Zobrazeno 1 - 10
of 569
pro vyhledávání: '"J. Goldstone"'
Autor:
Michael J. Ormsby, Síle A. Johnson, Nuria Carpena, Lynsey M. Meikle, Robert J. Goldstone, Anne McIntosh, Hannah M. Wessel, Heather E. Hulme, Ceilidh C. McConnachie, James P.R. Connolly, Andrew J. Roe, Conor Hasson, Joseph Boyd, Eamonn Fitzgerald, Konstantinos Gerasimidis, Douglas Morrison, Georgina L. Hold, Richard Hansen, Daniel Walker, David G.E. Smith, Daniel M. Wall
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2297-2305.e5 (2020)
Summary: Propionic acid (PA) is a bacterium-derived intestinal antimicrobial and immune modulator used widely in food production and agriculture. Passage of Crohn’s disease-associated adherent-invasive Escherichia coli (AIEC) through a murine model
Externí odkaz:
https://doaj.org/article/c67d7647d1fe4b1ebd8cd8c4b4517135
Autor:
James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation o
Externí odkaz:
https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
Autor:
Justin J. J. van der Hooft, Robert J. Goldstone, Susan Harris, Karl E. V. Burgess, David G. E. Smith
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Since its first isolation a century ago, the gut inhabitant Escherichia coli strain Nissle 1917 has been shown to have probiotic activities; however, it is yet not fully elucidated which differential factors play key roles in its beneficial interacti
Externí odkaz:
https://doaj.org/article/3c07f394ecef40fda06c5cd2e8b55fa5
Autor:
Susan Harris, Marta J. Piotrowska, Robert J. Goldstone, Ruby Qi, Geoffrey Foster, Ulrich Dobrindt, Jean-Yves Madec, Charlotte Valat, Francesco V. Rao, David G. E. Smith
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Bacterial surface polysaccharides play significant roles in fitness and virulence. In Gram-negative bacteria such as Escherichia coli, major surface polysaccharides are lipopolysaccharide (LPS) and capsule, representing O- and K-antigens, respectivel
Externí odkaz:
https://doaj.org/article/01ea173f77324b60a623daff796a3b33
Autor:
Shlomo E. Blum, Robert J. Goldstone, James P. R. Connolly, Maryline Répérant-Ferter, Pierre Germon, Neil F. Inglis, Oleg Krifucks, Shubham Mathur, Erin Manson, Kevin Mclean, Pascal Rainard, Andrew J. Roe, Gabriel Leitner, David G. E. Smith
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Escherichia coli are major bacterial pathogens causing bovine mastitis, a disease of great economic impact on dairy production worldwide. This work aimed to study the virulence determinants of mammary pathogenic E. coli (MPEC). By whole-geno
Externí odkaz:
https://doaj.org/article/adf8534cbb094e8e93aeaeafbec91e0a
Autor:
Richard J. Goldstone
Publikováno v:
History and Hope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16180615c50c23f881ca264c20f2e6d5
https://doi.org/10.1515/9780823291779-025
https://doi.org/10.1515/9780823291779-025
Autor:
Richard J. Goldstone
Publikováno v:
Constitutionalizing Transitional Justice ISBN: 9780429505089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6af1cb0ffab7e62012a6dd1d8e542f7
https://doi.org/10.4324/9780429505089-3
https://doi.org/10.4324/9780429505089-3
Autor:
Richard J. Goldstone
Throughout his career, the distinguished South African jurist Richard J. Goldstone has been deeply committed to promoting human rights in his own country and abroad. A justice of the Constitutional Court of South Africa since 1994, he has also served
Autor:
James P R Connolly, Mads Gabrielsen, Robert J Goldstone, Rhys Grinter, Dai Wang, Richard J Cogdell, Daniel Walker, David G E Smith, Andrew J Roe
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005359 (2016)
The ability of any organism to sense and respond to challenges presented in the environment is critically important for promoting or restricting colonization of specific sites. Recent work has demonstrated that the host metabolite D-serine has the ab
Externí odkaz:
https://doaj.org/article/1dc284a719ef49db90922620316798bb
Autor:
Christopher J. Neill, Humphrey H. P. Yiu, Elizabeth C. H. T. Lau, Theodore B. Henry, David Smith, Robert J. Goldstone, Susan Harris
Publikováno v:
ACS Infectious Diseases. 6:2959-2969
The continued emergence and spread of antimicrobial resistance (AMR), particularly multidrug resistant (MDR) bacteria, are increasing threats driving the search for additional and alternative antimicrobial agents. The World Health Organization (WHO)