EEG pre-burst suppression: characterization and inverse association with preoperative cognitive function in older adults

Autor: Melody Reese, Soren Christensen, Harel Anolick, Kenneth C. Roberts, Megan K. Wong, Mary Cooter Wright, Leah Acker, Jeffrey N. Browndyke, Marty G. Woldorff, Miles Berger, the MADCO-PC and INTUIT Investigators, O Akinyemi, CL Amundsen, P Avasarala, M Barber, R Beach, S Bengali, E Bennett, A Berchuck, MF Berry, DG Blazer, MP Bolognesi, R Brassard, BE Brigman, JN Browndyke, M Bullock, T Bunning, A Burke, V Cai, J Carter, J Chapman, C Chen, V Cheong, S Christensen, HJ Cohen, B Colin, C Colon-Emeric, M Cooter, M Cox, D Crabtree, B Davidson, JK DeOrio, M Devinney, TA D’Amico, ME Easley, E Ehieli, T Ellett, D Erdmann, RM Esclamado, M Ferrandino, B Funk, J Gadsden, J Gardner, G Garrigues, C Giattino, DT Gold, S Grant, R Greenup, J Guercio, DK Gupta, A Habib, RK Hallows, DH Harpole, SM Harris, MG Hartwig, L Havrilesky, T Henley, C Holland, ST Hollenbeck, J Hu, R Huang, E Iboaya, BA Inman, DW Jang, J Kaisen, A Kawasaki, A Khan, J Klapper, S Lagoo-Deenadayalan, DT Laskowitz, PS Lee, WT Lee, J Lemm, H Levinson, ME Lipkin, H Litchfield, CR Mantyh, E Marlor, KT Martucci, J Mathew, C Maxwell, DL McDonagh, J Migaly, SK Mithani, E Moretti, P Mosca, J Moul, D Murdoch, MF Newman, K Ni, T Novick, B Ohlendorf, S Olson, MW Onaitis, D Oyeyemi, TN Pappas, GL Pellom, AN Perez, AC Peterson, A Podgoreanu, TJ Polascik, P Potash, GM Preminger, R Previs, Q Quinones, EN Rampersaud, A Ray, A Renne, K Roberts, CN Robertson, SA Roman, S Runyon, E Sanders, A Sandler, F Sbahi, CD Scales, RP Scheri, K Seymour, S Smani, SK Smith, M Stang, S Stanley, K Sweeney, A Syed, A Szydlowska, L Talbot, N Terrando, JKM Thacker, J Thomas, BC Tong, Y Toulgoat-Dubois, A Tu, SN Vaslef, N Waldron, X Wang, DS Warner, K Weinhold, SS Wellman, H Whitson, T Wickenheisser, D Williams, M Woldorff, MK Wong, C Young, S Zani

Publikováno v: Frontiers in Aging Neuroscience, Vol 15 (2023)

The most common complication in older surgical patients is postoperative delirium (POD). POD is associated with preoperative cognitive impairment and longer durations of intraoperative burst suppression (BSup) – electroencephalography (EEG) with re

Externí odkaz: https://doaj.org/article/93500dbf0366414a890d2a69aa098aea

The failed peripheral nerve block

Autor: T. Bottomley, J. Gadsden, S. West

Publikováno v: BJA Education. 23:92-100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd5817d66a4a9b93cc3e954016116cfa
https://doi.org/10.1016/j.bjae.2022.12.002

Data from Palbociclib Renders Human Papilloma Virus–Negative Head and Neck Squamous Cell Carcinoma Vulnerable to the Senolytic Agent Navitoclax

Autor: Thomas J. Ow, Evripidis Gavathiotis, Nicolas F. Schlecht, Michael B. Prystowsky, Jeffrey E. Segall, Carlos Thomas, Nitisha Shrivastava, Daniel Li, Cory D. Fulcher, Nicholas J. Gadsden

We demonstrate that inhibition of cyclin-dependent kinases 4/6 (CDK4/6) leads to senescence in human papillomavirus (HPV)–negative (−) head and neck squamous cell carcinoma (HNSCC), but not in HPV-positive (+) HNSCC. The BCL-2 family inhibitor, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::896459acd41aaf17a9d8d7884ff25ec6
https://doi.org/10.1158/1541-7786.c.6544985.v1

Supplementary Video: HPV+ (UMSCC47) from Palbociclib Renders Human Papilloma Virus–Negative Head and Neck Squamous Cell Carcinoma Vulnerable to the Senolytic Agent Navitoclax

Autor: Thomas J. Ow, Evripidis Gavathiotis, Nicolas F. Schlecht, Michael B. Prystowsky, Jeffrey E. Segall, Carlos Thomas, Nitisha Shrivastava, Daniel Li, Cory D. Fulcher, Nicholas J. Gadsden

Supplementary Video: HPV+ (UMSCC47) is a time-lapse video illustrating a HPV+ cell line's response to palbociclib treatment.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c04a109cf7851a0cd6047ed4218ca9
https://doi.org/10.1158/1541-7786.22526018

Palbociclib Renders Human Papilloma Virus–Negative Head and Neck Squamous Cell Carcinoma Vulnerable to the Senolytic Agent Navitoclax

Autor: Cory D. Fulcher, Michael B. Prystowsky, Nicholas J. Gadsden, Nitisha Shrivastava, Thomas J. Ow, Daniel Li, Nicolas F. Schlecht, Jeffrey E. Segall, Evripidis Gavathiotis, Carlos Thomas

Publikováno v: Mol Cancer Res

We demonstrate that inhibition of cyclin-dependent kinases 4/6 (CDK4/6) leads to senescence in human papillomavirus (HPV)–negative (−) head and neck squamous cell carcinoma (HNSCC), but not in HPV-positive (+) HNSCC. The BCL-2 family inhibitor, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676ab0741f9ad95f9cbb434311b853fe
https://doi.org/10.1158/1541-7786.mcr-20-0915