Zobrazeno 1 - 10
of 239
pro vyhledávání: '"J. Grzesik"'
Publikováno v:
Radioengineering, Vol 21, Iss 4, Pp 974-978 (2012)
We introduce a novel microwave imaging technique for breast cancer detection. Our approach provides a one-pass inverse image solution, which is completely new and unprecedented, unrelated to tomography or radar-based algorithms, and unburdened by the
Externí odkaz:
https://doaj.org/article/e9cfcf3f147c4540869063bea43291f1
Autor:
Tozen Ozkan-Nikitaras, Dominika J. Grzesik, Lisa E. L. Romano, J. P. Chapple, Peter J. King, Carol C. Shoulders
Publikováno v:
Cells, Vol 13, Iss 15, p 1255 (2024)
Cholesterol is required to maintain the functional integrity of cellular membrane systems and signalling pathways, but its supply must be closely and dynamically regulated because excess cholesterol is toxic. Sterol regulatory element-binding protein
Externí odkaz:
https://doaj.org/article/5a2f4b66c5b64dc68abfa844131903f9
Autor:
Susheel K. Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Pratik R. Chheda, Chen Kang, David M. Kern, Chau My-Ta, Joshua Maurer, John Heebink, Eva E. Gerber, Wojciech J. Grzesik, Macaulay Elliot-Hudson, Yanhui Zhang, Phillip Key, Chaitanya A. Kulkarni, Joseph W. Beals, Gordon I. Smith, Isaac Samuel, Jessica K. Smith, Peter Nau, Yumi Imai, Ryan D. Sheldon, Eric B. Taylor, Daniel J. Lerner, Andrew W. Norris, Samuel Klein, Stephen G. Brohawn, Robert Kerns, Rajan Sah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Type 2 diabetes is associated with insulin resistance, impaired insulin secretion and liver steatosis. Here the authors report a proof-of-concept study for small molecule SWELL1 modulators as a therapeutic approach to treat diabetes and associated li
Externí odkaz:
https://doaj.org/article/f4d1fee19c624c0a9f1b40ef56f78e04
Publikováno v:
Physiological Reports, Vol 10, Iss 17, Pp n/a-n/a (2022)
Abstract Type 2 diabetes and obesity are associated with increased risk of cardiovascular disease, including heart failure. A hallmark of these dysmetabolic states is hyperinsulinemia and decreased cardiac reserve. However, the direct effects of hype
Externí odkaz:
https://doaj.org/article/6ebd1486d7974382b6d431a1605fd1c5
Autor:
Arpit Sharma, Lalita Oonthonpan, Ryan D Sheldon, Adam J Rauckhorst, Zhiyong Zhu, Sean C Tompkins, Kevin Cho, Wojciech J Grzesik, Lawrence R Gray, Diego A Scerbo, Alvin D Pewa, Emily M Cushing, Michael C Dyle, James E Cox, Chris Adams, Brandon S Davies, Richard K Shields, Andrew W Norris, Gary Patti, Leonid V Zingman, Eric B Taylor
Publikováno v:
eLife, Vol 8 (2019)
Metabolic cycles are a fundamental element of cellular and organismal function. Among the most critical in higher organisms is the Cori Cycle, the systemic cycling between lactate and glucose. Here, skeletal muscle-specific Mitochondrial Pyruvate Car
Externí odkaz:
https://doaj.org/article/13cd1adfdce945bdbb60969f1404d117
Akademický článek
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Autor:
Calvin S. Carter, Sunny C. Huang, Charles C. Searby, Benjamin Cassaidy, Michael J. Miller, Wojciech J. Grzesik, Ted B. Piorczynski, Thomas K. Pak, Susan A. Walsh, Michael Acevedo, Qihong Zhang, Kranti A. Mapuskar, Ginger L. Milne, Antentor O. Hinton Jr., Deng-Fu Guo, Robert Weiss, Kyle Bradberry, Eric B. Taylor, Adam J. Rauckhorst, David W. Dick, Vamsidhar Akurathi, Kelly C. Falls-Hubert, Brett A. Wagner, Walter A. Carter, Kai Wang, Andrew W. Norris, Kamal Rahmouni, Garry R. Buettner, Jason M. Hansen, Douglas R. Spitz, E. Dale Abel, Val C. Sheffield
Publikováno v:
Am J Physiol Endocrinol Metab
Carter et al. report that exposure to static magnetic and electric fields (sBE), for as little as 3 days, reverses glucose intolerance and insulin resistance in diet-induced and genetic mouse models of type 2 diabetes (1). They hypothesize that sBE t
Autor:
Walter A. Carter, Kai Wang, Deng-Fu Guo, Kelly C. Falls-Hubert, Calvin S. Carter, Ted B. Piorczynski, Benjamin Cassaidy, Brett A. Wagner, Douglas R. Spitz, Michael J. Miller, Adam J. Rauckhorst, Charles Searby, Robert M. Weiss, Kyle Bradberry, Eric B. Taylor, Kranti A. Mapuskar, Michael R. Acevedo, Qihong Zhang, E. Dale Abel, David W. Dick, Vamsidhar Akurathi, Andrew W. Norris, Jason M. Hansen, Wojciech J. Grzesik, Sunny C. Huang, Garry R. Buettner, Kamal Rahmouni, Susan A. Walsh, Thomas Pak, Val C. Sheffield, Antentor Othrell Hinton, Ginger L. Milne
Publikováno v:
Cell Metab
Summary Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained appro
Akademický článek
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Autor:
Andrew W. Norris, Brett A. Wagner, Val C. Sheffield, Susan A. Walsh, Kyle Bradberry, Kai Wang, Ginger L. Milne, Deng-Fu Guo, Kamal Rahmouni, Walter A. Carter, Robert M. Weiss, Adam J. Rauckhorst, Antentor Othrell Hinton, Eric B. Taylor, Douglas R. Spitz, David W. Dick, Michael R. Acevedo, Sunny C. Huang, Ted B. Piorczynski, Charles Searby, Vamsidhar Akurathi, Jason Hansen, Garry R. Buettner, Qihong Zhang, Calvin S. Carter, Wojciech J. Grzesik, Benjamin Cassaidy, E. Dale Abel, Kranti A. Mapuskar, Kelly C. Falls-Hubert, Thomas Pak, Michael J. Miller
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 320:E1004-E1005