Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J. H. Prehn"'
Autor:
M. Sturrock, I. S. Miller, G. Kang, N. Hannis Arba’ie, A. C. O’Farrell, A. Barat, G. Marston, P. L. Coletta, A. T. Byrne, J. H. Prehn
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/36e3b1ce77414480badc775d5dcd95e0
Publikováno v:
Journal of neurochemistry. 78(6)
During apoptotic and excitotoxic neuron death, challenged mitochondria release the pro-apoptotic factor cytochrome c. In the cytosol, cytochrome c is capable of binding to the apoptotic protease-activating factor-1 (APAF-1). This complex activates pr
Publikováno v:
The European journal of neuroscience. 10(5)
Excitotoxic mechanisms are believed to be involved in the death of neurons after trauma, epileptic seizures and cerebral ischaemia. We investigated the role of mitochondrial superoxide production in excitotoxic cell death of cultured rat hippocampal
Autor:
J H, Prehn, V P, Bindokas, J, Jordán, M F, Galindo, G D, Ghadge, R P, Roos, L H, Boise, C B, Thompson, S, Krajewski, J C, Reed, R J, Miller
Publikováno v:
Molecular pharmacology. 49(2)
Neurodegeneration associated with Alzheimer's disease is believed to involve toxicity to beta-amyloid (A beta) and related peptides. Treatment of cultured rat hippocampal neurons with A beta 1-40 (1 microM) or the active fragment A beta 25-35 (1 micr
Publikováno v:
Molecular pharmacology. 47(6)
Rat superior cervical ganglion neurons require the presence of nerve growth factor (NGF) to develop and survive in culture. If NGF is removed from the culture medium, then the neurons die of programmed cell death. We investigated the potential role o