Zobrazeno 1 - 10
of 99
pro vyhledávání: '"J. Fernando Bazan"'
Autor:
Derrick C. Wan, Stefanie L. Morgan, Andrew L. Spencley, Natasha Mariano, Erin Y. Chang, Gautam Shankar, Yunhai Luo, Ted H. Li, Dana Huh, Star K. Huynh, Jasmine M. Garcia, Cole M. Dovey, Jennifer Lumb, Ling Liu, Katharine V. Brown, Abel Bermudez, Richard Luong, Hong Zeng, Victoria L. Mascetti, Sharon J. Pitteri, Jordon Wang, Hua Tu, Marco Quarta, Vittorio Sebastiano, Roel Nusse, Thomas A. Rando, Jan E. Carette, J. Fernando Bazan, Kevin C. Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Royal jelly is the queen-maker for the honey bee that also has effects on longevity, fertility, and regeneration in mammals. Here the authors provide evidence that its major protein component Royalactin, and the mammalian structural analog Regina, ma
Externí odkaz:
https://doaj.org/article/6ac458ba736146368698999f73b60666
Autor:
Ravi K. Nookala, Lars Langemeyer, Angela Pacitto, Bernardo Ochoa-Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazan, Tom L. Blundell
Publikováno v:
Open Biology, Vol 2, Iss 8 (2012)
Mutations in the renal tumour suppressor protein, folliculin, lead to proliferative skin lesions, lung complications and renal cell carcinoma. Folliculin has been reported to interact with AMP-activated kinase, a key component of the mammalian target
Externí odkaz:
https://doaj.org/article/971429b17e0d4c35b68de92b3d25f9d4
Autor:
Alexandra Tsirigotaki, Ann Dansercoer, Koen H.G. Verschueren, Iva Marković, Christoph Pollmann, Maximillian Hafer, Jan Felix, Catherine Birck, Wouter Van Putte, Dominiek Catteeuw, Jan Tavernier, J. Fernando Bazan, Jacob Piehler, Savvas N. Savvides, Kenneth Verstraete
Publikováno v:
Nature Structural & Molecular Biology. 30:551-563
The adipokine Leptin activates its type I cytokine receptor (LEP-R) in the hypothalamus to regulate body weight and exerts additional pleiotropic functions in immunity, fertility, and cancer. However, the structure and mechanism of Leptin-mediated LE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3315c5a9b86da7b75aec3cf441b412e
https://doi.org/10.1038/s41594-023-00941-9
https://doi.org/10.1038/s41594-023-00941-9
Publikováno v:
Nature Chemical Biology. 19:378-388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::580a61b3311bccfd10268a13cf320df2
https://doi.org/10.1038/s41589-022-01253-7
https://doi.org/10.1038/s41589-022-01253-7
Autor:
Zemin Zhang, Somasekar Seshagiri, J. Fernando Bazan, William F. Forrest, Jeremy Stinson, Dragan Sebisanovic, Brock Peters, Peter M. Haverty, Allison Waugh, Yan Zhang, Joshua S. Kaminker
Supplementary Figures 1-2 from Distinguishing Cancer-Associated Missense Mutations from Common Polymorphisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1083d38af384c9fb394fe6595c63fdee
https://doi.org/10.1158/0008-5472.22367006.v1
https://doi.org/10.1158/0008-5472.22367006.v1
Autor:
Zemin Zhang, Somasekar Seshagiri, J. Fernando Bazan, William F. Forrest, Jeremy Stinson, Dragan Sebisanovic, Brock Peters, Peter M. Haverty, Allison Waugh, Yan Zhang, Joshua S. Kaminker
Missense variants are commonly identified in genomic sequence but only a small fraction directly contribute to oncogenesis. The ability to distinguish those missense changes that contribute to cancer progression from those that do not is a difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6925da3fa1a0e366f51024c6c84ab6dd
https://doi.org/10.1158/0008-5472.c.6495380.v1
https://doi.org/10.1158/0008-5472.c.6495380.v1
Autor:
Zemin Zhang, Somasekar Seshagiri, J. Fernando Bazan, William F. Forrest, Jeremy Stinson, Dragan Sebisanovic, Brock Peters, Peter M. Haverty, Allison Waugh, Yan Zhang, Joshua S. Kaminker
Supplementary Methods from Distinguishing Cancer-Associated Missense Mutations from Common Polymorphisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e422c94542681196d873d18f71a2933
https://doi.org/10.1158/0008-5472.22367003.v1
https://doi.org/10.1158/0008-5472.22367003.v1
Ferroptosis is an iron-dependent form of cell death driven by the oxidation of polyunsaturated (PUFA) phospholipids. Large-scale genetic screens have pointed to a specialized role for PUFA ether phospholipids (ePLs) in promoting ferroptosis. Our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ce67dcd32bb1ebb34e0c4640d235445
https://doi.org/10.1101/2022.07.06.498872
https://doi.org/10.1101/2022.07.06.498872
Autor:
Katarzyna Skladanowska, Yehudi Bloch, Jamie Strand, Kerry White, Daniel Aldridge, Martin Welin, Derek Logan, Arne Soete, Romain Merceron, Casey Murphy, Mathias Provost, J. Fernando Bazan, Christopher Hunter, Jonathan Hill, Savvas N. Savvides
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::157f976d8d849b44a9a1b41c0d3d2339
https://doi.org/10.2139/ssrn.4120771
https://doi.org/10.2139/ssrn.4120771
Autor:
Junko Mukohyama, Ikuko Omori, Steven De Munck, Jan Felix, Savvas N. Savvides, Yehudi Bloch, Michiko Kurikawa, J. Fernando Bazan, Akihide Yoshimi, Omar Abdel-Wahab, Mathias Provost
Publikováno v:
Nature
NATURE
NATURE
Anaplastic lymphoma kinase (ALK)(1) and the related leukocyte tyrosine kinase (LTK)(2) are recently deorphanized receptor tyrosine kinases(3). Together with their activating cytokines, ALKAL1 and ALKAL2(4-6) (also called FAM150A and FAM150B or AUG be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a91a008c09db27ef01135232848a61b
https://pubmed.ncbi.nlm.nih.gov/34646012
https://pubmed.ncbi.nlm.nih.gov/34646012