Zobrazeno 1 - 10
of 301
pro vyhledávání: '"J. Fleetwood"'
Autor:
Tanya J. Lupancu, Kevin M.C. Lee, Mahtab Eivazitork, Cecil Hor, Andrew J. Fleetwood, Andrew D. Cook, Moshe Olshansky, Stephen J. Turner, Richard de Steiger, Keith Lim, John A. Hamilton, Adrian A. Achuthan
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108079- (2023)
Summary: Glucocorticoids (GCs) are potent anti-inflammatory agents and are broadly used in treating rheumatoid arthritis (RA) patients, albeit with adverse side effects associated with long-term usage. The negative consequences of GC therapy provide
Externí odkaz:
https://doaj.org/article/5677e94626014801a13fe86a32d5bf63
Autor:
Kevin M.-C. Lee, Zihao Zhang, Adrian Achuthan, Andrew J. Fleetwood, Julia E. Smith, John A. Hamilton, Andrew D. Cook
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Background The cytokine, interleukin-23 (IL-23), can be critical for the progression of inflammatory diseases, including arthritis, and is often associated with T lymphocyte biology. We previously showed that certain lymphocyte-independent,
Externí odkaz:
https://doaj.org/article/b65df65eecae4eba8f05e807f9807c7a
Publikováno v:
Journal of Fungi, Vol 9, Iss 2, p 190 (2023)
Epichloë species form bioprotective endophytic symbioses with many cool-season grasses, including agriculturally important forage grasses. Despite its importance, relatively little is known about the molecular details of the interaction and the regu
Externí odkaz:
https://doaj.org/article/b06c81278fd542649b6ab48e20e82fbc
Autor:
Ming-Chin Lee, Reem Saleh, Adrian Achuthan, Andrew J. Fleetwood, Irmgard Förster, John A. Hamilton, Andrew D. Cook
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background Granulocyte macrophage-colony stimulating factor (GM-CSF) has been implicated in the pathogenesis of a number of inflammatory diseases and in osteoarthritis (OA). We identified previously a new GM-CSF→Jmjd3→interferon regulato
Externí odkaz:
https://doaj.org/article/7aa7862ad9284ab7bb2895fbe551b81a
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Macrophages are the first immune cells in the developing embryo and have a central role in organ development, homeostasis, immunity and repair. Over the last century, our understanding of these cells has evolved from being thought of as simp
Externí odkaz:
https://doaj.org/article/74f9aa12b7d44458a681fac9c613a3e2
Autor:
Man K. S. Lee, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, Andrew J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Externí odkaz:
https://doaj.org/article/877fdbb79e87480fa17aaf1845695887
Epichloë species form bioprotective endophytic symbioses with many cool-season grasses, including agriculturally important forage grasses. Despite its importance, relatively little is known about the molecular details of the interaction and the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7396246a4895c05403e85843fc146c5e
https://doi.org/10.20944/preprints202211.0521.v1
https://doi.org/10.20944/preprints202211.0521.v1
Autor:
Andrew J. Fleetwood, Man K.S. Lee, William Singleton, Adrian Achuthan, Ming-Chin Lee, Neil M. O'Brien-Simpson, Andrew D. Cook, Andrew J. Murphy, Stuart G. Dashper, Eric C. Reynolds, John A. Hamilton
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Porphyromonas gingivalis is one of the bacterial species most closely associated with periodontitis and can shed large numbers of outer membrane vesicles (OMVs), which are increasingly thought to play a significant role in bacterial virulence and pat
Externí odkaz:
https://doaj.org/article/facd0ad2ceeb44f3a8393eeeead9610a
Publikováno v:
Microorganisms, Vol 8, Iss 1, p 33 (2019)
VelA (or VeA) is a key global regulator in fungal secondary metabolism and development which we previously showed is required during the symbiotic interaction of Epichloë festucae with perennial ryegrass. In this study, comparative transcriptomic an
Externí odkaz:
https://doaj.org/article/a77e6064418248f8822d37d878216318
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