Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. H. Ryan"'
Autor:
Guochang Huang, Andrew J Kaufman, Russell J H Ryan, Yevgeniy Romin, Laryssa Huryn, Sarina Bains, Katia Manova-Todorova, Patricia L Morris, Gary R Hunnicutt, Carrie A Adelman, John H J Petrini, Y Ramanathan, Bhuvanesh Singh
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209995 (2019)
Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members. Targeted inactivation of DCUN1D1 in mice results in male-specific i
Externí odkaz:
https://doaj.org/article/b2c5cb5ef6f94ce8bb3cf00f8422e4c2
Autor:
Shirish, Shukla, Weijiang, Ying, Felicia, Gray, Yiwu, Yao, Miranda L, Simes, Qingjie, Zhao, Hongzhi, Miao, Hyo Je, Cho, Paula, González-Alonso, Alyssa, Winkler, George, Lund, Trupta, Purohit, EunGi, Kim, Xiaotian, Zhang, Joshua M, Ray, Shihan, He, Caroline, Nikolaidis, Juliano, Ndoj, Jingya, Wang, Łukasz, Jaremko, Mariusz, Jaremko, Russell J H, Ryan, Monica L, Guzman, Jolanta, Grembecka, Tomasz, Cierpicki
Publikováno v:
Nature chemical biology. 17(7)
Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying complex that monoubiquitinates histone H2A and is involved in maintaining the repressed chromatin state. Emerging evidence suggests PRC1 activity in various cancers, rationalizi
Autor:
Russell J H Ryan, Mai Nitta, Darrell Borger, Lawrence R Zukerberg, Judith A Ferry, Nancy Lee Harris, A John Iafrate, Bradley E Bernstein, Aliyah R Sohani, Long Phi Le
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28585 (2011)
Mutations at codon 641 of EZH2 are recurrent in germinal center B cell lymphomas, and the most common variants lead to altered EZH2 enzymatic activity and enhanced tri-methylation of histone H3 at lysine 27, a repressive chromatin modification. As an
Externí odkaz:
https://doaj.org/article/bf516049533c48d780c32bc7b0f7af86
Autor:
Bhuvanesh Singh, Alexander Y. Kim, Guochang Huang, Andrew Kaufman, Bing Hao, Claire C. Bommeljé, Lydia Choi, Benjamin E. Lee, Yoshihiro Yonekawa, Russel J. H. Ryan, Y. Ramanathan, Luc G. T. Morris
Publikováno v:
Journal of Biological Chemistry, 283(48), 33211-33220. American Society for Biochemistry and Molecular Biology Inc.
Covalent modification of cullins by the ubiquitin-like protein NEDD8 (neddylation) regulates protein ubiquitination by promoting the assembly of cullin-RING ligase E3 complexes. Like ubiquitination, neddylation results from an enzymatic cascade invol
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Publikováno v:
The New England journal of medicine. 368(15)
Publikováno v:
The New England journal of medicine. 367(6)
Publikováno v:
Science (New York, N.Y.). 336(6088)
Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein
Publikováno v:
Journal of Virology. 68:4988-4997
We have used baculovirus-expressed Rep68 that has been purified to homogeneity to reexamine the binding properties of the Rep protein. We find that Rep68 is capable of binding to a linear DNA sequence that is contained within a 25-bp sequence of the
Autor:
Russell J H, Ryan, J Mark, Sloan, A Bernard, Collins, Jaleh, Mansouri, Noopur S, Raje, Lawrence R, Zukerberg, Judith A, Ferry
Publikováno v:
American journal of clinical pathology. 137(1)
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma is a mature B-cell neoplasm that typically follows an indolent clinical course. Amyloid deposition associated with MALT lymphoma is uncommon. We describe the clini