Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J. Fauss"'
Publikováno v:
Gefahrstoffe. 80:217-224
Das Rauchen von Wasserpfeifen (Shishas) wird immer beliebter. Doch besonders in der Winterzeit steigt auch die Anzahl von Kohlenmonoxidvergiftungen (CO-Vergiftungen) in Shisha-Bars. Vergiftungsursache ist vor allem die zu große Anzahl gleichzeitig g
Publikováno v:
The MAK-Collection for Occupational Health and Safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cf3fa5aacac35142ce083eee1b7c5c8
https://doi.org/10.1002/3527600418.am10721e1918
https://doi.org/10.1002/3527600418.am10721e1918
Publikováno v:
The MAK-Collection for Occupational Health and Safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9133153bc532945c3e539f362fa3465b
https://doi.org/10.1002/3527600418.am10721d0019
https://doi.org/10.1002/3527600418.am10721d0019
Publikováno v:
The MAK-Collection for Occupational Health and Safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff14399968de3d4e334f5e71b6c52ab
https://doi.org/10.1002/3527600418.am156902d0019
https://doi.org/10.1002/3527600418.am156902d0019
Autor:
John P. Anderson, Dean R. Artis, Hing L. Sham, Roy K. Hom, Michael S. Dappen, Andrei W. Konradi, Simeon Bowers, Hu Pan, Robert A. Galemmo, Marc Adler, Pearl Tanaka, May Lin, Jeanne Baker, Lany Ruslim, Donald J. Fauss, Zhao Ren, Yong L. Zhu, Anh P. Truong, Danny Tam, Marcelle Bergeron, Lee H. Latimer, Paul Beroza, Jacek Jagodzinski, Heather Zhang, Michael P. Bova, George Tonn, Linnea Diep, Ruth Motter, Kent Fitzgerald, Nanhua Yao, Wayman Chan, Jennifer K. Hoffman, R. Jeffrey Neitz, Danielle L. Aubele
Publikováno v:
ChemMedChem. 8:1295-1313
Polo-like kinase-2 (Plk-2) has been implicated as the dominant kinase involved in the phosphorylation of α-synuclein in Lewy bodies, which are one of the hallmarks of Parkinson's disease neuropathology. Potent, selective, brain-penetrant inhibitors
Autor:
Kevin Tanaka, Marcelle Bergeron, Donald J. Fauss, Maria Armanda Viana Rodrigues, Jeanne Baker, Yangli Yang, Pui Seto, Monica You, Linnea Diep, Ruth Motter, Lilibeth Dofiles
Publikováno v:
Journal of Neuroscience Methods. 215:245-257
Tyrosine hydroxylase (TH) catalyses the rate-limiting step in the biosynthesis of catecholamines. TH expression is regulated in a tissue-specific manner during neuronal development and differentiation. Because of its key regulatory role in central an
Publikováno v:
Journal of Biological Chemistry. 276:37093-37101
V(D)J recombination is instigated by the recombination-activating proteins RAG1 and RAG2, which catalyze site-specific DNA cleavage at the border of the recombination signal sequence (RSS). Although both proteins are required for activity, core RAG1
Publikováno v:
Eye. 14:503-514
Glucocorticoid (GC) treatment of human trabecular meshwork (HTM) cells produces delayed, progressive cellular and extracellular protein/glycoprotein inductions with characteristics matching those for intraocular pressure elevation with corticosteroid
Autor:
Pu Chen, Donald J. Fauss, Ernest Bloom, Jon R. Polansky, Ron M. Kurtz, Elke Lütjen-Drecoll, Thai Nguyen, Hua Chen, Zhi-Dong Ma, Douglas H. Johnson
Publikováno v:
Ophthalmologica. 211:126-139
Studies of the effects of glucocorticoid (GC) and oxidative stress stimuli in differentiated cultures of human trabecular meshwork (HTM) cells have provided the rationale for our studies of a major new gene termed TIGR (trabecular meshwork inducible
Autor:
Paul Beroza, Michael P. Bova, Jennifer K. Hoffman, Jennifer Sealy, Heather Zhang, Marcelle Bergeron, Linnea Diep, Danny Tam, Ruth Motter, Zhao Ren, R. Jeffrey Neitz, Danielle L. Aubele, Kent Fitzgerald, Michael Ye, Wayman Chan, Pearl Tanaka, Deepal Pandya, Donald J. Fauss, Andrei W. Konradi, John P. Anderson, Roy K. Hom, Dean R. Artis, Hing L. Sham, Robert A. Galemmo, George Tonn, Jeanne Baker, Lany Ruslim, Yong L. Zhu, Anh P. Truong, Michael S. Dappen, Simeon Bowers
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(9)
Polo-like kinase-2 (Plk-2) is a potential therapeutic target for Parkinson’s disease and this Letter describes the SAR of a series of dihydropteridinone based Plk-2 inhibitors. By optimizing both the N-8 substituent and the biaryl region of the inh