Zobrazeno 1 - 10
of 43
pro vyhledávání: '"J. H. G. Jonkman"'
Publikováno v:
European Journal of Clinical Pharmacology. 47:361-366
The indirect effect of diet on the single-and multiple-dose pharmacokinetics of sustained-release ketoprofen was studied in 16 healthy male volunteers. In an open, cross-over design, 200 mg ketoprofen was administered as a gastric-juice-resistant, su
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 25:355-366
The liquid—liquid extraction of tricyclic amines (antidepressants) was optimised using mixture experimental designs, the physical part of which was performed by a laboratory robotic system. This system was controlled and directed by a second, exter
Autor:
J. H. G. Jonkman, M. E. L. van der Burg, Th. Thien, A. J. M. Meulendijk, J. Bongaard van den Born, W. Bakker, N. G. M. Schipper, Frans W. H. M. Merkus, S. G. Romeijn, H. Van Belle, M. T. Esselink, D. J. Touw, J. A. Leusink, G. A. Rongen, R. Janknegt, K. Zech, G. Stoter, H. J. Guchelaar, H. Buikema, R. Huber, M. Kool, P. F. M. Kuks, E. Vellenga, M. de Boer-Dennert, J. W. M. Lenders, B. Steffens, L. E. Visser, E. G. E. de Vries, P. G. G. Gerlag, P. A. Van Zwieten, A.H. De Boer, Arijan J. Porsius, L. J. Bras, H. A. J. Struijker Boudier, B. M. de Jonah, H. A. Tissot van Patot, M. Doornbos, H. S. Lau, W. H. Van Gilst, T. A. Bruning, A. J. M. Loonen, John Verhoef, C. A. Verhagen, C. Meijer, J. J. Kraaijenga, A. K. S. van Musscher, A. Bakker, C. D. J. de Langen, P. H. M. van der Kuy, B. H. Ch. Stricker, J. Verweij, K. Ver Donck, P. A. M. Peeters, P.A. de Graeff, Jo Hermans, B. M. de Jongh, A. H. P. Paes, M. Hartmann, T. Dormans, J. H. M. Schellens, M. H. Steurs, D. de Boer, J. G. Grandiean, H. G. M. Heijerman, A. A. T. M. M. Vinks, M. Oosterga, J. J. H. Thijssen, J. Ma, G. Th. J. Fabius, H. Mattie, A. Hoeks, E. van Strijen, Harry Wesseling, P. Smits, J. van der Velden, J. Spek, D. R. A. Uges, A. S. T. Planting, J. J. M. van Mevel, C. H. Doorschot, B. Oosterhuis, P. C. Chang, M. H. A. Engberink, L. Van Bortel, N. H. Mulder
Publikováno v:
Pharmacy World & Science. 15:1-7
Autor:
M. M. Klauw, B. H. Ch. Stricker, J. P. Ottervanger, F. G. A. Meché, J. M. T. Griensven, H. H. P. J. Lemkes, J. M. Kroon, H. C. Schoemaker, A. F. Cohen, J. H. M. Schellens, W. Loos, B. Acker, M. Boer-Dennert, A. S. T. Planting, M. E. L. Burg, G. Stoter, R. Krediet, J. Verweij, E. E. Blaak, M. A. Baak, G. J. Kemerink, M. T. W. Pakbiers, G. A. K. Heidendal, W. H. M. Saris, S. Bouckaert, L. Vakaet, M. Dhont, J. P. Remon, S. A. J. Broek, P. A. Graeff, W. H. Gilst, D. J. Veldhuisen, H. L. Hillige, H. Wesseling, K. I. Lie, C. A. Gaillard, P. N. Es, P. W. Leeuw, L. M. A. B. Bortel, M. J. F. Kool, F. A. T. Lustermans, J. G. S. Breed, A. P. G. Hoeks, H. A. J. Struijker Boudier, R. P. Pickkers, P. Smits, H. Baadenhuysen, A. Laar, Th. Thien, M. M. Elseviers, M. E. Broe, A. J. A. M. Ven, P. P. Koopmans, W. H. M. Peters, T. B. Vree, J. W. M. Meer, E. Snoeck, A. Peer, M. Sack, M. Horton, G. Mannens, R. Woestenborghs, J. Heykants, R. Meibach, T. B. Witsen, H. A. Valkenburg, R. H. Stichele, B. Potter, P. Vyncke, M. G. Bogaert, J. Burggraaf, H. Wollersheim, J. Aalen, R. G. Schoemaker, X. Y. Du, W. A. Bax, E. Bos, P. R. Saxena, G. A. Rongen, P. N. M. Heiningen, H. R. Schwietert, J. M. Kortboyer, F. A. E. Sollie, C. Piraube, P. Desché, J. H. G. Jonkman, W. L. Blok, I. C. Gyssens, Y. A. Hekster, P. A. F. Jansen, R. C. Sival, J. F. Nieuwkerk, B. Klaverwiiden, E. A. Bruijn, O. Driessen
Publikováno v:
Pharmacy World & Science. 15:1-7
Publikováno v:
Clinical and Experimental Dermatology. 17:33-36
Summary In an open-label, parallel-group, randomized study percutaneous absorption of 14C-labelled amorolfine incorporated into a cream formulation was assessed in healthy male volunteers (n= 12). A single dose of 0·5 g of the 0·25% cream formulati
Publikováno v:
Biopharmaceutics & Drug Disposition. 12:661-672
Pharmacokinetics of 20 mg isosorbide-5-mononitrate (IS-5-MN) after single and multiple administration of two different tablet formulations were investigated in twelve healthy human subjects using an open, randomized, two-way crossover experimental de
Publikováno v:
Psychopharmacology. 106:S40-S42
In a pharmacological screen on drug-drug interactions performed in laboratory animals moclobemide potentiated at high doses the antiphlogistic/anti-inflammatory activity of ibuprofen. Therefore, a study was undertaken to determine in healthy voluntee
Autor:
J. H. G. Jonkman, L. R. Geertsema, M. G. C. Hendriks, J. T. Ebels, B. Oosterhuis, T. Hulot, G. Bianchetti, P. Dogterom
Publikováno v:
Fundamentalclinical pharmacology. 12(5)
In the present study we have compared the steady state biopharmaceutic characteristics of four diltiazem once daily controlled release capsules: Mono-Tildiem LP 300 (300 mg), Adizem XL (300 mg), Cardizem (300 mg) and Dilacor (240 mg). Sixteen healthy
Publikováno v:
European Journal of Clinical Pharmacology. 49
The pharmacokinetics and pharmacodynamics of recombinant human growth hormone (rhGH) were studied after a single subcutaneous dose given by jet-injection, and have been compared with the results obtained after conventional needle-injection. Twelve he
Publikováno v:
European Journal of Clinical Pharmacology. 46
We have studied the controlled-release properties and relative systemic availabilities of two dosages of the same controlled-release (CR) diltiazem tablet formulation by comparing them at steady state with those of an immediate-release formulation. W