Výsledky vyhledávání - "J. G. Gribben"

Akademický článek

Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

How the bone marrow microenvironment evolves during induction chemotherapy to facilitate acute lymphoblastic leukaemia (ALL) survival remains unclear. Here the authors show that adipocytes emergent during ALL therapy aid the survival of ALL cells thr

Externí odkaz: https://doaj.org/article/5bd437ead45f4de29da3fc82c6989399

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Induction of T cell clonal anergy results in resistance, whereas CD28-mediated costimulation primes for susceptibility to Fas- and Bax-mediated programmed cell death

Autor: V A Boussiotis, B J Lee, G J Freeman, J G Gribben, L M Nadler

Publikováno v: The Journal of Immunology. 159:3156-3167

Since TCR-mediated stimulation induces T cells to become sensitive to Fas-mediated activation-induced cell death (Fas-AICD), we examined whether anergized and CD28-costimulated T cell clones were equally sensitive to Fas-AICD. Here, we show that TCR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54ec4770e293ad9b4f39be856d3c466a
https://doi.org/10.4049/jimmunol.159.7.3156

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In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease

Autor: J M, Munro, A S, Freedman, J C, Aster, J G, Gribben, N C, Lee, K K, Rhynhart, J, Banchereau, L M, Nadler

Publikováno v: Blood. 83:793-798

The B-lymphocyte/accessory-cell activation antigen B7 (BB1) has been shown in vitro to stimulate T-lymphocyte proliferation and cytokine production via CD28 present on the latter cells. In this study, benign lymphoid tissues, lymphomas, and extralymp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5625734b039b712cc3f7051fec93ea8
https://doi.org/10.1182/blood.v83.3.793.bloodjournal833793

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In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease

Autor: Jon C. Aster, Arnold S. Freedman, Lee M. Nadler, K Rhynhart, JM Munro, N Lee, J Banchereau, J. G. Gribben

Publikováno v: Blood. 83:793-798

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc4e91d33211c8cba1d641c0b156357b
https://doi.org/10.1182/blood.v83.3.793.793

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Autologous and allogeneic bone marrow transplantation for poor prognosis patients with B-cell chronic lymphocytic leukemia

Autor: Robert J. Soiffer, Pearl Leavitt, Donna Neuberg, Geraldine S. Pinkus, J. G. Gribben, K Pesek, Heather Daley, Arnold S. Freedman, SN Rabinowe, John F. Daley

Publikováno v: Blood. 82:1366-1376

Twenty patients with poor prognosis B-cell chronic lymphocytic leukemia (B-CLL) underwent uniform high-dose chemoradiotherapy followed by rescue with multiple monoclonal antibody-purged autologous bone marrow (BM) (12 patients) or T-cell-depleted all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ea3fece5aa0a2e1f07cc0e9d3df97
https://doi.org/10.1182/blood.v82.4.1366.1366

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Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

Autor: Arnold S. Freedman, K Pesek, S D Woo, Claude D. Gimmi, Neil L. Spector, F Coral, Donna Neuberg, Laura Saporito, J. G. Gribben, Michael Barber

Publikováno v: Blood. 81:3449-3457

Although molecular biologic techniques can now detect minimal numbers of residual cancer cells in patients in complete clinical remission, the clinical significance of minimal residual disease has never been conclusively established. If the detection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fd928a8c89de8ee5b64f09210aa2608
https://doi.org/10.1182/blood.v81.12.3449.3449

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Adjuvant immunotoxin therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with B-cell non- Hodgkin's lymphoma

Autor: JA Taylor, C L Epstein, John M. Lambert, L Eliseo, Michael L. Grossbard, Walter A. Blattler, J Kinsella, Arnold S. Freedman, J. G. Gribben, SN Rabinowe

Publikováno v: Blood. 81:2263-2271

Anti-B-blocked ricin (anti-B4-bR) combines the specificity of the anti- B4 (CD19) monoclonal antibody with the protein toxin “blocked ricin.” In blocked ricin, affinity ligands are attached to the ricin B-chain to attenuate its lectin binding cap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45e4886b7bdc4995163e812e74f6fb83
https://doi.org/10.1182/blood.v81.9.2263.2263

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Bone marrows of non-Hodgkin's lymphoma patients with a bcl-2 translocation can be purged of polymerase chain reaction-detectable lymphoma cells using monoclonal antibodies and immunomagnetic bead depletion

Autor: J G, Gribben, L, Saporito, M, Barber, K W, Blake, R M, Edwards, J D, Griffin, A S, Freedman, L M, Nadler

Publikováno v: Blood. 80:1083-1089

Using the extremely sensitive technique of polymerase chain reaction (PCR) to detect the bcl-2 translocation, only 50% of bone marrows could be purged of PCR-detectable lymphoma cells using a cocktail of three anti-B-cell monoclonal antibodies (MoAbs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b800ffa5a5f25957b48984b708cfc6
https://doi.org/10.1182/blood.v80.4.1083.bloodjournal8041083

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