Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. Greenamyre"'
Publikováno v:
Bio-Protocol, Vol 11, Iss 17 (2021)
Missense mutations in leucine rich-repeat kinase 2 (LRRK2) cause forms of familial Parkinson’s disease and have been linked to ‘idiopathic’ Parkinson’s disease. Assessment of LRRK2 kinase activity has been very challenging due to its size, co
Externí odkaz:
https://doaj.org/article/9877a7a17d644d1c87f28fb8afcec962
Autor:
Yoel Sadovsky, Ivet Bahar, Charleen T. Chu, Yu-Jia Zhai, Karolina Mikulska-Ruminska, Sergey Korolev, Timothy J Greenamyre, Jie Sun, Rong-Rong He, Alexandr A. Kapralov, Yulia Y. Tyurina, Haider H. Dar, Valerian E. Kagan, Hülya Bayır, Ming-Hai Pan, Teresa G. Hastings, Vladimir A. Tyurin, Hai-Biao Gong, Wanyang Sun, Ofer Beharier, Gaowei Mao, Ian J. Miller, Plamena R. Angelova, Andrew A. Amoscato, Andrey Y. Abramov, Dan-Hua Lu, Wen-Jun Duan, Indira H. Shrivastava, Tamil S. Anthonymuthu
Publikováno v:
Nature chemical biology
Ferroptosis, triggered by discoordination of iron, thiols and lipids, leads to the accumulation of 15-hydroperoxy (Hp)-arachidonoyl-phosphatidylethanolamine (15-HpETE-PE), generated by complexes of 15-lipoxygenase (15-LOX) and a scaffold protein, pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdc4b22b9ca22fad6e00700b7358bac
http://europepmc.org/articles/PMC8152680
http://europepmc.org/articles/PMC8152680