Výsledky vyhledávání - "J. G. M. Van Engelen"

Effect of coexposure to methyl ethyl ketone (MEK) on n-hexane toxicokinetics in human volunteers

Autor: W. Rebel-de Haan, Gerard J. Mulder, J. J. G. Opdam, J. G. M. Van Engelen

Publikováno v: Toxicology and Applied Pharmacology, 144, 385-395. Academic Press Inc.

In order to study the effects of methyl ethyl ketone (MEK) on the toxicokinetics of n -hexane and, in particular, the formation of 2,5-hexanedione from n -hexane in humans, volunteers were exposed to n -hexane (approx. 60 ppm, 2.4 μ m in the inhaled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebff9516e0f7334fa14376f898b8f42
https://doi.org/10.1006/taap.1997.8149

Zobrazit plný text záznamu

Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions

Autor: Elaine M. Kaptein, C T Joe, J.A.G.M. van Raaij, Theo J. Visser, J. G. M. Van Engelen, A Brouwer, K.J. van den Berg, H. Van Toor

Publikováno v: Endocrinology 133 (1993)
Endocrinology, 133, 2177-2186

We investigated the effects of in vivo treatment with different microsomal enzyme inducers, including clofibrate (CLOF), hexachlorobenzene (HCB), 3-methylcholanthrene (MC), 3,3',4,4'-tetrachlorobiphenyl (TCB), and 2,3,7,8-tetrachloro-p-dioxin, as wel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2216d93bd313aeb329641375f4ba07
https://doi.org/10.1210/endo.133.5.8404669

Zobrazit plný text záznamu

Thyroxine and 3,3′,5-Triiodothyronine Are Glucuronidated in Rat Liver by Different Uridine Diphosphate-Glucuronyltransferases*

Autor: G. Hennemann, P. Karels, A. Brouwer, Roelof Docter, H. J. Van Der Hoek, J. G. M. Van Engelen, Theo J. Visser, E.P. Krenning, J. B. Beetstra, M. De Jong

Publikováno v: Endocrinology, 128, 741-746
Endocrinology 128 (1991)

Male Wistar rats were treated with 50 mg 3,3',4,4'-tetrachlorobiphenyl (TCB)/kg BW or vehicle. After 4 days, the livers were isolated and perfused for 90 min with 2 nM [125I]T3 or 10 nM [125I]T4 in Krebs-Ringer medium containing 1% albumin. Deiodinat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0035bc7f14b5ef6b0679f1ef42d22d1
https://doi.org/10.1210/endo-128-2-741

Zobrazit plný text záznamu

Consumer exposure scenarios: development, challenges and possible solutions

Autor: Carlos Rodriguez, J G M Van Engelen, Gerhard Heinemeyer

Publikováno v: Journal of exposure scienceenvironmental epidemiology. 17

Exposure scenarios (ES) under REACH (Registration, Evaluation, and Authorisation of Chemicals; new EU legislation) aim to describe safe conditions of product and substance use. Both operational conditions and risk management measures (RMMs) are part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2ee453789d6eceb31506d007e51878
https://pubmed.ncbi.nlm.nih.gov/17505503

Zobrazit plný text záznamu

Determination of 2,5-hexanedione, a metabolite of n-hexane, in urine: evaluation and application of three analytical methods

Autor: Sanja Kezic, W. De Haan, J. G. M. Van Engelen, F. A. De Wolff, J. J. G. Opdam

Publikováno v: Journal of chromatography. B, Biomedical applications, 667(2), 233-240. Elsevier BV

Three methods for the determination of 2,5-hexanedione (2,5-HD) in urine were compared in order to assess their applicability for toxicokinetic studies and biological monitoring of occupational exposure to n-hexane. Two of them were based on derivati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7725f3584549b94ee2d353390608973
https://pubmed.ncbi.nlm.nih.gov/7663695

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání