Zobrazeno 1 - 10
of 98
pro vyhledávání: '"J. G. Bekesi"'
Autor:
Donna Mildvan, Jian Dong Jiang, Henry S. Sacks, J. P. Roboz, Michael Schlesinger, J. G. Bekesi
Publikováno v:
Journal of Clinical Immunology. 17:185-192
Apoptosis mediated via the CD95 (FAS/APO-1) receptor is thought to play a role in the depletion of CD4+ T cells in HIV infection. In the present study expression of the CD95 antigen on lymphocyte subsets and the plasma level of soluble CD95 (sCD95) w
Autor:
Jian Dong Jiang, Michael Schlesinger, Julia P. Roboz, J. G. Bekesi, Allan L. Goldstein, M. Badamchian, Fo Nian Chu
Publikováno v:
Clinical Immunology and Immunopathology. 73:252-260
The aim of the present study was to investigate the biochemical structure and pathogenic significance of the soluble CD8 (sCD8) present in the serum of HIV-1-infected individuals. In a longitudinal study of a cohort of HIV-infected homosexuals and th
Publikováno v:
ChemInform. 27
Autor:
Paolo Alberto Paciucci, R. Odchimar, P. A. Chahinian, J. S. Ryder, J. G. Bekesi, James F. Holland
Publikováno v:
American Journal of Clinical Oncology. 14:341-348
Twelve women and 7 men, median age 58 (range 17-74), with a diagnosis of non-small-cell lung cancer (11 patients), inflammatory breast cancer (5 patients), osteosarcoma (2 patients), and colon carcinoma (1 patient) were studied. Treatment consisted o
Publikováno v:
Cancer research. 58(23)
3-(Iodoacetamido)-benzoylurea (3-IAABU) is a newly synthesized antitubulin compound with a molecular weight of 347. 3-IAABU exhibited anticancer activity in a variety of tumor cell lines with ID90 in the range of 0.015-0.29 microM for leukemic cells
Publikováno v:
Anti-cancer drug design. 13(7)
The four title compounds (not hitherto reported) were synthesized from 3-aminobenzoic acid through its trifluoroacetic acid-acid chloride derivative, reaction with urea and aminolytic deprotection to yield 3-aminobenzoylurea, followed by unconvention
Publikováno v:
Cancer research. 58(10)
We have synthesized a new compound, 3-bromoacetylamino benzoylurea (3-BAABU), which showed strong cancericidal activity by inducing irreversible mitotic arrest and subsequently apoptosis in human T cell leukemic cells (CEM), human biphenotypic leukem
Publikováno v:
Cancer research. 57(21)
ID50 and ID90 values for L-prolyl-L-m-[bis(chloroethyl)amino]-phenylalanyl-L-norvaline ethyl ester HCl (MF13), were determined in four murine (leukemia, lymphoma, melanoma, and lung) and eight human cancer cell lines (two leukemia, prostate, kidney,
Publikováno v:
Journal of clinical immunology. 17(2)
Apoptosis mediated via the CD95 (FAS/APO-1) receptor is thought to play a role in the depletion of CD4+ T cells in HIV infection. In the present study expression of the CD95 antigen on lymphocyte subsets and the plasma level of soluble CD95 (sCD95) w