Zobrazeno 1 - 10
of 117
pro vyhledávání: '"J. G. Jurcic"'
Autor:
D. A. Sallman, M. M. Al Malki, A. S. Asch, E. S. Wang, J. G. Jurcic, T. J. Bradley, I. W. Flinn, D. A. Pollyea, S. N. Kambhampati, T. N. Tanaka, J. F. Zeidner, G. Garcia-Manero, D. Jeyakumar, L. Gu, A. Tan, M. Chao, C. O’Hear, I. Lal, P. Vyas, N. Daver
Publikováno v:
HemaSphere, Vol 6, Pp 67-68 (2022)
Externí odkaz:
https://doaj.org/article/f11a8ee031f8479881eff9499ea7ccf4
Publikováno v:
Current topics in microbiology and immunology. 313
Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia (AML) for which a number of targeted therapies have been developed. The "targets" have included both genotypic and phenotypic features of the disease. The application of m
Autor:
J. G. Jurcic
Publikováno v:
Haematology and Blood Transfusion Hämatologie und Bluttransfusion ISBN: 9783642639494
In recent years, monoclonal antibodies have become an important cancer therapeutic modality. Genetically engineered humanized antibodies have demonstrated activity against both minimal residual disease and overt leukemia. High-dose radioimmunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20815376cc6519ea641a4efe4c31e717
https://doi.org/10.1007/978-3-642-59358-1_30
https://doi.org/10.1007/978-3-642-59358-1_30
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(1)
Kinetic analysis of gamma camera patient images can provide time-dependent information about antibody behavior. Current region-of-interest-based techniques for the kinetic analysis of these images rely on user selection and drawing of regions to be a
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)
Despite achieving complete remission with retinoic acid (RA), most patients with acute promyelocytic leukemia (APL) have minimal residual disease detectable by reverse transcription-PCR (RT-PCR) amplification. HuM195, a humanized monoclonal antibody
Autor:
G, Sgouros, A M, Ballangrud, J G, Jurcic, M R, McDevitt, J L, Humm, Y E, Erdi, B M, Mehta, R D, Finn, S M, Larson, D A, Scheinberg
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(11)
Data from nine patients with leukemia participating in a phase I activity-escalation study of HuM195, labeled with the alpha-particle emitter 213Bi (half-life = 45.6 min), were used to estimate pharmacokinetics and dosimetry. This is the first trial
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(10)
HuM195 is a recombinant humanized IgG1 monoclonal antibody reactive with CD33, a Mr 67,000 glycoprotein expressed on early myeloid progenitor cells and myeloid leukemia cells. HuM195 has been shown to rapidly target and saturate acute myeloid leukemi
Autor:
J G, Jurcic, D A, Scheinberg
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(12)
Autor:
J G, Jurcic, P C, Caron, T K, Nikula, E B, Papadopoulos, R D, Finn, O A, Gansow, W H, Miller, M W, Geerlings, R P, Warrell, S M, Larson
Publikováno v:
Cancer research. 55
M195, a mouse monoclonal antibody reactive with the early myeloid antigen CD33, has been shown to target leukemia cells in patients and to reduce large leukemic burdens when labeled with 131I. A complementarity-determining region-grafted, humanized v
Autor:
J G, Jurcic, P C, Caron, W H, Miller, T J, Yao, P, Maslak, R D, Finn, S M, Larson, R P, Warrell, D A, Scheinberg
Publikováno v:
Leukemia. 9(2)
Acute promyelocytic leukemia (APL) provides a model to examine the sequential use of selective oncogene product-targeted and lineage-targeted agents. All-trans retinoic acid (RA) has been shown to produce brief remissions by a novel differentiating m