Zobrazeno 1 - 10
of 87
pro vyhledávání: '"J. Griese"'
Autor:
Martin Högbom, Hugo Lebrette, Annika Johansson, Riccardo Diamanti, Julia J. Griese, Vivek Srinivas, Anders Nordström
R2-like ligand-binding oxidase (R2lox) is a ferritin-like protein that harbours a heterodinuclear manganese–iron active site. Although R2lox function is yet to be established, the enzyme binds a fatty acid ligand coordinating the metal centre and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d57653c3aeb17f3ebaa317257e232cc
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468091
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468091
Akademický článek
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Publikováno v:
Nucleic Acids Research
The iron-dependent regulator IdeR is the main transcriptional regulator controlling iron homeostasis genes in Actinobacteria, including species from the Corynebacterium, Mycobacterium and Streptomyces genera, as well as the erythromycin-producing bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804fc9b61d867793c23fd1d012155a67
https://doi.org/10.1101/2021.02.12.430932
https://doi.org/10.1101/2021.02.12.430932
Autor:
Sebastian Fenn, Christian B Schiller, Julia J Griese, Harald Duerr, Sabine Imhof-Jung, Christian Gassner, Joerg Moelleken, Joerg Thomas Regula, Wolfgang Schaefer, Markus Thomas, Christian Klein, Karl-Peter Hopfner, Hubert Kettenberger
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61953 (2013)
Bispecific antibodies are considered as a promising class of future biotherapeutic molecules. They comprise binding specificities for two different antigens, which may provide additive or synergistic modes of action. There is a wide variety of design
Externí odkaz:
https://doaj.org/article/d35ff357608844489f263722db7ce824
Publikováno v:
Journal of Biological Inorganic Chemistry
JBIC Journal of Biological Inorganic Chemistry
JBIC Journal of Biological Inorganic Chemistry
R2-like ligand-binding oxidases (R2lox) assemble a heterodinuclear Mn/Fe cofactor which performs reductive dioxygen (O2) activation, catalyzes formation of a tyrosine–valine ether cross-link in the protein scaffold, and binds a fatty acid in a puta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe8064d2a24f3c68ab750077753d6af
http://europepmc.org/articles/PMC6399176
http://europepmc.org/articles/PMC6399176
Publikováno v:
Journal of Biological Inorganic Chemistry
JBIC Journal of Biological Inorganic Chemistry
JBIC Journal of Biological Inorganic Chemistry
R2-like ligand-binding oxidases contain a dinuclear metal cofactor which can consist either of two iron ions or one manganese and one iron ion, but the heterodinuclear Mn/Fe cofactor is the preferred assembly in the presence of MnII and FeII in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2aaf793d95f6e6bf757d3fce290950
http://europepmc.org/articles/PMC6060897
http://europepmc.org/articles/PMC6060897
Autor:
Zachary R. Smith, Jürgen Eirich, Effie K. Miller, Martin Högbom, Pearson T. Maugeri, Rui M. M. Branca, Julia J. Griese, Hannah S. Shafaat
Publikováno v:
Journal of the American Chemical Society
The heterobimetallic R2lox protein binds both manganese and iron ions in a site-selective fashion and activates oxygen, ultimately performing C-H bond oxidation to generate a tyrosine-valine crosslink near the active site. In this work, we demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b321a334df30918024c4abc8ed747e33
https://doi.org/10.1021/jacs.7b11966
https://doi.org/10.1021/jacs.7b11966
Autor:
Martin Högbom, Zachary R. Smith, Camille R. Schneider, Julia J. Griese, Hannah S. Shafaat, Rui M. M. Branca, Effie C. Kisgeropoulos
Publikováno v:
J Am Chem Soc
Journal of the American Chemical Society
Journal of the American Chemical Society
Heterobimetallic Mn/Fe proteins represent a new cofactor paradigm in bioinorganic chemistry and pose countless outstanding questions. The assembly of the active site defies common chemical convention by contradicting the Irving-Williams series, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6c78f37cd8f69d44fda772c01e0948
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-411216
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-411216
Autor:
Klaus-Peter Künkele, Christian Gassner, Manfred Schwaiger, Tobias Manigold, Lothar Kling, Christian Klein, Diana Weininger, Jörg T. Regula, Philippe Ringler, Matthias E. Lauer, Alexandra Graff-Meyer, Sebastian Fenn, Julia J. Griese, Michael Molhoj, Hubert Kettenberger, Birgit Bossenmaier, Ulrich Brinkmann, Karl-Peter Hopfner, Steffen Dickopf, Claudio Sustmann, Henning Stahlberg, Wolfgang Schaefer
Publikováno v:
mAbs
High specificity accompanied with the ability to recruit immune cells has made recombinant therapeutic antibodies an integral part of drug development. Here we present a generic approach to generate two novel IgG-derived antibody formats that are bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0864e4ef485578dafe4129bccf4ef83
https://pubmed.ncbi.nlm.nih.gov/31526159
https://pubmed.ncbi.nlm.nih.gov/31526159
Autor:
Xiaodong Zou, Hongyi Xu, Jingjing Zhao, Hugo Lebrette, Max T. B. Clabbers, Julia J. Griese, Martin Högbom
Micro-crystal electron diffraction (MicroED) has recently shown potential for structural biology. It enables studying biomolecules from micron-sized 3D crystals that are too small to be studied by conventional X-ray crystallography. However, to the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21736994d985b3930a653242f5885bf7
https://doi.org/10.1101/600387
https://doi.org/10.1101/600387