Zobrazeno 1 - 10
of 73
pro vyhledávání: '"J. GORDON LINDSAY"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123303 (2015)
Mitochondrial 2-cys peroxiredoxin III (PrxIII) is a key player in antioxidant defence reducing locally-generated H2O2 to H2O. A Phe to Leu (F190L) mutation in the C-terminal α-helix of PrxIII, mimicking that found in some bacteria and parasites, inc
Externí odkaz:
https://doaj.org/article/d08e62a3e68348fca87f2caf161d1dd7
Publikováno v:
Journal of Molecular Biology. 372:1022-1033
The mitochondrial 2-Cys peroxiredoxin PrxIII serves as a thioredoxin-dependent peroxidase operating in tandem with its cognate partners, an organelle-specific thioredoxin (Trx2) and NADP-linked thioredoxin reductase (TRR2). This PrxIII pathway is eme
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0123303 (2015)
PLoS ONE, Vol 10, Iss 4, p e0123303 (2015)
Mitochondrial 2-cys peroxiredoxin III (PrxIII) is a key player in antioxidant defence reducing locally-generated H2O2 to H2O. A Phe to Leu (F190L) mutation in the C-terminal α-helix of PrxIII, mimicking that found in some bacteria and parasites, inc
Autor:
Arne Schousboe, J. Gordon Lindsay, Helle S. Waagepetersen, Gary E. Gibson, Gert H. Hansen, Kirsten Fenger
Publikováno v:
Glia. 53:225-231
In brain cells, various metabolites and metabolic pathways, largely of mitochondrial origin, have been shown to be compartmentalized. Attention has therefore been focused on the possible existence of mitochondrial heterogeneity in the brain at the ce
Publikováno v:
Antioxidants & Redox Signaling. 5:517-527
4-hydroxynonenal (HNE), a product of omega-6 polyunsaturated fatty acid peroxidation, impairs mitochondrial respiration in vitro by adducting the alpha-ketoglutarate dehydrogenase complex (KGDC) and inhibiting its activity. The present study seeks to
Publikováno v:
Journal of Biological Chemistry. 278:32631-32637
Bovine mitochondrial SP-22 is a member of the peroxiredoxin family of peroxidases. It belongs to the peroxiredoxin 2-Cys subgroup containing three cysteines at positions 47, 66, and 168. The cloning and overexpression in Escherichia coli of recombina
Autor:
Richard J. Cogdell, J. Gordon Lindsay
Publikováno v:
New Phytologist. 145:167-196
Summary 167 I. INTRODUCTION 168 II. THE IMPACT OF PROTEIN STRUCTURAL INFORMATION ON THE UNDERSTANDING OF THE PRIMARY REACTIONS IN PHOTOSYNTHESIS 169 1. The structure of the purple bacterial reaction centre 170 2. The structure of PSI 172 3. The struc
Autor:
Richard J. Cogdell, J. Gordon Lindsay
Publikováno v:
Trends in Biotechnology. 16:521-527
The primary photochemical reactions in purple-bacterial photosynthesis take place in discrete, membrane-bound pigment–protein complexes called reaction centres and light-harvesting complexes. The detailed information on their structure and function
Autor:
Andrew W. Munro, J. Gordon Lindsay
Publikováno v:
Molecular Microbiology. 20:1115-1125
The cytochromes P-450 (P-450s) constitute an extremely large family ('superfamily') of haemoproteins that catalyse the oxidation of a wide range of physiological and non-physiological compounds. A remarkable feature of the P-450s is the manipulation
Publikováno v:
Annals of Neurology. 39:592-598
To determine whether the reduction in brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease (AD) is associated with an abnormality in one of its three constituent enzyme subunits, we measured protein levels of alpha-ketoglut