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Expression of T17M rhodopsin (T17M) in rods activates the Unfolded Protein Response (UPR) and leads to the development of autosomal dominant retinitis pigmentosa (adRP). The rod death occurs in adRP retinas prior to cone photoreceptor death, so the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8539bd31bd2483e0f844e3f5e9f7071
https://europepmc.org/articles/PMC6056179/
https://europepmc.org/articles/PMC6056179/
Autor:
D. Bloch, Tim Coulson, K J Fullard, William Amos, J. Worthington Wilmer, John P. Croxall, Theresa M. Burg
The relationship between fitness and parental similarity has been dominated by studies of how inbreeding depression lowers fecundity in incestuous matings. A widespread implicit assumption is that adult fitness (reproduction) of individuals born to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf33327ff9a254e2733fa17894599b9
https://doi.org/10.1098/rspb.2001.1751
https://doi.org/10.1098/rspb.2001.1751
Autor:
Roderick J. Fullard, Leo G. Carney
Publikováno v:
Acta Ophthalmologica. 64:216-220
A non-invasive biochemical method for assessing the effects of contact lens wear on the in vivo corneal epithelium is described. A fluorometric technique is used to measure the activities of lactate dehydrogenase (LDH) and malate dehydrogenase (MDH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae5192756a3a28daa734107407ef0d5
https://doi.org/10.1111/j.1755-3768.1986.tb06903.x
https://doi.org/10.1111/j.1755-3768.1986.tb06903.x
Publikováno v:
Current Eye Research. 33:525-544
To compare instruments and reagents used for cytometric bead-based assay (CBA) of cytokines in human tears.Two CBA instruments and reagent kits from five vendors were compared in parallel. Vendor protocols were modified to accommodate tear volumes. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b0361ec144bc6b012194097cec3998
https://doi.org/10.1080/02713680802190085
https://doi.org/10.1080/02713680802190085
Autor:
Roderick J. Fullard, Oleg S. Gorbatyuk, Marina S. Gorbatyuk, Austin R. Lenox, Yogesh Bhootada
Publikováno v:
Neuroscience letters. 609
An unfolded protein response (UPR) in addition to oxidative stress and the inflammatory response is known to be activated in age-related ocular disorders, such as macular degeneration, diabetic retinopathy, glaucoma, and cataracts. Therefore, we aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6dab9db9bf6706cb9d02e387bca63f
https://pubmed.ncbi.nlm.nih.gov/26467812
https://pubmed.ncbi.nlm.nih.gov/26467812
Publikováno v:
Optometry and Vision Science. 83:836-842
Purpose. The purpose of this study was to compare the new, computerized Aniseikonia Inspector with the Space Eikonometer for the measurement of aniseikonia. Methods. Eighteen subjects, ages 21 to 61 years, with normal binocular vision and normal visu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacf5be10b173e810873b1b66fc89cd5
https://doi.org/10.1097/01.opx.0000238722.34167.cc
https://doi.org/10.1097/01.opx.0000238722.34167.cc
Publikováno v:
Optometry and vision science : official publication of the American Academy of Optometry. 92(2)
This study measured aniseikonia before and after the first and second cataract surgeries in ametropic adults. The relationship of aniseikonia to anisometropia and its effect on stereopsis, ocular alignment, and clinical symptoms were determined.Seven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81454b48ab2e5584a403da9d0325816
https://pubmed.ncbi.nlm.nih.gov/25546829
https://pubmed.ncbi.nlm.nih.gov/25546829
Publikováno v:
Current eye research. 39(1)
This study investigates the extent of the human transcriptome that can be quantified from conjunctival impression cytology extracts. The aim is to determine if sufficient RNA can be isolated from a patient's conjunctival surface to identify differenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38817081f328c1399fa60e899c8e0ddc
https://pubmed.ncbi.nlm.nih.gov/24047118
https://pubmed.ncbi.nlm.nih.gov/24047118
Autor:
Roderick J. Fullard, John E. Bradley, Larezia Williams, L. E. Kehinde, Nicole Guyette, Clara Edwards, Mark Beasley, My-Tho K. Tran, Tammy Than
Purpose Low tear volume limits the use of nonstimulated (NS) microcapillary tear collection in aqueous-deficient (AD) patients. Adding a small amount of "washout" fluid to the eye prior to tear collection is a potentially viable alternative method fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf9281e6ffe7f8834ee96663b31031a
https://europepmc.org/articles/PMC3668804/
https://europepmc.org/articles/PMC3668804/