Zobrazeno 1 - 10
of 129
pro vyhledávání: '"J. Grant Collins"'
Autor:
Kartika Wardhani, Aviva Levina, Biyun Sun, Haipei Zou, Georges E. R. Grau, F. Richard Keene, J. Grant Collins, Peter A. Lay
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 664 (2024)
Selective staining of extracellular vesicles (EVs) is a major challenge for diagnostic and therapeutic applications. Herein, the EV labeling properties of a new class of tetranuclear polypyridylruthenium(II) complexes, Rubb7-TNL and Rubb7-TL, as phos
Externí odkaz:
https://doaj.org/article/40a8d0f6a6834389b75a9b72abc5d2bc
Autor:
Madhu Sundaraneedi, Ramon M. Eichenberger, Rafid Al-Hallaf, Dai Yang, Javier Sotillo, Siji Rajan, Phurpa Wangchuk, Paul R. Giacomin, F. Richard Keene, Alex Loukas, J. Grant Collins, Mark S. Pearson
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 1, Pp 1-7 (2018)
Over 4.5 billion people are at risk of infection with soil transmitted helminths and there are concerns about the development of resistance to the handful of frontline nematocides in endemic populations. We investigated the anti-nematode efficacy of
Externí odkaz:
https://doaj.org/article/a91232b743cc4e6b8a2f28efb1352c1c
Autor:
Biyun Sun, Ian F. Musgrave, Anthony I. Day, Kirsten Heimann, F. Richard Keene, J. Grant Collins
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
The toxicity (IC50) of a series of mononuclear ruthenium complexes containing bis[4(4′-methyl-2,2′-bipyridyl)]-1,n-alkane (bbn) as a tetradentate ligand against three eukaryotic cell lines—BHK (baby hamster kidney), Caco-2 (heterogeneous human
Externí odkaz:
https://doaj.org/article/16af51d6347e48f98863dca8efb6ecb7
Autor:
Kartika Wardhani, Aviva Levina, Biyun Sun, Georges E. R. Grau, F. Richard Keene, J. Grant Collins, Peter A. Lay
Publikováno v:
Chemical Communications.
A tetranuclear Ru dye for selective staining of extracellular vesicles for studies of in vitro blood–brain barrier permeability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79cad6c027bca842394b23a110b95876
https://doi.org/10.1039/d2cc05827h
https://doi.org/10.1039/d2cc05827h
Autor:
Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006134 (2017)
Schistosomiasis affects over 200 million people and there are concerns whether the current chemotherapeutic control strategy (periodic mass drug administration with praziquantel (PZQ)-the only licenced anti-schistosome compound) is sustainable, neces
Externí odkaz:
https://doaj.org/article/092fa447a02a4f12a7290df14a2f9ef0
Publikováno v:
Coordination Chemistry Reviews. 375:134-147
Due to the clinical success and limitations of platinum-based anticancer drugs, there has been considerable interest in the development of new therapeutic agents based upon other transition metals, in particular ruthenium. There have now been many st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bf1733cc67e9724a43ace0e6ae0fcdd
https://doi.org/10.1016/j.ccr.2017.11.011
https://doi.org/10.1016/j.ccr.2017.11.011
Autor:
J. Grant Collins, Jonathan A. Butler, Robert K. Poole, Biyun Sun, F. Richard Keene, Xin Li, Ruby E. M. Kell, Xuewen Liu, Hannah M. Southam
Publikováno v:
ChemPlusChem
The cis-α isomer of [Ru(bb7)(dppz)]2+ {dppz = dipyrido[3,2-a:2′,3′-c]phenazine; bb7 = bis[4(4'-methyl-2,2'-bipyridyl)]-1,7-alkane} has been synthesised. The minimum inhibitory concentrations and the minimum bactericidal concentrations of [Ru(bb7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769a375e7bb5ec14725f297abb49914d
https://doi.org/10.1002/cplu.201800042
https://doi.org/10.1002/cplu.201800042
Autor:
Ramon M. Eichenberger, Paul R. Giacomin, Phurpa Wangchuk, Alex Loukas, J. Grant Collins, Dai Yang, Javier Sotillo, Madhu K. Sundaraneedi, Mark S. Pearson, Siji Rajan, F. Richard Keene, Rafid Alhallaf
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 1, Pp 1-7 (2018)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Over 4.5 billion people are at risk of infection with soil transmitted helminths and there are concerns about the development of resistance to the handful of frontline nematocides in endemic populations. We investigated the anti-nematode efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f5a227a3fded1ad3ebf7866c5a30b3
http://www.sciencedirect.com/science/article/pii/S2211320717301082
http://www.sciencedirect.com/science/article/pii/S2211320717301082
Autor:
Bemnet Amare Tedla, Madhu K. Sundaraneedi, F. Richard Keene, Alex Loukas, Alaina J. Ammit, Mark S. Pearson, J. Grant Collins
Publikováno v:
ChemistrySelect. 2:10668-10672
Mitogen-activated protein kinase phosphatases (MKPs) are over-expressed in many cancers. The increased levels of MKP enzymes protect cells from apoptosis induced by anticancer drugs, and thereby decrease the efficacy of the drug. Consequently, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc66d206de62252011adbdb2153cbda6
https://doi.org/10.1002/slct.201702118
https://doi.org/10.1002/slct.201702118
Autor:
Anil K. Gorle, J. Grant Collins, F. Richard Keene, Elizabeth J. Harry, Clifford E. Woodward, Amy L. Bottomley
Publikováno v:
Molecular BioSystems. 13:677-680
Condensation studies of chromosomal DNA in E. coli with a tetranuclear ruthenium complex are carried out and images obtained with wide-field fluorescence microscopy. Remarkably different condensate morphologies resulted, depending upon the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8dcdd859c1926efa798a45b6f9c38b
https://doi.org/10.1039/c6mb00753h
https://doi.org/10.1039/c6mb00753h