Pericytes Modulate Third-Generation Tyrosine Kinase Inhibitor Sensitivity in EGFR-Mutated Lung Cancer Cells Through IL32-β5-Integrin Paracrine Signaling.

Autor: Huang C; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Guangzhou Key Laboratory of Precise Diagnosis and Treatment of Biliary Tract Cancer, Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Huang X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Qiu X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Kong X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Wu C; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Jiang X; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Yao M; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Department of Respiratory Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Wang M; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Department of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China., Su L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Guangdong Provincial Key Laboratory of Urological Diseases, Guangzhou Medical University, Guangzhou, 510120, China., Lv C; Clinical Biobank Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China., Wong PP; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.; Guangzhou Key Laboratory of Precise Diagnosis and Treatment of Biliary Tract Cancer, Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Oct 22, pp. e2405130. Date of Electronic Publication: 2024 Oct 22.

Innovative Strategies for the Treatment of CLL

Autor: Lee M. Nadler, Bruce D. Cheson, J. G. Gribben, Michael J. Keating, B. Robertson

Publikováno v: Leukemia & Lymphoma. 22:53-64

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e09f1b53c6e520b49c487e8221732d2
https://doi.org/10.3109/10428199609102703

In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease

Autor: J M, Munro, A S, Freedman, J C, Aster, J G, Gribben, N C, Lee, K K, Rhynhart, J, Banchereau, L M, Nadler

Publikováno v: Blood. 83:793-798

The B-lymphocyte/accessory-cell activation antigen B7 (BB1) has been shown in vitro to stimulate T-lymphocyte proliferation and cytokine production via CD28 present on the latter cells. In this study, benign lymphoid tissues, lymphomas, and extralymp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5625734b039b712cc3f7051fec93ea8
https://doi.org/10.1182/blood.v83.3.793.bloodjournal833793

Early Diagnosis of Colorectal Cancer Based on Bisulfite‐free Site‐specific Methylation Identification PCR Strategy: High‐Sensitivity, Accuracy, and Primary Medical Accessibility.

Autor: Zhen, Linqing^1,2 (AUTHOR), Tang, Xinlu¹ (AUTHOR), Xu, Zhengguo³ (AUTHOR), Huang, Yizhou^1,2 (AUTHOR), Qian, Xiaohua^1,2 (AUTHOR), Lin, Haiping⁴ (AUTHOR), Li, Chao³ (AUTHOR), Cui, Rong⁵ (AUTHOR), Fang, Hongsheng⁶ (AUTHOR), Yang, Hao^1,2 (AUTHOR), Qiu, Jiani^1,2 (AUTHOR), Fang, Zhaoqi⁷ (AUTHOR), Peng, Xiaohuan^1,2 (AUTHOR), Jin, Yifeng⁵ (AUTHOR), Nie, Jianing⁷ (AUTHOR), Guo, Shiwei³ (AUTHOR), Wang, Yuguang³ (AUTHOR), Zhong, Ming⁴ (AUTHOR) drzhongming1966@163.com, Gu, Hongchen^1,2 (AUTHOR) hcgu@sjtu.edu.cn, Xu, Hong^1,2 (AUTHOR) xuhong@sjtu.edu.cn

Publikováno v: Advanced Science. 9/4/2024, Vol. 11 Issue 33, p1-16. 16p.

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

Autor: Arnold S. Freedman, K Pesek, S D Woo, Claude D. Gimmi, Neil L. Spector, F Coral, Donna Neuberg, Laura Saporito, J. G. Gribben, Michael Barber

Publikováno v: Blood. 81:3449-3457

Although molecular biologic techniques can now detect minimal numbers of residual cancer cells in patients in complete clinical remission, the clinical significance of minimal residual disease has never been conclusively established. If the detection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fd928a8c89de8ee5b64f09210aa2608
https://doi.org/10.1182/blood.v81.12.3449.3449