Zobrazeno 1 - 10
of 99
pro vyhledávání: '"J. Gaddie"'
Autor:
Terence L. Kirley, Keith J. Gaddie
Publikováno v:
Biochemistry. 48:9437-9447
Polar residues play essential roles in the functions of transmembrane helices by mediating and stabilizing their helical interactions. To investigate the structural and functional roles of the conserved polar residues in the N- and C-terminal transme
Publikováno v:
Archives of Biochemistry and Biophysics. 457:7-15
Nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) is a cell surface, membrane-bound enzyme that hydrolyzes extracellular nucleotides, thereby modulating purinergic signaling. An alternatively spliced variant of NTPDase3 was obtained and analyze
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Autor:
Terence L. Kirley, Keith J. Gaddie
Publikováno v:
Purinergic signalling. 6(3)
The active sites of the membrane-bound nucleoside triphosphate diphosphohydrolases (NTPDases) regulate and are regulated by coordinated and spatially distant movements of their transmembrane helices, modulating enzyme activity, and substrate specific
Autor:
A, Langlands, R, Dowdle, A, Elliott, J, Gaddie, A, Graham, G, Johnson, S, Lam, A, McGowan, P, McNamee, J, Morrison, T, Murphy, K, Reynard, P, Rudge, J, Trueland
Publikováno v:
British journal of hospital medicine (London, England : 2005). 70(1 Suppl 1)
Publikováno v:
Scopus-Elsevier
We describe a patient who developed pulmonary nocardiosis whilst taking long term oral steroids for asthma. Nocardiosis is more common than is generally appreciated by clinicians, is notoriously difficult to diagnose, and is associated with significa
Effect of prednisolone on theophylline pharmacokinetics in patients with chronic airflow obstruction
Publikováno v:
Thorax. 42:195-198
The effect of prednisolone on the elimination kinetics of theophylline was studied in a group of nine patients with chronic airflow obstruction. Volume of distribution, plasma half life, and clearance after a single intravenous dose of aminophylline
Publikováno v:
British Journal of Clinical Pharmacology. 2:263-266
1 In a double-blind placebo controlled dose-response experiment in six asthmatic patients with reversible airways obstruction the effect of i.m. salbutamol (4 mug/kg, 8 mug/kg or 12 mug/kg) was assessed by improvement in spirometry and change in puls
Publikováno v:
British Journal of Diseases of the Chest. 66:141-146
Histamine induced bronchoconstriction was significantly reduced in 6 patients with extrinsic bronchial asthma by thymoxamine, a specific α-adrenergic 3 . Mean pulse rate and blood pressure in 6 asthmatic patients after intravenous thymoxamine (0 ·
Publikováno v:
Journal of Infection. 5:216-218