Zobrazeno 1 - 10 of 84 pro vyhledávání: '"J. Folmer"'
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Akademický článek
Die toksikologiese telefoniese konsultasies gerig aan die Departement Farmakologie van die Universiteit van die Vrystaat gedurende 1998
Autor: C.J. Engelbrecht, J. Folmer, W.C. Steyn, G. Joubert, N. Fourie
Publikováno v: South African Family Practice, Vol 25, Iss 5 (2002)
Background: Epidemiologic surveys of poisonings as well as inquiries regarding poisonings are necessary to obtain information for the combating as well successful medical management of poisonings. Methods: All telephonic consultations regarding pois
Externí odkaz: https://doaj.org/article/3f626f5308554b49b8d68c73660935d6
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Elucidation of a Novel Bioactivation Pathway of a 3,4-Unsubstituted Isoxazole in Human Liver Microsomes: Formation of a Glutathione Adduct of a Cyanoacrolein Derivative after Isoxazole Ring Opening
Autor: James B. Campbell, Doug Burdette, Jian Yu, James J. Folmer, James Doherty, Valerie Hoesch
Publikováno v: Drug Metabolism and Disposition. 39:302-311
Studies on the biotransformation of isoxazole rings have shown that molecules containing a C3-substituted isoxazole or a 1,2-benzisoxazole can undergo a two-electron reductive ring cleavage to form an imine. In the absence of a C3 substituent, the is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ae31cc3f497b0fbdd8799a22873c9b
https://doi.org/10.1124/dmd.110.036285
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4
Total Syntheses of the Securinega Alkaloids (+)-14,15-Dihydronorsecurinine, (−)-Norsecurinine, and Phyllanthine
Autor: Steven M. Weinreb, Kim M. Werner, James J. Folmer, Matthew G. LaPorte, Gyoonhee Han
Publikováno v: The Journal of Organic Chemistry. 65:6293-6306
A new strategy for enantiospecific construction of the Securinega alkaloids has been developed and applied in total syntheses of (+)-14,15-dihydronorsecurinine (8), (-)-norsecurinine (6), and phyllanthine (2). The B-ring and C7 absolute stereochemist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d05e3b56bf114ca1169301ecaa21774
https://doi.org/10.1021/jo000260z
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5
A New Enantioselective Approach to Total Synthesis of the Securinega Alkaloids: Application to (−)-Norsecurinine and Phyllanthine
Autor: Steven M. Weinreb, James J. Folmer, Matthew G. LaPorte, Kim M. Werner, Gyoonhee Han
Publikováno v: Angewandte Chemie International Edition. 39:237-240
An inexpensive proline derivative and chiral control feature in the total synthesis of securinega alkaloids (-)-norsecurinine (1) and phyllanthine (2). Key steps in the synthesis of 1 include an intramolecular ketonitrile coupling and application of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a773ff1e5503a3e34886c7b1859cf7c
https://doi.org/10.1002/(sici)1521-3773(20000103)39:1<237::aid-anie237>3.0.co
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6
Synthesis of Carbacephems from Serine
Autor: Dung L. Thai, Henry Rapoport, James J. Folmer, Carles Acero
Publikováno v: The Journal of Organic Chemistry. 63:8170-8182
Carbacephems have been synthesized from d-serine by two routes involving construction first of the six-membered ring followed by cyclization to give the bicyclic β-lactam. In one route, alkylation of a lactim ether was accomplished with Ni(Acac)2 as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f91fbc3bdae32a51644f5d0e77dc12dd
https://doi.org/10.1021/jo980592s
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7
Generation of esters from carboxylic acids using Appel's salt (4,5-dichloro-1,2,3-dithiazolium chloride)
Autor: Steven M. Weinreb, James J. Folmer
Publikováno v: Tetrahedron Letters. 34:2737-2740
Esters can be generated directly in good yields under mild conditions from the corresponding carboxylic acid and alcohol using Appel's salt (4,5-dichloro-1,2,3-dithiazolium chloride) and 2,6-lutidine.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8872b42c1d0823c87c0339b8c94e44a
https://doi.org/10.1016/s0040-4039(00)73549-0
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8
ChemInform Abstract: Generation of Esters from Carboxylic Acids Using Appel′s Salt (4,5- Dichloro-1,2,3-dithiazolium Chloride)
Autor: James J. Folmer, Steven M. Weinreb
Publikováno v: ChemInform. 24
Esters can be generated directly in good yields under mild conditions from the corresponding carboxylic acid and alcohol using Appel's salt (4,5-dichloro-1,2,3-dithiazolium chloride) and 2,6-lutidine.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c58cbcca0422aefc449073f15b6814f
https://doi.org/10.1002/chin.199339137
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10
Effects of microgravity or simulated launch on testicular function in rats
Autor: R. P. Amann, D. R. Deaver, B. R. Zirkin, G. S. Grills, W. J. Sapp, D. N. Veeramachaneni, J. W. Clemens, S. D. Banerjee, J. Folmer, C. M. Gruppi, al. et
Publikováno v: Journal of Applied Physiology. 73:S174-S185
Testes from flight rats on COSMOS 2044 and simulated-launch, vivarium, or caudal-elevation control rats (5/group) were analyzed by subjective and quantitative methods. On the basis of observations of fixed tissue, it was evident that some rats had te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3322c00355e91d77303aac9e3f21711b
https://doi.org/10.1152/jappl.1992.73.2.s174
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