Zobrazeno 1 - 10
of 446
pro vyhledávání: '"J. H. Pringle"'
Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells
Autor:
W R, Wan Makhtar, G, Browne, A, Karountzos, C, Stevens, Y, Alghamdi, A R, Bottrill, S, Mistry, E, Smith, M, Bushel, J H, Pringle, A E, Sayan, E, Tulchinsky
Publikováno v:
Oncogene
Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execute EMT programs in embryonic development and cancer. By studying regulation of their expression, we describe a novel mechanism that limits ZEB2 protein s
Autor:
J. H. Pringle, Tom Brown, A. S. J. Stewart, Elaine M. Bailey, Catherine M. McKeen, S. J. Harper, John Feehally
AIM: To determine the optimum form of labelling and the most efficient reporter molecule for non-radioisotopic in situ hybridisation (ISH). METHODS: Nine deoxyoligonucleotides complementary to histone mRNA were synthesised and labelled either enzymat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb3fdc89d96d6227c1462f3d5ebdac1
https://doi.org/10.1136/jcp.50.8.686
https://doi.org/10.1136/jcp.50.8.686
Publikováno v:
British Journal of Surgery. 96:702-710
Background Recent studies have identified unique small ribonucleic acids called microRNAs (miRNAs) in colonic tumour tissue and blood that may accurately diagnose the presence of colorectal cancer and help predict disease recurrence. This review expl
Publikováno v:
International Journal of Experimental Pathology. 86:19-24
Apoptosis is implicated as a major pathogenic mechanism in chronic hepatitis B and C. Previous studies of the relationship between apoptotic rates and histological necroinflammatory activity have produced conflicting results. Hepatocyte apoptosis was
Publikováno v:
Journal of Clinical Pathology. 56:271-276
Smooth muscle actin (SMA) positive myofibroblasts have been implicated in tumour invasion; however, acquisition of SMA is not limited to peritumorous fibroblasts and other changes in fibroblasts may be more specifically related to the malignant envir
Publikováno v:
The Journal of Pathology. 201:562-572
In normal breast and ductal carcinoma in situ, myoepithelial cells form an incomplete layer separating the epithelial compartment from the stromal environment. Transition to invasive disease is marked by penetration of the myoepithelial-basement memb
Autor:
Druskovich C; College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA., Kelley J; Department of General Surgery, Corewell Health, Grand Rapids, Michigan, USA., Aubrey J; Department of General Surgery, Corewell Health, Grand Rapids, Michigan, USA., Palladino L; College of Literature, Science, and the Arts, University of Michigan, Ann Arbor, Michigan, USA., Wright GP; Department of Surgical Oncology, Corewell Health, Grand Rapids, Michigan, USA.
Publikováno v:
Journal of surgical oncology [J Surg Oncol] 2024 Oct 16. Date of Electronic Publication: 2024 Oct 16.
Autor:
Elaine M. Bailey, M J Bottomley, Steven J. Harper, John Feehally, Peter N. Furness, P. E. C. Brenchley, S Westwell, J. H. Pringle
Publikováno v:
ResearcherID
AIM: To investigate vascular endothelial growth factor (VEGF) mRNA expression in glomerular disease in the context of heavy proteinuria. METHODS: Non-radioisotopic in situ hybridisation was performed using a cocktail of 12 deoxyoligonucleotides compl
Publikováno v:
Nephrology Dialysis Transplantation. 14:1234-1237
the eVacement of foot processes represents a simpliBackground. Nephrin recently has been identified as a fication of architecture which demands massive remodputative adhesion molecule, expressed in the glomer- elling of the podocyte intercellular jun
Publikováno v:
Journal of Clinical Pathology. 50:553-558
AIMS: To visualise directly numerical chromosomal aberrations and polyploidy in both Hodgkin and Reed Sternberg (HRS) cells and background cells from cases of Hodgkin's disease using in situ hybridisation. METHODS: Non-isotopic DNA in situ hybridisat