Zobrazeno 1 - 10
of 686
pro vyhledávání: '"J. Gollob"'
Autor:
Amanda Braga Figueiredo, Milton José Barros e Silva, Guilherme Ferreira de Britto Evangelista, Nayane Alves de Lima Galdino, Larissa de Melo Kuil, Iasmim Polido Santos, Kátia Luciano Pereira Morais, Clara Maciel Cavalcanti, Luciana Facure Moredo, João Pedreira Duprat-Neto, Kenneth J Gollob
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32624- (2024)
The treatment for stage III melanoma has advanced significantly, nevertheless, a substantial proportion of patients experience relapse. Neoadjuvant immune checkpoint blockade has emerged as a promising approach, allowing early micrometastatic disease
Externí odkaz:
https://doaj.org/article/e8156cfed6ac4ff7b8cedd9f63a2d4e5
Autor:
Patrícia Rocha Martins, Kátia Luciano Pereira Morais, Nayane Alves de Lima Galdino, Adriana Jacauna, Sálua O. C. Paula, Wagner C. S. Magalhães, Luciana W. Zuccherato, Larissa S. Campos, Paulo Guilherme O. Salles, Kenneth J. Gollob
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Cervical cancer (CC) poses a significant burden on individuals in developing regions, exhibiting heterogeneous responses to standard chemoradiation therapy, and contributing to substantial mortality rates. Unraveling host immune dynamics hol
Externí odkaz:
https://doaj.org/article/884a98d6d29d4e43a6240b25d1955f76
Autor:
Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Feodora Kostadinova, Corinne Urwyler, Verena M. Merk, Mario Noti, Israel Toja da Silva, Konstantin Bode, Fatima Nahle, Anna Pia Plazzo, Julia Koerner, Regula Stuber, Constantin Menche, Eva Karamitopoulou, Henner F. Farin, Kenneth J. Gollob, Thomas Brunner
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1545-1566 (2023)
Control of tumour development and growth by the immune system critically defines patient fate and survival. What regulates the escape of colorectal tumours from destruction by the immune system remains currently unclear. Here, we investigated the rol
Externí odkaz:
https://doaj.org/article/e2887ae1833f4172bd9bbea51ee70193
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-8 (2023)
Abstract The release of DNA to the extracellular milieu is a biological process referred to as etosis, which is involved in both physiological and pathological functions. Although the release of DNA extracellular traps (ETs) was initially attributed
Externí odkaz:
https://doaj.org/article/0c035042159b46c79239a69da193177c
Autor:
Thaiany G. Souza-Silva, Eula G. A. Neves, Carolina Koh, Andrea Teixeira-Carvalho, Silvana Silva Araújo, Maria do Carmo Pereira Nunes, Juliana de Assis Silva Gomes, Kenneth J. Gollob, Walderez Ornelas Dutra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionUnderstanding compartmentalized immune responses in target organs is crucial for elucidating the pathogenesis of various diseases. However, obtaining samples from affected vital organs often poses safety challenges. In this study, we aime
Externí odkaz:
https://doaj.org/article/9cc39431f84b49dea4010e862128d820
Autor:
Ariane F. Busso-Lopes, Leandro X. Neves, Guilherme A. Câmara, Daniela C. Granato, Marco Antônio M. Pretti, Henry Heberle, Fábio M. S. Patroni, Jamile Sá, Sami Yokoo, César Rivera, Romênia R. Domingues, Ana Gabriela C. Normando, Tatiane De Rossi, Barbara P. Mello, Nayane A. L. Galdino, Bianca A. Pauletti, Pammela A. Lacerda, André Afonso N. Rodrigues, André Luis M. Casarim, Reydson A. de Lima-Souza, Ingrid I. Damas, Fernanda V. Mariano, Kenneth J. Gollob, Tiago S. Medina, Nilva K. Cervigne, Ana Carolina Prado-Ribeiro, Thaís Bianca Brandão, Luisa L. Villa, Miyuki Uno, Mariana Boroni, Luiz Paulo Kowalski, Wilfredo Alejandro González-Arriagada, Adriana F. Paes Leme
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
The biological understanding of poor prognosis associated with lymph node metastasis in head and neck cancer (HNC) remains crucial. Here, a proteomic characterisation of 140 multisite samples from a 59-HNC patient cohort and machine learning reveals
Externí odkaz:
https://doaj.org/article/4ccd9c9167ab4e6c9dea6fe4abdd58c2
Autor:
Flávio Pignataro-Oshiro, Amanda B. Figueiredo, Nayane A. L. Galdino, Katia L. P. Morais, Walderez O. Dutra, Bianca Grassi de Miranda Silva, Diego Feriani, Flávia de Azevedo Abrantes, Ivan Leonardo Avelino França e Silva, Jayr Schmidt Filho, Juliana Valéria de Souza Framil, Marcelle Goldner Cesca, Rachel Simões Pimenta Riechelmann, Marjorie V. Batista, Kenneth J. Gollob
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionThe COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has impacted health across all sectors of society. A cytokine-release syndrome, combined with an inefficient response of innate immune cells to directly combat the virus, charac
Externí odkaz:
https://doaj.org/article/113cd73c874e4befb698029452efc7ef
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 9 (2022)
T cells recognize their ligand, the peptide major histocompatibility complex (MHC), via the T-cell receptor (TCR), which is composed of covalently linked α and β or γ and δ chains. This recognition is critical for T-cell ontogeny and controls the
Externí odkaz:
https://doaj.org/article/6d3c31fa4a464701a96476cd17f666f7
Autor:
Viviane Teixeira L. de Alencar, Amanda B. Figueiredo, Marcelo Corassa, Kenneth J. Gollob, Vladmir C. Cordeiro de Lima
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lung cancer is the second most common and the most lethal malignancy worldwide. It is estimated that lung cancer in never smokers (LCINS) accounts for 10-25% of cases, and its incidence is increasing according to recent data, although the reasons rem
Externí odkaz:
https://doaj.org/article/98f1c7adb0704679bba34893d99864bf
Autor:
Eula G. A. Neves, Carolina C. Koh, Thaiany G. Souza-Silva, Lívia Silva Araújo Passos, Ana Carolina C. Silva, Teresiama Velikkakam, Fernanda Villani, Janete Soares Coelho, Claudia Ida Brodskyn, Andrea Teixeira, Kenneth J. Gollob, Maria do Carmo P. Nunes, Walderez O. Dutra
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Chronic Chagas cardiomyopathy (CCC) is one of the deadliest cardiomyopathies known and the most severe manifestation of Chagas disease, which is caused by infection with the parasite Trypanosoma cruzi. Idiopathic dilated cardiomyopathies (IDC) are a
Externí odkaz:
https://doaj.org/article/f7782b0f1dfa4432bcdada9cfa7b6483