Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J. G. Lloyd-Jones"'
Autor:
M. J. Rance, J. G. Lloyd-Jones, G. J. Dockray, R A Moore, I. R. Flockhart, M. R. D. Bennett, A. J. Bartlett
Publikováno v:
European Journal of Clinical Pharmacology. 18:339-345
Antisera to buprenorphine were obtained in rabbits immunised with 3-0-carboxymethylbuprenorphine and N-hemisuccinyl-norbuprenorphine conjugated to bovine serum albumin. Using the latter antiserum and tritium labelled buprenorphine a radioimmunoassay
Publikováno v:
Journal of Liquid Chromatography. 3:1335-1352
The use of hplc for the separation of various peptide diastereoisomers without the need for sample pre-treatment is described. The effect of the concentration of acetonitrile in the mobile phase on the retention of peptides on ODS- and Cyanopropyl-bo
Autor:
K. Waltham, C. J. Lewis, N. C. Muir, J. G. Lloyd-Jones, M. A. McCleavy, M. E. Havler, M. J. Humphrey
Publikováno v:
Xenobiotica. 18:519-532
1. [2'-14C]Idazoxan was rapidly and completely absorbed after its oral administration to rats. 2. After administration of either [2'-14C] or [6,7-3H]idazoxan, radioactivity was taken up by a wide range of tissues and became localized, especially in t
Publikováno v:
Journal of Chromatography A. 204:195-200
A novel high-performance ligand-exchange technique based upon complexation with Cu 2+ for the rapid and direct separation of l -pyroglutamyl- l -histidyl- l -3,3-dimethylprolineamide from its d - l - l , l - d - l and l - l - d isomers is described a
Publikováno v:
European Journal of Clinical Pharmacology. 19:119-125
A high pressure liquid chromatographic assay was developed for simultaneous measurement of the plasma levels of tolmesoxide and its principal metabolite, RX71112. The assay was used to study the disposition of intravenous and oral tolmesoxide in ten
Publikováno v:
Phytochemistry. 12:569-572
Biosynthesis of ecdysterone from [4- 14 C, 3- 3 H]cholesterol in Taxus baccata does not involve obligatory oxidation at C-3 during the formation of the A/B- cis ring junction.
Publikováno v:
European journal of clinical pharmacology. 29(6)
A high performance liquid chromatographic method was developed for the quantitative determination of idazoxan in plasma. The assay was used to study the disposition of the drug after intravenous infusion and oral administration to five normal subject
Autor:
J G, Lloyd-Jones
Publikováno v:
The Journal of international medical research. 5
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 5(4)
The plasma concentration of the anti-inflammatory drug fenclofenac was investigated in volunteers following single oral doses of 200, 500 and 600 mg, as well as multiple doses of 600mg b.i.d. over five days, using gas chromatography with electron cap
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 5(4)
Buprenorphine is a newly-developed strong analgesic. A selected ion monitoring method has been developed to measure its plasma levels over the concentration range 20-3000ng ml-1. Six baboons each received intravenous and intramuscular doses of bupren