Zobrazeno 1 - 10
of 72
pro vyhledávání: '"J. H. Healey"'
Autor:
J. H. Healey
Publikováno v:
LO SCALPELLO-OTODI Educational. 25:173-181
Basic science research holds the promise of rounds of discovery that will help to overcome treatment barriers for primary bone tumors. The management of primary bone sarcomas has achieved a consistently high level around the world. The growth and dev
Publikováno v:
Chinese medical journal. 112(12)
To analyse comparatively the relevant data from bone tumor registries in China, Japan, and the United States.The data of 38,959 histologically confirmed primary bone tumors collected by the Chinese Bone Tumor Registry 1957-1988, 20,272 collected by t
Autor:
R, Gorlick, A C, Liao, C, Antonescu, A G, Huvos, J H, Healey, R, Sowers, M, Daras, E, Calleja, L H, Wexler, D, Panicek, P A, Meyers, S D, Yeh, S M, Larson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(10)
In osteosarcoma, some studies have suggested P-glycoprotein expression is a prognostic factor. The clearance of (99m)technetium hexakis-2-methoxyisobutylisonitrile ((99m)Tc-MIBI) has been used in some tumor systems as an in vivo measure of P-glycopro
Autor:
C R, Antonescu, A, Elahi, M, Humphrey, M Y, Lui, J H, Healey, M F, Brennan, J M, Woodruff, S C, Jhanwar, M, Ladanyi
Publikováno v:
The Journal of molecular diagnostics : JMD. 2(3)
Myxoid liposarcoma (LS), the most common subtype of LS, is known to be characterized by the specific t(12;16) resulting in a TLS-CHOP fusion in almost all cases. We wished to address the following questions: (i) Is this genetic hallmark also present
Publikováno v:
The Journal of bone and joint surgery. British volume. 82(5)
We analysed the gait characteristics of 15 patients with prosthetic reconstruction of the proximal femur after resection of a malignant bone tumour using stride analysis and measurement of oxygen consumption. Compared with normal volunteers their gai
Autor:
C R, Antonescu, A, Elahi, J H, Healey, M F, Brennan, M Y, Lui, J, Lewis, S C, Jhanwar, J M, Woodruff, M, Ladanyi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(7)
Multifocal presentation, defined as the presence of tumor at two or more anatomically separate sites, before the manifestation of disease in sites where sarcomas usually metastasize (e.g., lungs) occurs in about 1% of extremity soft tissue sarcomas (
Publikováno v:
Cancer. 88(12)
Staging systems for soft tissue sarcoma (STS) are important to identify patients with similar systemic risk who might benefit from specific treatments. This study compared four commonly used staging systems for predicting systemic outcomes of patient
Publikováno v:
Medical and pediatric oncology. 33(2)
As an alternative to high-dose irradiation, limited surgery and low-dose irradiation have been investigated as a means to achieve local control. We retrospectively examined the clinical characteristics, treatment, and outcome for 25 patients with Ewi
Publikováno v:
Cancer research. 59(7)
The t(11;22)(q24;q12) translocation is present in up to 95% of cases of Ewing's sarcoma and results in the formation of an EWS-FLI1 fusion gene which encodes a chimeric transcription factor. The proximate role of EWS-FLI1 in the pathogenesis of Ewing
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(3)
High-dose methotrexate is a major component of current protocols for the treatment of osteosarcoma, but some tumors seem to be resistant. Potential mechanisms of resistance include decreased transport through the reduced folate carrier (RFC) and incr