Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J. H. Gerlach"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)
Previously (L. C. Young et al., Clin. Cancer Res., 5: 673-680, 1999), we found, in a panel of 23 lung cancer cell lines that had not been selected for in vitro drug resistance, that the mRNA levels of MRP3 and MRP1, two members of the ATP-binding cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db8bfdbdbd4db9770c8d598fe72b9ca7
https://pubmed.ncbi.nlm.nih.gov/11410522
https://pubmed.ncbi.nlm.nih.gov/11410522
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(3)
Recently, cDNAs have been identified that encode four human proteins (MRP2-5) with structural similarity to the multidrug resistance protein (MRP). Preliminary studies have shown that levels of mRNAs encoding MRP2, MRP3, and MRP5, are increased in so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d01894690f033c214b1d57ecd8c568d
https://pubmed.ncbi.nlm.nih.gov/10100721
https://pubmed.ncbi.nlm.nih.gov/10100721
Publikováno v:
The Journal of biological chemistry. 272(38)
Multidrug resistance protein, MRP, is a 190-kDa integral membrane phosphoglycoprotein that belongs to the ATP-binding cassette superfamily of transport proteins and is capable of conferring resistance to multiple chemotherapeutic agents. Previous stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9997cb74631ceecbea28a6d4cd5cca6a
https://pubmed.ncbi.nlm.nih.gov/9295302
https://pubmed.ncbi.nlm.nih.gov/9295302
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(1)
Acquired multidrug resistance is a major obstacle to a cure for small cell lung cancer (SCLC). Overexpression of the MDR1 gene occurs infrequently in multidrug-resistant SCLC cell lines. The multidrug resistance protein (MRP) can confer multidrug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c926ea6e3f44e49443ddf335a071b3
https://pubmed.ncbi.nlm.nih.gov/9815546
https://pubmed.ncbi.nlm.nih.gov/9815546
Publikováno v:
Molecular pharmacology. 49(6)
In vitro, overexpression of the human multidrug-resistance protein (MRP) causes a form of multidrug resistance similar to that conferred by P-glycoprotein, although the two proteins are only very distantly related. Studies with MRP-enriched membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6be4cfcfd61f3f8766ede2fb4be97e45
https://pubmed.ncbi.nlm.nih.gov/8649356
https://pubmed.ncbi.nlm.nih.gov/8649356
Autor:
M, Moore, X, Wang, Y F, Lu, M, Wormke, A, Craig, J H, Gerlach, R, Burghardt, R, Barhoumi, S, Safe
Publikováno v:
The Journal of biological chemistry. 269(16)
Wild-type MCF-7 human breast cancer cells were cultured for 3 months in 1 microM benzo[a]pyrene (BaP), and resistant clones were screened for inducibility of CYP1A1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). One of the BaP-resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::681057fe0758d1a4e9106f689302ff0c
https://pubmed.ncbi.nlm.nih.gov/7909315
https://pubmed.ncbi.nlm.nih.gov/7909315
Publikováno v:
Cancer research. 51(13)
Data obtained from clinical samples suggest that non-P-glycoprotein mechanisms of multidrug resistance are likely to be important in small cell lung cancer. The H69AR cell line was derived from the H69 small cell lung cancer cell line by selection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2668157b27d08166bb7568121bda6316
https://pubmed.ncbi.nlm.nih.gov/1675932
https://pubmed.ncbi.nlm.nih.gov/1675932
Publikováno v:
Molecular and General Genetics MGG. 152:13-18
Some physiological properties of a multiple-drug-resistant mutant with a permeability barrier to chloramphenicol and its isogenic parental strain were compared. The ATPase specific activity of plasma and mitochondrial membranes isolated from the muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b83132349838227e69b6c5b4b5c4bcf
https://doi.org/10.1007/bf00264934
https://doi.org/10.1007/bf00264934
Publikováno v:
Molecular and General Genetics MGG. 144:281-288
A mutant strain (2-20) isolated by growth on medium containing oligomycin and cycloheximide was also found to be cross resistant to antimyicn, cerulenin, chloramphenicol, tetracycline, triethyltin and triphenylmethylphosphonium bromide, but collatera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949b0c44e3ee423d51120cc872ad736d
https://doi.org/10.1007/bf00341726
https://doi.org/10.1007/bf00341726
Publikováno v:
Canadian Journal of Biochemistry. 58:565-572
Yeast cell wall, plasma membrane, total spheroplast, and total soluble protein fractions were isolated from exponentially growing Saccharomyces cerevisiae batch cultures. The cell wall, plasma membrane, and soluble protein fractions were obtained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca5f5f9463cb2facfe72554eef837e5
https://doi.org/10.1139/o80-077
https://doi.org/10.1139/o80-077