Zobrazeno 1 - 10
of 38
pro vyhledávání: '"J. Ganzhorn"'
Autor:
J. Ganzhorn, P.M. Kappeler
The past decade has seen a steady increase in studies oflemur behavior and ecology. As a result, there is much novel information on newly studied populations, and even newly discovered species, that has not yet been published or summarized. In fact,
Autor:
Tatiana Smirnova, Nigel J. Cairns, Axel J. Ganzhorn, Claude Sauvage, Danielle Duverger, Veronique Laucher, David J. Cowley, Sylviane Boularand, Jean-Pierre Ledig, Alexandra Carreau, Vladimir Saudek, Blanche Heintzelmann, Chantal Guenet, Annie Bernhardt, Michael Teufel, C.J. Carter
Publikováno v:
Journal of Biological Chemistry. 278:6521-6531
Carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyric acid-L-histidine) are two naturally occurring dipeptides with potential neuroprotective and neurotransmitter functions in the brain. Peptidase activities degrading both carnosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9c30dea732ab3ff794ef423654b338
https://doi.org/10.1074/jbc.m209764200
https://doi.org/10.1074/jbc.m209764200
Over the course of the past decade, there has been an enormous augmentation in the amount of information available on the lemurs of Madagascar. These advances are closely coupled with an increase in the number of national and international researcher
Autor:
Axel J. Ganzhorn, Frank Bolkenius
Publikováno v:
General Pharmacology: The Vascular System. 31:655-659
1. Peptidylglycine alpha-amidating mono-oxygenase (PAM) is a bifunctional key enzyme in the bioactivation of neuropeptides. Its biosynthesis, distribution, functional role, and pharmacological manipulation are discussed. 2. PAM biosynthesis from a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7553f496ab0208c9527e984652aa4cbe
https://doi.org/10.1016/s0306-3623(98)00192-x
https://doi.org/10.1016/s0306-3623(98)00192-x
Autor:
Axel J. Ganzhorn, Jan Hoflack, Marie-Christine Chanal, Serge R. Piettre, Françoise Strasser, Patricia D. Pelton
Publikováno v:
Bioorganic & Medicinal Chemistry. 6:1865-1874
alpha-Hydroxyphosphonates are moderately potent (Ki = 6-600 microM) inhibitors of the enzyme myo-inositol monophosphatase (McLeod et al., Med. Chem. Res. 1992, 2, 96). Hydroxy-[4-(5,6,7,8-tetrahydronaphtyl-1-oxy)phenyl]methyl phosphonate (3) was resy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f849872347bc64cd9ecd63570144a
https://doi.org/10.1016/s0968-0896(98)00148-5
https://doi.org/10.1016/s0968-0896(98)00148-5
Autor:
Jean-Bernard Ducep, Axel J. Ganzhorn, François Piriou, Jean-Michel Rondeau, Serge R. Piettre, Charles G. Schelcher, Brigitte Lesur, Catherine André, Marie-Christine Chanal, Pierre Jean-Marie Bernard Raboisson, Pascale Zimmermann
Publikováno v:
Journal of Medicinal Chemistry. 40:4208-4221
The first successful preparation of mono- and disubstituted 3,7-dihydroxytropolone involves a four-step synthetic scheme. Thus, bromination of 3,7-dihydroxytropolone (8) followed by permethylation of the resultant products furnished gram quantities o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14180313cd3759ddeb2e624efd220a35
https://doi.org/10.1021/jm9701942
https://doi.org/10.1021/jm9701942
Autor:
J.M Seiler, J Ganzhorn
Publikováno v:
Nuclear Engineering and Design. 178:259-268
A new deterministic methodology is proposed for the calculation of viscosities of well stirred corium-concrete mixtures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f37229dfee69b99f6977fcdb3aa699
https://doi.org/10.1016/s0029-5493(97)00232-x
https://doi.org/10.1016/s0029-5493(97)00232-x
Publikováno v:
Journal of the American Chemical Society. 119:3201-3204
Mono- and polyhydroxytropolones are potent competitive inhibitors of inositol monophosphatase. Modeling studies indicate that this inhibition occurs most probably through a novel mode of action involving the chelation of the two magnesium ions in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::314d41f702328f89af829ffff816f016
https://doi.org/10.1021/ja9634278
https://doi.org/10.1021/ja9634278
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:393-396
Several unsaturated thioacetic acids were synthesized as potential mechanism-based inhibitors of peptidyglycine α-hydroxylating monooxygenase (PHM) prepared from horse serum. Trans-styrylthioacetic acid produced potent time-dependent inhibition of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::149b54ff1385e2bcd00e0ca13bff4a95
https://doi.org/10.1016/0960-894x(96)00041-8
https://doi.org/10.1016/0960-894x(96)00041-8
Publikováno v:
European Journal of Biochemistry. 221:581-593
The structure of cGMP-dependent protein kinase I alpha-(546-576)-peptide amide (peptide-546) and its effects on cGMP-dependent protein kinase I alpha (G-kinase) have been studied. By primary sequence analysis and analogy to a peptide that stimulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2972de9573b719465f1e5d370b44f05c
https://doi.org/10.1111/j.1432-1033.1994.tb18770.x
https://doi.org/10.1111/j.1432-1033.1994.tb18770.x