Zobrazeno 1 - 10
of 326
pro vyhledávání: '"J. Gruß"'
Autor:
Benjamin A. Nacev, Yakshi Dabas, Matthew R. Paul, Christian Pacheco, Michelle Mitchener, Yekaterina Perez, Yan Fang, Alexey A. Soshnev, Douglas Barrows, Thomas Carroll, Nicholas D. Socci, Samantha C. St. Jean, Sagarika Tiwari, Michael J. Gruss, Sebastien Monette, William D. Tap, Benjamin A. Garcia, Tom Muir, C. David Allis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dysregulated epigenetic states are a hallmark of cancer and often arise from genetic alterations in epigenetic regulators. This includes missense mutations in histones, which, together with associated DNA, form nucleosome core particles. How
Externí odkaz:
https://doaj.org/article/a8ab4f3e792a49f58af3860467b6cc16
Autor:
Benjamin A. Nacev, Yakshi Dabas, Matthew R. Paul, Christian Pacheco, Michelle Mitchener, Yekaterina Perez, Yan Fang, Alexey A. Soshnev, Douglas Barrows, Thomas Carroll, Nicholas D. Socci, Samantha C. St. Jean, Sagarika Tiwari, Michael J. Gruss, Sebastien Monette, William D. Tap, Benjamin A. Garcia, Tom Muir, C. David Allis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f1c8467acfda4feead04f5a45957d930
Autor:
Zhenzhen Chu, Oliver J. Gruss
Publikováno v:
Cells, Vol 11, Iss 7, p 1189 (2022)
Centrosomes represent main microtubule organizing centers (MTOCs) in animal cells. Their duplication in S-phase enables the establishment of two MTOCs in M-phase that define the poles of the spindle and ensure equal distribution of chromosomes and ce
Externí odkaz:
https://doaj.org/article/8ff07abfbbcd4263a45f7e839a6f50c5
Autor:
Oliver Glass, Ricardo Henao, Keyur Patel, Cynthia D. Guy, Hans J. Gruss, Wing‐Kin Syn, Cynthia A. Moylan, Robert Streilein, Russell Hall, Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
The severity of hepatic fibrosis is the primary predictor of liver‐related morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). Unfortunately, noninvasive serum biomarkers for NAFLD‐associated fibrosis are limited. W
Externí odkaz:
https://doaj.org/article/15c5b601b1564633b905485bbd685159
Autor:
Daigo Inoue, Manuel Stemmer, Thomas Thumberger, Thomas Ruppert, Felix Bärenz, Joachim Wittbrodt, Oliver J. Gruss
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The assembly of the first centrosome occurs upon fertilisation when male centrioles recruit pericentriolar material from the egg cytoplasm. Here the authors identify Wdr8 as a maternally essential protein that is required for centrosome assembly duri
Externí odkaz:
https://doaj.org/article/2ba59a147ad242dbae4f9759a15d0dbe
Publikováno v:
Cell and Tissue Research.
Variations in the gene encoding filamin-A-interacting protein 1 (FILIP1) were identified to be associated with a combination of neurological and muscular symptoms. While FILIP1 was shown to regulate motility of brain ventricular zone cells, a process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776ed5661bca627b1ff40eb1fd4d6b6b
https://doi.org/10.1007/s00441-023-03776-4
https://doi.org/10.1007/s00441-023-03776-4
Publikováno v:
GENETICS.
TWIST1 is a basic helix-loop-helix (bHLH) transcription factor in humans that functions in mesoderm differentiation. TWIST1 primarily regulates genes as a transcriptional repressor often through TWIST-Box domain-mediated protein–protein interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8c85824a91fed38dafeb17e1513eca
https://doi.org/10.1093/genetics/iyad066
https://doi.org/10.1093/genetics/iyad066
Autor:
Henrik Daub, Axel Ullrich, Matt Cotten, Stefan Müller, György Kéri, Zoltán Horváth, László Őrfi, Dirk Brehmer, Heidrun Degen, Martina Weber, Stephanie Blencke, Josef Wissing, Jan Eickhoff, Oliver J. Gruss, Klaus Godl
Supplementary Methods from Proteomic Characterization of the Angiogenesis Inhibitor SU6668 Reveals Multiple Impacts on Cellular Kinase Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789ba711eb15997d730538decf8d62cc
https://doi.org/10.1158/0008-5472.22363805
https://doi.org/10.1158/0008-5472.22363805
Autor:
Henrik Daub, Axel Ullrich, Matt Cotten, Stefan Müller, György Kéri, Zoltán Horváth, László Őrfi, Dirk Brehmer, Heidrun Degen, Martina Weber, Stephanie Blencke, Josef Wissing, Jan Eickhoff, Oliver J. Gruss, Klaus Godl
Supplementary Figure 1 from Proteomic Characterization of the Angiogenesis Inhibitor SU6668 Reveals Multiple Impacts on Cellular Kinase Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0756a04157a10dd2aec096fdfd2a8fbd
https://doi.org/10.1158/0008-5472.22363808.v1
https://doi.org/10.1158/0008-5472.22363808.v1
Autor:
Henrik Daub, Axel Ullrich, Matt Cotten, Stefan Müller, György Kéri, Zoltán Horváth, László Őrfi, Dirk Brehmer, Heidrun Degen, Martina Weber, Stephanie Blencke, Josef Wissing, Jan Eickhoff, Oliver J. Gruss, Klaus Godl
Knowledge about molecular drug action is critical for the development of protein kinase inhibitors for cancer therapy. Here, we establish a chemical proteomic approach to profile the anticancer drug SU6668, which was originally designed as a selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3077c98eee86ccde664df9808edb82aa
https://doi.org/10.1158/0008-5472.c.6493904.v1
https://doi.org/10.1158/0008-5472.c.6493904.v1