenous pegylated liposomal doxorubicin (PLD) 50 mg m(-2), although well tolerated, showed almost no activity in this phase II study of 16 patients with advanced hepatocellular carcinoma with a response rate of 0%, stable disease 19%, med

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https://doi.org/10.1038/sj.bjc.6602394

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Epidemiology of an outbreak due to glycopeptide-resistant Enterococcus faecium on a leukaemia unit

Autor: J. H. Scarffe, P.R. Chadwick, A. Fox, G.R. Morgenstern, Neil Woodford, Beryl Oppenheim

Publikováno v: Journal of Hospital Infection. 34:171-182

The clinical and molecular epidemiology of two clusters of colonization and infection of patients by glycopeptide-resistant enterococci (GRE) on a leukaemia and bone marrow transplantation unit was studied over a two-and-a half-year period. Thirty-fi

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https://doi.org/10.1016/s0195-6701(96)90063-8

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VAD chemotherapy as remission induction for multiple myeloma

Autor: L Fitzsimmons, G. R. Morgenstern, D Ryder, Heather Anderson, J. H. Scarffe, GS Wieringa, Malcolm R Ranson, R.I. Young

Publikováno v: British Journal of Cancer

A total of 142 patients with multiple myeloma received VAD as remission induction therapy. Seventy-five were previously untreated and 67 had relapsed (31) or refractory disease (36). Vincristine (total dose 1.6 mg) was infused with doxorubicin 36 mg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc539a149366f6ada921f90018abb1b
https://doi.org/10.1038/bjc.1995.65

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Haemopoietic progenitor and myeloid cell kinetics in humans treated with interleukin-3 and granulocyte/macrophage colony-stimulating factor in combination

Autor: James Chang, L. H. Coutinho, Demuynck H, S. Bretti, J. H. Scarffe, L. Fitzsimmons, Nydia G Testa, de Campos E, Lord Bi

Publikováno v: International Journal of Cancer. 59:483-490

Patients with advanced adenocarcinoma of the colon, rectum or pancreas were entered into trials for evaluation of treatment with sequential doses of IL-3 and GM-CSF. They received 0.25 to 5 micrograms IL-3/kg/d for up to 7 days, followed by 1 microgr

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https://doi.org/10.1002/ijc.2910590409

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