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The MicroArray Quality Control (MAQC)-IIII study of common practices for the development and validation of microarray-based predictive models

Autor: L. SHI, G. CAMPBELL, W. JONES, F. CAMPAGNE, Z. WEN, S. WALKER, Z. SU, T. CHU, F. GOODSAID, L. PUSZTAI, J. SHAUGHNESSY, A. OBERTHUER, R. THOMAS, R. PAULES, M. FIELDEN, B. BARLOGIE, W. CHEN, P. DU, M. FISCHER, C. FURLANELLO, B. GALLAS, X. GE, D. MEGHERBI, W. SYMMANS, M. WANG, J. ZHANG, H. BITTER, B. BRORS, P. BUSHEL, M. BYLESJO, M. CHEN, J. CHENG, J. CHOU, T. DAVISON, M. DELORENZI, Y. DENG, V. DEVANARAYAN, D. DIX, J. DOPAZO, K. DORFF, F. ELLOUMI, J. FAN, S. FAN, X. FAN, H. FANG, N. GONZALUDO, K. HESS, H. HONG, J. HUAN, R. IRIZARRY, R. JUDSON, D. JURAEVA, S. LABABIDI, C. LAMBERT, L. LI, Y. LI, Z. LI, S. LIN, G. LIU, E. LOBENHOFER, J. LUO, W. LUO, M. MCCALL, Y. NIKOLSKY, G. PENNELLO, R. PERKINS, R. PHILIP, V. POPOVICI, N. PRICE, F. QIAN, A. SCHERER, T. SHI, W. SHI, J. SUNG, D. THIERRY-MIEG, J. THIERRY-MIEG, V. THODIMA, J. TRYGG, L. VISHNUVAJJALA, S. WANG, J. WU, Y. WU, Q. XIE, W. YOUSEF, L. ZHANG, X. ZHANG, S. ZHONG, Y. ZHOU, S. ZHU, D. ARASAPPAN, W. BAO, A. LUCAS, F. BERTHOLD, R. BRENNAN, A. BUNESS, J. CATALANO, C. CHANG, R. CHEN, Y. CHENG, J. CUI, W. CZIKA, F. DEMICHELIS, X. DENG, D. DOSYMBEKOV, R. EILS, Y. FENG, J. FOSTEL, S. FULMER-SMENTEK, J. FUSCOE, L. GATTO, W. GE, D. GOLDSTEIN, L. GUO, D. HALBERT, J. HAN, S. HARRIS, C. HATZIS, D. HERMAN, J. HUANG, R. JENSEN, R. JIANG, C. JOHNSON, G. JURMAN, Y. KAHLERT, S. KHUDER, M. KOHL, J. LI, M. LI, Q. LI, S. LI, J. LIU, Y. LIU, Z. LIU, L. MENG, M. MADERA, F. MARTINEZ-MURILLO, I. MEDINA, J. MEEHAN, K. MICLAUS, R. MOFFITT, D. MONTANER, P. MUKHERJEE, G. MULLIGAN, P. NEVILLE, T. NIKOLSKAYA, B. NING, G. PAGE, J. PARKER, R. PARRY, X. PENG, R. PETERSON, J. PHAN, B. QUANZ, Y. REN, S. RICCADONNA, A. ROTER, F. SAMUELSON, M. SCHUMACHER, J. SHAMBAUGH, Q. SHI, R. SHIPPY, S. SI, A. SMALTER, C. SOTIRIOU, M. SOUKUP, F. STAEDTLER, G. STEINER, T. STOKES, Q. SUN, P. TAN, R. TANG, Z. TEZAK, B. THORN, M. TSYGANOVA, Y. TURPAZ, S. VEGA, R. VISINTAINER, J. VON FRESE, C. WANG, E. WANG, J. WANG, W. WANG, F. WESTERMANN, J. WILLEY, M. WOODS, S. WU, N. XIAO, J. XU, L. XU, L. YANG, X. ZENG, M. ZHANG, C. ZHAO, R. PURI, U. SCHERF, W. TONG, R. WOLFINGER, MAQC Consortium

Publikováno v: NATURE BIOTECHNOLOGY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
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r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)

Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36 independent teams analyzed six microarray data sets t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0eb81fd072db5db81e074b5d3c89b532
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2694

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Assessment of the genotoxic effects of methyl chloride in human lymphoblasts

Autor: Andrew D. Kligerman, T.R. Skopek, Paula F. Allen, J.L. Wilmer, E. Bermudez, J. Fostel

Publikováno v: Mutation research. 155(1-2)

The activity of methyl chloride was measured in 4 genotoxicity assays. In an established human lymphoblast line, a 3-h treatment with 0-5% methyl chloride resulted in a dose-related increase in mutant fraction at the thymidine kinase locus and induct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9caa7b5150a1d842a1dc02c63722d4
https://pubmed.ncbi.nlm.nih.gov/3881666