Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J. G. Stone"'
Approximately 13% of colorectal cancers display microsatellite instability (MSI), a form of replication error repair. Colorectal cancers developing in individuals with constitutional defects in the mismatch repair (MMR) genes hMLH1, hMSH2, hPMS1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851032ffcfd6f0e13e37bf84146cfb71
https://ora.ox.ac.uk/objects/uuid:b5ac98b2-28ce-4121-a502-6653385a46b8
https://ora.ox.ac.uk/objects/uuid:b5ac98b2-28ce-4121-a502-6653385a46b8
Publikováno v:
British Journal of Cancer
Bcl10 is a recently identified gene reported to be involved commonly in human malignancy (Willis et al (1999) Cell 96: 1–20). To investigate whether it is frequently mutated in colorectal cancer we have analysed a series of 132 colorectal cancers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896223919814ed028de3f72b42af7830
https://ora.ox.ac.uk/objects/uuid:6c1cd802-e2c2-46a6-b790-ebdcc3b14375
https://ora.ox.ac.uk/objects/uuid:6c1cd802-e2c2-46a6-b790-ebdcc3b14375
Publikováno v:
Cancer Genetics and Cytogenetics. 145:70-73
A susceptibility gene to colorectal adenomas and carcinoma (CRAC1) on chromosome region 15q14 approximately q22 has been proposed on the basis of linkage in a single family. Allele-specific loss of heterozygosity (LOH) in tumors of affected family me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca344ebdd0287df26d76552e588de6d0
https://doi.org/10.1016/s0165-4608(02)00941-x
https://doi.org/10.1016/s0165-4608(02)00941-x
Autor:
Richard S. Houlston, A Marossy, Barry A. Gusterson, A McKinna, Glen T. Coleman, A Ward, A Nash, Roger A'Hern, J G Stone, Michael R. Stratton, Sunil R. Lakhani
Publikováno v:
ResearcherID
Lobular carcinoma in situ (LCIS) is an unusual histological pattern of non-invasive neoplastic disease of the breast occurring predominantly in women aged between 40 and 50 years. LCIS is frequently multicentric and bilateral suggesting a genetic bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961504247d625f56e0572c5c4c64a0d7
https://doi.org/10.1016/s0304-3835(01)00448-7
https://doi.org/10.1016/s0304-3835(01)00448-7
Publikováno v:
Journal of Clinical Pathology. 54:484-487
Colorectal cancers with DNA mismatch repair (MMR) gene mutations characteristically display a high rate of replication errors in simple repetitive sequences detectable as microsatellite instability (MSI). Most are the result of somatic MMR dysfunctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f2a1d3d4729f77069b7d414297c752
https://doi.org/10.1136/jcp.54.6.484
https://doi.org/10.1136/jcp.54.6.484
Autor:
Julian Peto, Richard S. Houlston, J G Stone, Sanjay Popat, Ian M. Frayling, Gary Coleman, Gill Marshall
Publikováno v:
Cancer Letters. 149:203-206
The notion that some common variants of APC might confer an increased colorectal tumour risk is supported by studies of the I1307K polymorphism. Recently it has been proposed that the E1317Q variant is also associated with an increased risk. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c20f04e98ba37d94b725ef2f567cae
https://doi.org/10.1016/s0304-3835(99)00360-2
https://doi.org/10.1016/s0304-3835(99)00360-2
Autor:
J G Stone, Kristy Z. Baker, William L. Young, Christopher J. Baker, Abraham Kader, Robert A. Solomon
Publikováno v:
Anesthesiology. 81:361-367
Despite enthusiasm for the use of mild hypothermia during neurosurgical procedures, this therapy has not been evaluated systematically. This study examined the feasibility and safety of deliberate mild hypothermia and rewarming.Thirty patients schedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52cee0d09c2483058f9342b05698665
https://doi.org/10.1097/00000542-199408000-00014
https://doi.org/10.1097/00000542-199408000-00014
Publikováno v:
[1990] Proceedings of the Twelfth Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
This report describes ECG electrical interference present during extracorporeal perfusion for cardiac surgery, specifically under atmospheric conditions of low relative humidity. This interference was traced to an interaction between the polyvinyl ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4cdd9e2f8dc4c7686623560b26ff3c9
https://doi.org/10.1109/iembs.1990.692127
https://doi.org/10.1109/iembs.1990.692127
Autor:
Douglas F. Easton, N Hearle, Jane Humphreys, Bertil Damato, Helen Green, Richard S. Houlston, Julie A. Wixey, J G Stone
Publikováno v:
Investigative ophthalmologyvisual science. 44(2)
Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma. PURPOSE. Reports suggest that a subset of uveal melanoma is familial. The association of uveal melanoma with breast and ovarian cancer and the increased risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1898e6afb995b4844d8cbe330c98e81c
https://pubmed.ncbi.nlm.nih.gov/12556369
https://pubmed.ncbi.nlm.nih.gov/12556369
Autor:
Victoria Murday, J G Stone, Richard S. Houlston, Nayanta Sodha, Rosalind A. Eeles, Eamonn Sheriden
Publikováno v:
Cancer letters. 147(1-2)
The Li-Fraumeni syndrome (LFS) is a dominant disease whose hallmark is an increased risk of breast cancers, brain tumours, sarcomas, leukaemia and adrenal carcinoma. Some, but not all LFS and Li-Fraumeni-like (LFL) families are caused by TP53 mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52d25691a8d43884fdb8e884c49cfc2
https://pubmed.ncbi.nlm.nih.gov/10660104
https://pubmed.ncbi.nlm.nih.gov/10660104