Zobrazeno 1 - 10
of 162
pro vyhledávání: '"J. G. Ratcliffe"'
Publikováno v:
Journal of Intellectual Disability Research. 22:273-275
Pituitary function studies have been carried out in eight male and eight female patients with Down's syndrome who were suspected of having hypothyroidism secondary to pituitary deficiency. In all cases, the response of Human Growth Hormone to hypogly
Autor:
R. Gibson, J. G. Ratcliffe, D. R. London, Roger Holder, R. Penn, Paul M. Stewart, Andrew Parton
Publikováno v:
Clinical Endocrinology. 36:453-458
OBJECTIVE We aimed to investigate the pattern of 24-hour ACTH and cortisol secretion in pitultary-dependent Cushing's syndrome and to evaluate the pituitary and hypothalamic contributions to the disease. PATIENTS Five women with Cushing's disease (me
Publikováno v:
The Lancet. 339:164-167
Parathyroid-hormone-related protein (PTHrP) has been implicated as a humoral mediator of hypercalcaemia in malignant disease. We have investigated the contributions of PTHrP and parathyroid hormone (PTH) to the hypercalcaemia seen in routine clinical
Publikováno v:
BMJ. 303:1506-1509
OBJECTIVE--To see whether parathyroid hormone related protein has a humoral role in breast cancer. DESIGN--Plasma concentrations and tumour expression of parathyroid hormone related protein were determined (by two site immunoradiometric assay and imm
Publikováno v:
Clinical Chemistry. 37:1781-1787
We measured parathyrin (parathyroid hormone)-related peptide (PTHRP) in plasma by three region-specific RIAs and compared them with an established two-site immunoradiometric assay (IRMA) of PTHRP1-86 in samples from control subjects and from patients
Publikováno v:
Clinical Chemistry. 37:678-685
This two-site immunoradiometric assay for human parathyrin-related protein 1-86 (PTHRP1-86) in plasma uses a mouse monoclonal antibody to PTHRP1-34 coupled to cellulose particles for immunoextraction of N-terminal immunoreactivity, and a rabbit antis
Publikováno v:
Journal of Immunological Methods. 127:109-116
The production and characterisation of 17 monoclonal antibodies to human parathyroid hormone-related protein (PTH-rP) 1-34 is described. Five of the antibodies were shown to be of high avidity (Ka 4 X 10(10)-1.9 X 10(11) L/M) and able to detect 15-10
Autor:
Nigel J Bundred, W. A. Ratcliffe, J. G. Ratcliffe, R. Edwards, J. Walls, J. M. Morrison, Roger Holder
Publikováno v:
European journal of cancer (Oxford, England : 1990). (3)
Parathyroid hormone-related protein (PTHrP) 1-86 was quantified by immunoassay in extracts of 132 breast cancers, 27 samples of normal breast tissue and four fibroadenomas. PTHrP 1-86, was detected in 68% of primary tumours (range 40-302,000 fmol/g),
Autor:
W B, Mujaji, H N, Mazhindu, Z, Gomo, H T, Marima-Matarira, C, Samuwi, T, Nyamayaro, D G, Bullock, J G, Ratcliffe
Publikováno v:
The Central African journal of medicine. 40(12)
A pilot programme for assessing laboratory performance in clinical chemistry laboratories in Zimbabwe is described (ZEQAS). Twenty four laboratories providing patient care services participated. Eight lyphilised bovine sera were distributed over one
Autor:
J G Ratcliffe, Asif Ahmed, S. Hughes, Martin J. Whittle, G Powell, W. A. Ratcliffe, S.J. Bowden, J. F. Emly
Publikováno v:
The Journal of endocrinology. 142(2)
Parathyroid hormone-related protein (PTHrP), the hypercalcaemia of malignacy factor, is expressed in the tissues of the human uteroplacental unit, including the placenta, amnion and chorion. We have used three region-specific immunoassays to quantita