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pro vyhledávání: '"J. Graham Goddard"'
Autor:
Jason J. Wu, Gabor Tigyi, L. David Tomei, James R. Erickson, Katsumasa Kawanishi, Michael C. Kiefer, J. Graham Goddard
Publikováno v:
Journal of Biological Chemistry. 273:1506-1510
We have functionally expressed the human cDNA encoding the putative lysophosphatidic acid (LPA) receptor Edg-2 (Vzg-1) in Saccharomyces cerevisiae in an attempt to determine the agonist specificity of this G-protein-coupled receptor. LPA activated th
Publikováno v:
Free Radical Research Communications. 17:177-185
In the past, antioxidant and chelator studies have implicated a role for iron-dependent oxidative damage in tissues subjected to ischaemia followed by reperfusion. As ferritin is a major source of iron in non-muscular organs and therefore a potential
Publikováno v:
Clinical Pharmacology & Therapeutics. 48:255-261
Pharmacokinetic studies have been carried out with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1). HPLC analysis of serum of a normal volunteer and seven transfusional iron loaded patients who ingested a 3 gm dose of L1 revealed that L
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