Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. H. Cardellina"'
Autor:
Chris M. Ireland, R. K. Okuda, J. H. Cardellina, W. H. Gerwick, M. K. Harper and, S. C. Bobzin
Publikováno v:
Journal of Natural Products. 67:1201-1203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae38d98d03b29c699b6e5041710e9982
https://doi.org/10.1021/np049784a
https://doi.org/10.1021/np049784a
Autor:
T C, McKee, J H, Cardellina, R, Riccio, M V, D'Auria, M, Iorizzi, L, Minale, R A, Moran, R J, Gulakowski, J B, McMahon, R W, Buckheit
Publikováno v:
Journal of Medicinal Chemistry. 37:793-797
A total of 22 sulfated sterols isolated from marine sponges, ophiuroids (brittle stars), and asteroids (sea stars) were comparatively evaluated for their antiviral activity against HIV-1 and HIV-2. In general, sterols with sulfate groups at position
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54180050801639aa3a5a82df97009fc3
https://doi.org/10.1021/jm00032a012
https://doi.org/10.1021/jm00032a012
Autor:
Kenneth M. Snader, M. Tischler, T. C. McKee, J. H. Cardellina, T. G. McCloud, Michael R. Boyd, J. A. Beutler, Richard W. Fuller
Publikováno v:
Antiviral Chemistry and Chemotherapy. 4:167-172
Aqueous extracts of many marine invertebrates have exhibited some activity in the National Cancer Institute's primary screen for anti-HIV cytopathicity. Using a variety of techniques, including gel permeation, size exclusion and ion exchange chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9d5b6d3c34c1489fa5923a832637775
https://doi.org/10.1177/095632029300400306
https://doi.org/10.1177/095632029300400306
Autor:
K R, Gustafson, J H, Cardellina, J B, McMahon, R J, Gulakowski, J, Ishitoya, Z, Szallasi, N E, Lewin, P M, Blumberg, O S, Weislow, J A, Beutler
Publikováno v:
Journal of Medicinal Chemistry. 35:1978-1986
Extracts of Homalanthus nutans, a plant used in Samoan herbal medicine, exhibited potent activity in an in vitro, tetrazolium-based assay which detects the inhibition of the cytopathic effects of human immunodeficiency virus (HIV-1). The active const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69edc69704541da34fad43f64b8d815
https://doi.org/10.1021/jm00089a006
https://doi.org/10.1021/jm00089a006
Autor:
Gordon M. Cragg, Kenneth M. Snader, David J. Newman, Michael R. Boyd, T. G. McCloud, J H Cardellina nd
Publikováno v:
Ciba Foundation Symposium 185 - Ethnobotany and the Search for New Drugs
Between 1960 and 1981 the National Cancer Institute (NCI) screened 114,000 extracts of 35,000 plants, mainly collected in temperate regions. Of the three clinically active anticancer drugs so far discovered in that programme, none was isolated from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2610a118acc85f8c268750ef61f59f4
https://doi.org/10.1002/9780470514634.ch13
https://doi.org/10.1002/9780470514634.ch13
Publikováno v:
Natural product letters. 15(1)
Anti-HIV bioassay-guided fractionation of an organic extract of Ochanostachys amentacea provided an HIV-inhibitory polyacetylenic acid. The identity of this compound was established as (-)-17-hydroxy-9,11,13,15-octadecatetraynoic acid (1), also known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4895fb8580671feae218865c5cda98f
https://pubmed.ncbi.nlm.nih.gov/11547419
https://pubmed.ncbi.nlm.nih.gov/11547419
Autor:
Y F, Hallock, R C, Sowder, L K, Pannell, C B, Hughes, D G, Johnson, R, Gulakowski, J H, Cardellina, M R, Boyd
Publikováno v:
The Journal of organic chemistry. 65(1)
Four novel anti-HIV macrocyclic peptides containing 28-31 amino acid residues, named cycloviolins A-D, have been isolated from the hitherto unstudied tropical plant Leonia cymosa. Their primary structure, including amino acid composition and sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b264db2566ed08e73c8723177c1643b6
https://pubmed.ncbi.nlm.nih.gov/10813905
https://pubmed.ncbi.nlm.nih.gov/10813905
Autor:
B R, O'Keefe, T, Erim, J A, Beutler, J H, Cardellina, R J, Gulakowski, B L, Krepps, J B, McMahon, R C, Sowder, D G, Johnson, R W, Buckheit, S, Halliday, M R, Boyd
Publikováno v:
FEBS letters. 431(1)
Aqueous extracts of the New Zealand sponge Adocia sp. (Haplosclerida) displayed potent anticytopathic activity in CEM-SS cells infected with HIV-1. Protein fractions of the extract bound both to the viral coat protein gp120 and to the cellular recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b04f7332bdaee2a7afe820aa14953c79
https://pubmed.ncbi.nlm.nih.gov/9684871
https://pubmed.ncbi.nlm.nih.gov/9684871
Autor:
R J Gulakowski, P L Nara, J H Cardellina, J B McMahon, Robert W. Buckheit, Robert H. Shoemaker, R C Sowder, Barry R. O'Keefe, C M Laurencot, M I Rivera, Michael R. Boyd, Kirk R. Gustafson, M J Currens, L Wu, L E Henderson, Lewis K. Pannell, Toshiyuki Mori
We have isolated and sequenced a novel 11-kDa virucidal protein, named cyanovirin-N (CV-N), from cultures of the cyanobacterium (blue-green alga) Nostoc ellipsosporum. We also have produced CV-N recombinantly by expression of a corresponding DNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795c43f71b229cbdfeac4a0c1f4f3f55
https://europepmc.org/articles/PMC163952/
https://europepmc.org/articles/PMC163952/
Autor:
Michael R. Boyd, J H Cardellina nd, James B. McMahon, Richard W. Fuller, D L Galinis, Robert J. Gulakowski, Tawnya C. McKee
Publikováno v:
Journal of medicinal chemistry. 39(22)
The delta 7,8 olefinic linkages within (+)-calanolide A(1) and (-)-calanolide B(2) were catalytically reduced to determine impact on the anti-HIV activity of the parent compounds. In addition, a series of structure modifications of the C-12 hydroxyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0b1e0b5276ff8e337af0660cd908cc
https://pubmed.ncbi.nlm.nih.gov/8893846
https://pubmed.ncbi.nlm.nih.gov/8893846