Zobrazeno 1 - 10
of 58
pro vyhledávání: '"J. H. Klippel"'
Autor:
G G, Illei, J H, Klippel
Publikováno v:
Rheumatic Disease Clinics of North America. 26:63-73
The removal of pathologic humors by various methods is an ancient medical remedy used in the management of diseases whose pathophysiology is poorly understood and whose effective treatment modalities are lacking. The contemporary means for such an ap
Autor:
J. H. Klippel
Publikováno v:
Archives of Internal Medicine. 151:2389-2393
Publikováno v:
The Journal of rheumatology. 27(8)
To determine if clinically asymptomatic knee joints in patients with recent onset arthritis reveal histological evidence of synovitis.As part of a prospective study of patients with synovitis of less than one year duration, we performed blind needle
Publikováno v:
Arthritis and rheumatism. 43(4)
This report describes the case of a patient with multicentric reticulohistiocytosis. Immunohistochemical analysis revealed prominent markers of monocyte/macrophage origin, as well as the presence of tumor necrosis factor alpha, interleukin-1beta (IL-
Autor:
H S, El-Gabalawy, R, Goldbach-Mansky, D, Smith, T, Arayssi, S, Bale, P, Gulko, C, Yarboro, R L, Wilder, J H, Klippel, H R, Schumacher
Publikováno v:
Arthritis and rheumatism. 42(8)
To determine how HLA alleles are associated with the clinical disease patterns of patients with synovitis of recent onset.The HLA alleles A, B, C, DRbeta1, and DQbeta1 were determined in a cohort of 211 patients (mean age 42 years, 64% female, 79% wh
Autor:
J S, Smolen, V, Strand, M, Cardiel, S, Edworthy, D, Furst, D, Gladman, C, Gordon, D A, Isenberg, J H, Klippel, M, Petri, L, Simon, P, Tugwell, F, Wolfe
Publikováno v:
The Journal of rheumatology. 26(2)
The OMERACT module on systemic lupus erythematosus (SLE) dealt with the definition of preliminary core sets of outcome domains for randomized clinical trials (RCT) and longitudinal observational studies (LOS). After lectures introducing the problems
Autor:
J H, Klippel
Publikováno v:
Bailliere's clinical rheumatology. 12(3)
Over the past decade, cytotoxic drugs have come to assume an increasingly important role in the management of systemic lupus erythematosus. Intravenous cyclophosphamide has become the standard treatment for lupus affecting major organs, in particular
Autor:
J H Klippel, G G Illei
Publikováno v:
Lupus. 7(9)
Lupus nephritis can be managed successfully in the majority of cases; most therapies, however, are associated with significant side-effects. Several new agents aiming at specific stages in the pathogenesis of lupus are in different phases of clinical
Autor:
I O, Tassiulas, I, Aksentijevich, J E, Salmon, Y, Kim, C H, Yarboro, E M, Vaughan, J C, Davis, D L, Scott, H A, Austin, J H, Klippel, J E, Balow, M F, Gourley, D T, Boumpas
Publikováno v:
Clinical nephrology. 50(1)
The presence of the D (deletion) allele at the angiotensin converting enzyme (ACE) gene has been associated with a) adverse vascular events contributing to early mortality and b) progressive deterioration of renal function in a variety of chronic glo
Autor:
J C, Davis, H, Austin, D, Boumpas, T A, Fleisher, C, Yarboro, A, Larson, J, Balow, J H, Klippel, D, Scott
Publikováno v:
Arthritis and rheumatism. 41(2)
To determine the safety and tolerability, as well as the clinical and immunologic effects, of 2-chloro-2'-deoxyadenosine (2-CdA) in patients with systemic lupus erythematosus-associated glomerulonephritis.In a phase I study, 12 patients with prolifer