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Whole-genome sequencing of Klebsiella pneumoniae MDR circulating in a pediatric hospital setting: a comprehensive genome analysis of isolates from Guayaquil, Ecuador

Autor: I. Mejía-Limones, D. Andrade-Molina, G. Morey-León, J. C. Hidalgo-Olmedo, J. G. Chang-Asinc, J. C. Fernández-Cadena, M. Rojas

Publikováno v: BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)

Abstract Background Klebsiella pneumoniae is the major cause of nosocomial infections worldwide and is related to a worsening increase in Multidrug-Resistant Bacteria (MDR) and virulence genes that seriously affect immunosuppressed patients, long-sta

Externí odkaz: https://doaj.org/article/86fafb59437e4dc096bbf0b13a304d79

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The relationship between nicotinic receptors and cognitive functioning in healthy aging: An in vivo positron emission tomography (PET) study with 2-[18F]fluoro-A-85380

Autor: Christopher C. Rowe, Pradeep J. Nathan, Kathryn A. Ellis, J. G. Chan, Julia R. Ellis, J Bradley, Henri Tochon-Danguy, Graeme O'Keefe, Rachel S. Mulligan, Victor L. Villemagne, Gregory Raymond Savage

Publikováno v: Synapse. 63:752-763

Extensive experimental and neuropathological evidence supports the general hypothesis that decline in the basal forebrain cholinergic system contributes significantly to age-related cognitive impairment. Postmortem studies suggest reductions in neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978ca4dcec1b6eef5a1a64757a10d0dc
https://doi.org/10.1002/syn.20642

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The fate of hypoxic tissue on 18F-fluoromisonidazole positron emission tomography after ischemic stroke

Autor: S J, Read, T, Hirano, D F, Abbott, R, Markus, J I, Sachinidis, H J, Tochon-Danguy, J G, Chan, G F, Egan, A M, Scott, C F, Bladin, W J, McKay, G A, Donnan

Publikováno v: Annals of neurology. 48(2)

We studied 24 patients up to 51 hours after ischemic stroke using 18F-fluoromisonidazole positron emission tomography to determine the fate of hypoxic tissue likely to represent the ischemic penumbra. Areas of hypoxic tissue were detected on positron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df991624c0182932dfa156f8cb582a89
https://pubmed.ncbi.nlm.nih.gov/10939574

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Identifying hypoxic tissue after acute ischemic stroke using PET and 18F-fluoromisonidazole

Autor: Geoffrey A. Donnan, Andrew M. Scott, W J McKay, Stephen J. Read, Christopher F. Bladin, John I. Sachinidis, J. G. Chan, Gary F. Egan, David F. Abbott, T. Hirano, Henri Tochon-Danguy

Publikováno v: Neurology. 51(6)

Objective: To show that PET with 18 F-fluoromisonidazole ( 18 F-FMISO) can detect peri-infarct hypoxic tissue in patients after ischemic stroke. Background: PET with 15 O-labeled oxygen and water is the only established method for identifying the isc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a744da542775c1622198410caf08c4ca
https://pubmed.ncbi.nlm.nih.gov/9855512

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Ictal SPECT using technetium-99m-HMPAO: methods for rapid preparation and optimal deployment of tracer during spontaneous seizures

Autor: M R, Newton, M C, Austin, J G, Chan, W J, McKay, C C, Rowe, S F, Berkovic

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 34(4)

Ictal SPECT provides unique information for the clinician treating patients with refractory epilepsy and reveals insights into the pathophysiology of seizures. We describe our methods for the routine attainment of ictal images using 99mTc-HMPAO. We h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d96d506c083625c229b58640f29d9846
https://pubmed.ncbi.nlm.nih.gov/8455086

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