Zobrazeno 1 - 10
of 41
pro vyhledávání: '"J. GEORGE BEKESI"'
Autor:
Ashley Davis, Jian-Dong Jiang, Kim M. Middleton, Yue Wang, Imre Weisz, Yi-He Ling, J. George Bekesi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 6, Pp 498-507 (1999)
It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis 1]. In this report, we challenge the
Externí odkaz:
https://doaj.org/article/a50b2ecb1bf943a38df1ca3817ae2a9c
Autor:
Julia P. Roboz, Larry Denner, Michael Schlesinger, James F. Holland, J. George Bekesi, Jian Dong Jiang, Yi He Ling
Publikováno v:
Biochemical Pharmacology. 60:1693-1702
The mechanism underlying the cancericidal activity of 3-m-bromoacetylamino benzoic acid ethyl ester (3-BAABE) was investigated. 3-BAABE exerted a strong cancericidal effect on human leukemia and lymphoma cells (IC(50)0.2 microgram/mL) and on cell lin
Autor:
Imre Weisz, Yue Wang, J. George Bekesi, Yi-He Ling, Ashley Davis, Kim Middleton, Jian-Dong Jiang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 6, Pp 498-507 (1999)
It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis 1]. In this report, we challenge the
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:3241-3244
Sixteen new and one known unsymmetrical open-chain diacylamines were synthesized by sodium methoxide catalyzed acylation of amides with carboxylic esters and acylamino-carboxylic esters, or acylureas with acylamino-carboxylic esters and alpha-amino a
Publikováno v:
Tetrahedron Letters. 37:563-566
l -prolyl- l -m-[bis(chloroethyl)amino]-phenylalanyl- l -norvaline ethyl ester hydrochloride, 4 (and its 3 H and 14 C doublylabeled version) was synthesized starting with reacting unprotected l -m-sarcolysin, 1 , with TFA-Pro-Cl in an acidic system t
Autor:
Jian Dong Jiang, Tsang Ph, Julia P. Roboz, Jiin-Chyuan J Luo, J. George Bekesi, Alf Fischbein
Publikováno v:
Clinical Immunology and Immunopathology. 66:163-168
To study the immunological effects of low-level occupational exposure to lead, we have examined the phenotypic parameters and functional integrity of peripheral blood lymphocytes in a group of firearms instructors and compared the data to those obtai
Publikováno v:
ChemInform. 30
Sixteen new and one known unsymmetrical open-chain diacylamines were synthesized by sodium methoxide catalyzed acylation of amides with carboxylic esters and acylamino-carboxylic esters, or acylureas with acylamino-carboxylic esters and α-amino acid
Autor:
Joyce Carafa, Yagi Mj, Fo-Nian Chu, J. George Bekesi, Jian Dong Jiang, Patricia Mason, Yuan Liu, Joyce I. Wallace
Publikováno v:
Clinical Immunology and Immunopathology. 63:126-134
Increases in plasma levels of soluble CD8 (SCD8) antigen and expansion of the CD8+ CD38+ lymphocyte compartment were early immunologic alterations frequently observed prior to detection of antibodies against human immunodeficiency virus type 1 (HIV-1
Publikováno v:
Cellular immunology. 125(1)
The kinetics of HIV-1 infection were compared among human B (DK), promonocyte (U937), T-B hybrid (CEMX174), and T (H9) cell lines. Just like H9 cells, CEMX174 cells exhibited strong syncytia induction capacity against highly HIV-1-sensitive CD4+ T ce