Zobrazeno 1 - 10
of 84
pro vyhledávání: '"J. Fernández-Calvo"'
Autor:
M. E. Sarasquete, M C Chillón, R. López, Magdalena Sierra, J M Hernández, Marcos González, Adriana Armellini, A. Orfao, Miguel Alcoceba, J F San Miguel, Ramón García-Sanz, Marta Megido, M. Fuertes, Ana Balanzategui, J. Fernández-Calvo, Norma C. Gutiérrez
Publikováno v:
British Journal of Haematology. 141:212-215
RAN, ZHX2 and RCBTB2 (CHC1L) expression was evaluated by quantitative real time reverse transcription polymerase chain reaction in plasma cells from 85 monoclonal gammopathies: 58 symptomatic multiple myeloma (MM) (52 untreated, six relapsed), eight
Autor:
Miguel A. Sanz, Juan Ortega, Evarist Feliu, Eloy del Potro, Jesús M. Hernández-Rivas, Concepción Rivas, Eugenia Abella, Javier Bueno, Andrés Novo, Carlos Grande, Albert Oriol, Mar Tormo, Josep M. Ribera, M. Orts, J. Fernández-Calvo, Blanca Xicoy
Publikováno v:
Medicina Clínica. 126:41-46
Fundamento y objetivo La leucemia aguda linfoblastica (LAL) de fenotipo T incluye 4 subtipos inmunologicos: pro-T, pre-T, timica o cortical y madura. En algunos estudios, los subtipos LAL pro-T y maduro tienen un peor pronostico. El objetivo de este
Autor:
M. Fontanillas, José García-Laraña, Alfons Soler, Manel Callís, J. Fernández-Calvo, Jesús F. San Miguel, M. Jesús Moro, Laura Rosiñol, Ana Sureda, M. Victoria Mateos, Joan Bladé, Pilar Giraldo, Santiago Gardella, Luis Palomera, Felix Carbonell, Joaquín Díaz-Mediavilla, Josep M. Ribera, Josep Martí, Programa para el Estudio de la Terapéutica en Hemopatía Maligna, Abelardo Bárez, Llorenç Font, Jesús Trujillo
Publikováno v:
Blood. 106:3755-3759
The aim of the present randomized trial was to compare high-dose therapy (HDT) with continued conventional chemotherapy in patients with multiple myeloma (MM) who responded to the initial treatment. From May 1994 to October 1999, 216 patients (122 me
Autor:
J. Trujillo, E. Golvano, G. Mateo, Felix Carbonell, J. Bladé, J F San Miguel, Santiago Gardella, J. A. Soler, Ramón García-Sanz, J M Hernández, J. Fernández-Calvo
Publikováno v:
British Journal of Haematology. 127:159-164
SummaryMelphalan–prednisone (MP) has been the gold standard treatment for morethan 30 years in elderly multiple myeloma (MM) patients. In order to assesswhether the combination of dexamethasone with melphalan (MD) couldimprove on the efficacy of M
Autor:
Josefina Galende, J F San Miguel, J. Fernández-Calvo, J. A. Portero, Maria Isabel González-Fraile, Ramón García-Sanz, Gema Mateo, M C López-Berges, J M Hernández, Francisco Ortega, Abelardo Bárez, N. de las Heras, A. Orfao
Publikováno v:
International Journal of Cancer. 112:884-889
Although multiple myeloma (MM) is predominantly a disease of the elderly, few studies have focused on the identification of prognostic factors in this group of patients. Four hundred twenty five MM patients >65 years were uniformly treated with chemo
Autor:
Ana Balanzategui, Fernando Ramos, M C Chillón, J. Fernández-Calvo, M. González, Carina Fernández, Miguel Jf, Ramón García-Sanz
Publikováno v:
The Hematology Journal. 5:239-246
FLT3: gene alterations (internal tandem duplications - ITDs - and D835 mutations) are thought to be associated with poor-risk acute myeloid leukemia (AML). However, not all studies confirm this association, so it is still a matter of debate. Moreover
Autor:
M C López-Berges, M A García-Marcos, Marcos González, Alberto Orfao, Julia Almeida, Guillermo Martín-Núñez, M. Barbón, David Gonzalez, Ana Balanzategui, J. Fernández-Calvo, Teresa Vallespi, Jesus-Maria Hernandez, Alejandro Martín, Jesús F. San Miguel, Maria-Luz Sanchez, Josep F. Nomdedeu, Pilar de la Fuente
Publikováno v:
Blood. 102:2994-3002
Leukemic B-chronic lymphoproliferative disorders (B-CLPDs) are generally believed to derive from a monoclonal B cell; biclonality has only occasionally been reported. In this study, we have explored the incidence of B-CLPD cases with 2 or more B-cell
Autor:
Marcos González, José L. Hernández, Maria Jesus Moro, Alberto Orfao, Maria V. Mateos, Maria Dolores Caballero, Julia Almeida, Ramón García-Sanz, Marta Megido, Ricardo López-Pérez, Abelardo Bárez, Enrique M. Ocio, Jesús F. San Miguel, J. Fernández-Calvo
Publikováno v:
British Journal of Haematology. 118:1034-1040
Summary. In order to gain further insights into the role of the p16 gene in cell cycle regulation and the prognostic implications of its inactivation, we investigated the methylation status of the p16 gene in 98 untreated patients using a polymerase
Autor:
Marcos González, J. Fernández-Calvo, Joan Bladé, Ramón García-Sanz, Gema Mateo, Alberto Orfao, Begoña Suquía, José L. Hernández, Alejandro Martín, Jesús F. San Miguel
Publikováno v:
British Journal of Haematology. 118:239-242
Summary. Twelve patients with smouldering or indolent multiple myeloma (MM) received 12 courses of intravenous pamidronate as a single agent to evaluate both the antitumour and bone metabolism effects. One patient achieved minor response, eight had s
Autor:
Joan Bladé, Luis Palomera, Julia Almeida, C. López-Berges, José L. Hernández, Maria Jesus Moro, Dolores Caballero, Joaquín Díaz-Mediavilla, Alberto Orfao, J. Fernández-Calvo, Jesús F. San Miguel, Gema Mateo
Publikováno v:
Blood. 99:1853-1856
Multiparametric immunophenotyping can be a sensitive method for analyzing the plasma cell (PC) compartment in patients with multiple myeloma because it discriminates between myelomatous and normal PCs. Using this approach, we compared the efficacy of