Zobrazeno 1 - 10
of 112
pro vyhledávání: '"J. Guise"'
Autor:
Amanda J. Guise, Santosh A. Misal, Richard Carson, Jen-Hwa Chu, Hannah Boekweg, Daisha Van Der Watt, Nora C. Welsh, Thy Truong, Yiran Liang, Shanqin Xu, Gina Benedetto, Jake Gagnon, Samuel H. Payne, Edward D. Plowey, Ryan T. Kelly
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113636- (2024)
Summary: A limitation of conventional bulk-tissue proteome studies in amyotrophic lateral sclerosis (ALS) is the confounding of motor neuron (MN) signals by admixed non-MN proteins. Here, we leverage laser capture microdissection and nanoPOTS single-
Externí odkaz:
https://doaj.org/article/8a6acb1de53f412fbde8d06f4b44f6e9
Autor:
Kimino Fujimura, Amanda J. Guise, Tojo Nakayama, Christoph N. Schlaffner, Anais Meziani, Mukesh Kumar, Long Cheng, Dylan J. Vaughan, Andrew Kodani, Simon Van Haren, Kenneth Parker, Ofer Levy, Ann F. Durbin, Irene Bosch, Lee Gehrke, Hanno Steen, Ganeshwaran H. Mochida, Judith A. Steen
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106909- (2023)
Summary: Characterizing perturbation of molecular pathways in congenital Zika virus (ZIKV) infection is critical for improved therapeutic approaches. Leveraging integrative systems biology, proteomics, and RNA-seq, we analyzed embryonic brain tissues
Externí odkaz:
https://doaj.org/article/51cd38694972434695fcef207fb0e48f
Autor:
Hannah Boekweg, Daisha Van Der Watt, Thy Truong, S. Madisyn Johnston, Amanda J. Guise, Edward D. Plowey, Ryan T. Kelly, Samuel H. Payne
Publikováno v:
Journal of Proteome Research. 21:182-188
The goal of proteomics is to identify and quantify the complete set of proteins in a biological sample. Single-cell proteomics specializes in the identification and quantitation of proteins for individual cells, often used to elucidate cellular heter
Autor:
J. Guise, H. Ratovo, S. Blin, L. Cerutti, J.-B. Rodriguez, E. Centeno, M. Thual, T. Taliercio
Publikováno v:
2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz).
Publikováno v:
2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz).
Autor:
Yiran Liang, Romain Huguet, Khatereh Motamedchaboki, Amanda J. Guise, Edward D. Plowey, Yongzheng Cong, Thy Truong, Daniel Lopez-Ferrer, Ying Zhu, Ryan T. Kelly, Santosh A. Misal
Publikováno v:
Chemical Science
We report on the combination of nanodroplet sample preparation, ultra-low-flow nanoLC, high-field asymmetric ion mobility spectrometry (FAIMS), and the latest-generation Orbitrap Eclipse Tribrid mass spectrometer for greatly improved single-cell prot
Autor:
Preeti Joshi, Todd M Greco, Amanda J Guise, Yang Luo, Fang Yu, Alexey I Nesvizhskii, Ileana M Cristea
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-21 (2013)
Abstract Histone deacetylases (HDACs) are a diverse family of essential transcriptional regulatory enzymes, that function through the spatial and temporal recruitment of protein complexes. As the composition and regulation of HDAC complexes are only
Externí odkaz:
https://doaj.org/article/6f5a66e983e341378ad74ddab6ea1460
Publikováno v:
Viruses, Vol 5, Iss 7, Pp 1607-1632 (2013)
Emerging evidence highlights a critical role for protein acetylation during herpesvirus infection. As prominent modulators of protein acetylation, histone deacetylases (HDACs) are essential transcriptional and epigenetic regulators. Not surprisingly,
Externí odkaz:
https://doaj.org/article/54bf770ad8c54f1f9949314c5b2b0c30
Autor:
Karin R McDonald, Amanda J Guise, Parham Pourbozorgi-Langroudi, Ileana M Cristea, Virginia A Zakian, John A Capra, Nasim Sabouri
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006238 (2016)
Replicative DNA helicases expose the two strands of the double helix to the replication apparatus, but accessory helicases are often needed to help forks move past naturally occurring hard-to-replicate sites, such as tightly bound proteins, RNA/DNA h
Externí odkaz:
https://doaj.org/article/71449be1600541e390921736ba318052
Autor:
Daisha Van Der Watt, Amanda J. Guise, Hannah Boekweg, Edward D. Plowey, Thy Truong, Samuel H. Payne, Ryan T. Kelly
Single cell proteomics is an emerging sub-field within proteomics with the potential to revolutionize our understanding of cellular heterogeneity and interactions. Recent efforts have largely focused on technological advancements in sample preparatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa49611e54cd4ed422cef65257ffa736
https://doi.org/10.1101/2021.08.17.456676
https://doi.org/10.1101/2021.08.17.456676