Zobrazeno 1 - 10 of 28 pro vyhledávání: '"J. G. Nedrud"'
2
Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages
Autor: M P Matousek, J G Nedrud, C V Harding
Publikováno v: The Journal of Immunology. 156:4137-4145
Cholera toxin (CT) is a potent mucosal adjuvant with enhancing effects on Ag presentation, although the mechanisms of its adjuvanticity remain poorly understood. Using an in vitro Ag presentation assay, we found CT and recombinant B subunit (rCTB) to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47cd81932ab8b50fc8af6067cf5b47e9
https://doi.org/10.4049/jimmunol.156.11.4137
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3
Helicobacter pylori vaccines
Autor: J. G. Nedrud, Hazel M. Mitchell, Philip Sutton, T. G. Blanchard
This chapter discusses several candidate antigens for immunization against Helicobacter pylori, as well as various vaccine adjuvants/delivery systems and immunization routes. The mechanisms of vaccine-induced H. pylori immunity and the induction of p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6552b50fbe9ff0939083e9f62c13092
https://doi.org/10.1079/9781845935948.0167
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5
Immuno-inflammatory response to Helicobacter pylori in children
Autor: Steven J. Czinn, J. G. Nedrud, Thomas G. Blanchard, J. C. Eisenberg
Publikováno v: Helicobacter pylori ISBN: 9789401057530
Since the isolation and culture of Helicobacter pylori less than 20 years ago, the terms diffuse chronic active gastritis and multifocal atrophic gastritis have been introduced in an effort to explain the fundamental role this organism plays in the d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ebd21780eb43f603c2204595b8f6798
https://doi.org/10.1007/978-94-011-3927-4_17
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6
Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity
Autor: L C, Agren, L, Ekman, B, Löwenadler, J G, Nedrud, N Y, Lycke
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(4)
The ADP-ribosylating enterotoxins, cholera toxin (CT) and Escherichia coli heat-labile toxin, are among the most powerful immunogens and adjuvants yet described. An innate problem, however, is their strong toxic effects, largely due to their promiscu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1685b9baa5027295a81470961c579a6
https://pubmed.ncbi.nlm.nih.gov/9973526
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7
Recombinant cholera toxin B subunit is not an effective mucosal adjuvant for oral immunization of mice against Helicobacter felis
Autor: T G, Blanchard, N, Lycke, S J, Czinn, J G, Nedrud
Publikováno v: Immunology. 94(1)
Cholera toxin is a potent oral mucosal adjuvant for enteric immunization. Several studies suggest that commercial cholera toxin B subunit (cCTB; purified from holotoxin) may be an effective non-toxic alternative for oral immunization. The present stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fb4003fc6deb10b8b89787c65c10337
https://pubmed.ncbi.nlm.nih.gov/9708182
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8
Th1/Th2 lymphocyte responses in Helicobacter infections
Autor: R. Redline, Thomas G. Blanchard, S. J. Czinn, J. G. Nedrud, M. Mohammadi
Publikováno v: Helicobacter pylori ISBN: 9789401060462
Although virtually everyone who is infected with Helicobacter pylori will display chronic active gastritis, such people are generally free of other symptoms, and only a minority of infected individuals develop more severe disease and overt symptoms.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a8116164ee6f4e1d38fe9d18fbc0427
https://doi.org/10.1007/978-94-011-4882-5_13
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9
IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection
Autor: A K, Bromander, L, Ekman, M, Kopf, J G, Nedrud, N Y, Lycke
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(11)
Using IL-6-deficient (IL-6 -/-) or wild-type mice, we investigated whether IL-6 is involved in the intestinal adjuvant activity of cholera toxin (CT) and to what extent IL-6 is required for mucosal IgA responses against soluble protein Ags or live He
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::030cfd299f780a01029192e114d45f66
https://pubmed.ncbi.nlm.nih.gov/8666800
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10
Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages
Autor: M P, Matousek, J G, Nedrud, C V, Harding
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(11)
Cholera toxin (CT) is a potent mucosal adjuvant with enhancing effects on Ag presentation, although the mechanisms of its adjuvanticity remain poorly understood. Using an in vitro Ag presentation assay, we found CT and recombinant B subunit (rCTB) to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1518d37dae22c0bc35172c9ffb3c4b25
https://pubmed.ncbi.nlm.nih.gov/8666780
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