Zobrazeno 1 - 10
of 123
pro vyhledávání: '"J. Gawler"'
Autor:
Dennis Wray, D. J. Gawler, Hugh A. Pearson, V A Porter, Nigel Hodson, Carol J. Milligan, Lin-Hua Jiang
Publikováno v:
Journal of Biological Chemistry. 275:6135-6143
We have studied the effect of 8-bromo-cyclic GMP (8-Br-cGMP) on cloned cardiac L-type calcium channel currents to determine the site and mechanism of action underlying the functional effect. Rabbit cardiac alpha(1C) subunit, in the presence or absenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fac391ffe3ee902a02ff33fb6d2d36
https://doi.org/10.1074/jbc.275.9.6135
https://doi.org/10.1074/jbc.275.9.6135
Autor:
Andrew Chow, Debra J Gawler
Publikováno v:
FEBS Letters. 460:166-172
Annexin VI is a Ca2+-dependent membrane and phospholipid binding protein. It mediates a protein-protein interaction with the Ras p21 regulatory protein p120GAP. In this study we have mapped the binding site of GAP within the annexin VI protein. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2848e19bfe1cae35a06f593b641c54c0
https://doi.org/10.1016/s0014-5793(99)01336-8
https://doi.org/10.1016/s0014-5793(99)01336-8
Autor:
Denise Kendrick, Hannah Carpenter, Richard W Morris, Dawn A Skelton, Heather Gage, Ann Bowling, Tahir Masud, Zoe Stevens, Mirilee Pearl, Sheena J Gawler, Arun Kumar, Steve Iliffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009cb2db4162b597c7a59610b68fc252
https://doi.org/10.1002/14651858.cd009848
https://doi.org/10.1002/14651858.cd009848
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 56:977-981
Three siblings presented with a progressive neurological disorder beginning in the third decade of life and characterised by palatal myoclonus, nystagmus, bulbar weakness and spastic tetraparesis. There was no evidence of intellectual deterioration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9247ee40ee730ab9716a7ef499b2ae0a
https://doi.org/10.1136/jnnp.56.9.977
https://doi.org/10.1136/jnnp.56.9.977
Publikováno v:
Biochemical Journal. 272:519-524
Inositol-polyphosphate-induced Ca2+ mobilization was investigated in saponin-permeabilized SH-SY5Y human neuroblastoma cells. Ins(1,4,5)P3 induced a dose-related release from intracellular Ca2+ stores with an EC50 (concn. giving half-maximal effect)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4edd31f7c5179e099415f18c96c3e5a
https://doi.org/10.1042/bj2720519
https://doi.org/10.1042/bj2720519
Publikováno v:
Neurology. 66(9)
A 58-year-old woman developed painful toes while under investigation for dyspnea. She was anemic with vitamin B12 and iron deficiency and replacement therapy was instituted. She had undergone partial gastrectomy 20 years previously for peptic ulcer d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f831bb756e34990a38ade89c7cef7878
https://pubmed.ncbi.nlm.nih.gov/16682688
https://pubmed.ncbi.nlm.nih.gov/16682688
Publikováno v:
Journal of clinical pathology. 58(9)
This report describes the case of a 54 year old woman with very severe aplastic anaemia who was treated with antilymphocyte globulin (ALG) and developed Guillain Barre syndrome (GBS). No antecedent infective aetiology was identified. Although there a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6c577231bf42ecd4a079982b799068
https://pubmed.ncbi.nlm.nih.gov/16126887
https://pubmed.ncbi.nlm.nih.gov/16126887
Autor:
T. A. Lister, J. Goldin, P. Domizio, K. Nagendran, A. Z. S. Rohatiner, J. Fearnley, J. Gawler, Peter Johnson
Publikováno v:
British Journal of Cancer
Fludarabine is a comparatively new drug for the treatment of low-grade lymphoid malignancy. This report describes five cases of unusual neurological illnesses occurring after treatment with fludarabine. These suggest that caution should be exercised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7fa2e152e76172f61d101aa30c6b0a
https://doi.org/10.1038/bjc.1994.430
https://doi.org/10.1038/bjc.1994.430
Publikováno v:
FEBS letters. 469(1)
p120GAP (RasGAP) has been proposed to function as both an inhibitor and effector of Ras. Previously we have shown that RasGAP contains a C2 domain which mediates both Ca2+-dependent membrane association and protein–protein interactions. Specificall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2513593d82854572b65a1d64c27ffc
https://pubmed.ncbi.nlm.nih.gov/10708762
https://pubmed.ncbi.nlm.nih.gov/10708762
Publikováno v:
Cellular signalling. 11(6)
The GTPase activating protein, p120GAP, contains an amino acid sequence motif called the Ca2+-dependent lipid binding domain (CaLB) which mediates a protein–protein interaction between p120GAP and annexin VI and also binds to negatively charged pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f481c30ef6232ab1c4df36207026c1f1
https://pubmed.ncbi.nlm.nih.gov/10400317
https://pubmed.ncbi.nlm.nih.gov/10400317