Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J. Gerardo Valadez"'
Autor:
Sabyasachi Das, Thomas Boehm, Stephen J. Holland, Jonathan P. Rast, Francisco Fontenla-Iglesias, Ryo Morimoto, J. Gerardo Valadez, Ryan D. Heimroth, Masayuki Hirano, Max D. Cooper
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112933- (2023)
Summary: Jawless vertebrates possess an alternative adaptive immune system in which antigens are recognized by variable lymphocyte receptors (VLRs) generated by combinatorial assembly of leucine-rich repeat (LRR) cassettes. Three types of receptors,
Externí odkaz:
https://doaj.org/article/5193eaf2017c4327afa7d5ab3268014c
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21353 (2011)
Sonic hedgehog (Shh) signaling regulates cell growth during embryonic development, tissue homeostasis and tumorigenesis. Concentration-dependent cellular responses to secreted Shh protein are essential for tissue patterning. Shh ligand is covalently
Externí odkaz:
https://doaj.org/article/66e5a8e8899345b58fb537dde9b85ad4
Autor:
Vandana K. Grover, Melissa D. Carter, Michael K. Cooper, Sunday A. Abiria, Thomas V. Williams, J. Gerardo Valadez, Christopher J. Lundberg, M. Wade Calcutt
Publikováno v:
Cancer Letters. 328:297-306
The Hedgehog (Hh) pathway regulates the growth of a subset of adult gliomas and better definition of Hh-responsive subtypes could enhance the clinical utility of monitoring and targeting this pathway in patients. Somatic mutations of the isocitrate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca317230a58b35d87521c3f19c31980
https://doi.org/10.1016/j.canlet.2012.10.002
https://doi.org/10.1016/j.canlet.2012.10.002
Autor:
Ty W. Abel, Charles B. Stevenson, Kathryn M. McMillan, Ronald R. Price, Michael L. Edgeworth, Khubaib Y. Mapara, J. Gerardo Valadez, Reid C. Thompson, Moneeb Ehtesham
Publikováno v:
Neurosurgery. 63:560-570
Gliomas are the most common type of primary brain tumor and, according to the World Health Organization convention, are divided into four clinical grades (I–IV) on the basis of tumor histopathology (11). Grade I tumors represent a distinct subset o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d2b5d95bf40bb34f82388ee672a1b2
https://doi.org/10.1227/01.neu.0000324896.26088.ef
https://doi.org/10.1227/01.neu.0000324896.26088.ef
Publikováno v:
Chemical Research in Toxicology. 17:972-982
O(6)-Alkylguanine DNA-alkyl transferase (AGT) has been shown to conjugate both 1,2-dibromoethane and dibromomethane, yielding AGT inactivation, DNA-AGT cross-linking, and enhanced mutagenicity. A variety of related chemicals were examined to determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0487d0f4618a069027bcbb767e278eca
https://doi.org/10.1021/tx049897u
https://doi.org/10.1021/tx049897u
Publikováno v:
Journal of Biological Chemistry. 279:13435-13446
Several steps occur between the reaction of a chemical with DNA and a mutation, and each may influence the resulting mutation spectrum, i.e. nucleotides at which the mutations occur. The half-mustard S-(2-bro-moethyl)glutathione is the reactive conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f23971aecf740136149084692d72304
https://doi.org/10.1074/jbc.m312358200
https://doi.org/10.1074/jbc.m312358200
Autor:
Vandana K. Grover, Alexander L. Munden, Michael K. Cooper, J. Gerardo Valadez, Sunday A. Abiria, Thomas V. Williams, Christopher J. Lundberg, Ato Wallace
Hedgehog (Hh) signaling regulates the growth of malignant gliomas by a ligand-dependent mechanism. The cellular source of Sonic Hh ligand and mode of signaling have not been clearly defined due to the lack of methods to definitively identify neoplast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3ce2860a7f2c9949cc08d8bb367a69
https://europepmc.org/articles/PMC4290668/
https://europepmc.org/articles/PMC4290668/
Autor:
Niveditha Krishna, Michelle Fournier, Prakash Chinnaiyan, Philip A. Barker, Samuel Lawn, Michele Zeinieh, J. Gerardo Valadez, Geoffrey T. Gibney, Lisa Potthast, David Fenstermacher, Bruce D. Carter, Michael K. Cooper, Rajappa S. Kenchappa, Peter A. Forsyth, Xiaotao Qu
Publikováno v:
The Journal of biological chemistry. 289(12)
Malignant gliomas are highly invasive, proliferative, and resistant to treatment. Previously, we have shown that p75 neurotrophin receptor (p75NTR) is a novel mediator of invasion of human glioma cells. However, the role of p75NTR in glioma prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc3d1c828f3fb53b91c5aa447ebfdb3
https://pubmed.ncbi.nlm.nih.gov/24519935
https://pubmed.ncbi.nlm.nih.gov/24519935
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21353 (2011)
PLoS ONE
PLoS ONE
Background Sonic hedgehog (Shh) signaling regulates cell growth during embryonic development, tissue homeostasis and tumorigenesis. Concentration-dependent cellular responses to secreted Shh protein are essential for tissue patterning. Shh ligand is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32cb2d9e517d38c198b971580ffba46
http://europepmc.org/articles/PMC3128587?pdf=render
http://europepmc.org/articles/PMC3128587?pdf=render
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.