Zobrazeno 1 - 10
of 464
pro vyhledávání: '"J. Fairweather"'
Publikováno v:
Frontiers in Earth Science, Vol 10 (2022)
Few studies in Australia have employed automated mineral techniques to augment archaeological site investigations, and there are no known published micromorphological studies of Australian shell midden sites. This pilot study presents results of a mi
Externí odkaz:
https://doaj.org/article/1e58fa29242f4f98babe25a2bea04af6
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 301 (2023)
Amino acid antiporters mediate the 1:1 exchange of groups of amino acids. Whether substrate specificity can be different for the inward and outward facing conformation has not been investigated systematically, although examples of asymmetric transpor
Externí odkaz:
https://doaj.org/article/74e5a6aa94fd491f93eac758699d657d
Autor:
Stephen J Fairweather, Esther Rajendran, Martin Blume, Kiran Javed, Birte Steinhöfel, Malcolm J McConville, Kiaran Kirk, Stefan Bröer, Giel G van Dooren
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009835 (2021)
Intracellular parasites of the phylum Apicomplexa are dependent on the scavenging of essential amino acids from their hosts. We previously identified a large family of apicomplexan-specific plasma membrane-localized amino acid transporters, the ApiAT
Externí odkaz:
https://doaj.org/article/53e61d32b3994dd4b73f4ec8560f0c98
Autor:
Stephen J. Fairweather, Shoko Okada, Gregory Gauthier-Coles, Kiran Javed, Angelika Bröer, Stefan Bröer
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Amino acid transporters play a vital role in metabolism and nutrient signaling pathways. Typically, transport activity is investigated using single substrates and competing amounts of other amino acids. We used GC-MS and LC-MS for metabolic screening
Externí odkaz:
https://doaj.org/article/0def0be3c75442ab837a5efc68a8c8be
Autor:
Keith A. Grimaldi, Ben van Ommen, Jose M. Ordovas, Laurence D. Parnell, John C. Mathers, Igor Bendik, Lorraine Brennan, Carlos Celis-Morales, Elisa Cirillo, Hannelore Daniel, Brenda de Kok, Ahmed El-Sohemy, Susan J. Fairweather-Tait, Rosalind Fallaize, Michael Fenech, Lynnette R. Ferguson, Eileen R. Gibney, Mike Gibney, Ingrid M. F. Gjelstad, Jim Kaput, Anette S. Karlsen, Silvia Kolossa, Julie Lovegrove, Anna L. Macready, Cyril F. M. Marsaux, J. Alfredo Martinez, Fermin Milagro, Santiago Navas-Carretero, Helen M. Roche, Wim H. M. Saris, Iwona Traczyk, Henk van Kranen, Lars Verschuren, Fabio Virgili, Peter Weber, Jildau Bouwman
Publikováno v:
Genes & Nutrition, Vol 12, Iss 1, Pp 1-12 (2017)
Abstract Nutrigenetic research examines the effects of inter-individual differences in genotype on responses to nutrients and other food components, in the context of health and of nutrient requirements. A practical application of nutrigenetics is th
Externí odkaz:
https://doaj.org/article/aa3141a2ce274460bca464949e891fc1
Autor:
Esther Rajendran, Sanduni V. Hapuarachchi, Catherine M. Miller, Stephen J. Fairweather, Yeping Cai, Nicholas C. Smith, Ian A. Cockburn, Stefan Bröer, Kiaran Kirk, Giel G. van Dooren
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Apicomplexans are parasites that use membrane transporters to scavenge essential nutrients from the host. Here the authors identify and characterize two apicomplexans transporters showing that these are crucial for cationic amino acid uptake, parasit
Externí odkaz:
https://doaj.org/article/af9f4f91b04841bdb2ffbb97deef1228
Autor:
Kathryn E R Parker, Stephen J Fairweather, Esther Rajendran, Martin Blume, Malcolm J McConville, Stefan Bröer, Kiaran Kirk, Giel G van Dooren
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007577 (2019)
Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized amino acid transport
Externí odkaz:
https://doaj.org/article/957920499bae44ad99b67c789c303b4e
Autor:
Vrinda Gupta, Megan L. O'Mara, Stephen J. Fairweather, Melissa H. Brown, Lauren N. Booth, Mohsen Chitsaz
Publikováno v:
ACS Infectious Diseases. 7:1833-1847
Multidrug resistance is a serious problem that threatens the effective treatment of the widespread sexually transmitted disease gonorrhea, caused by the Gram-negative bacterium Neisseria gonorrhoeae. The drug efflux pump primarily implicated in N. go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a0f2a860e4dffa18b107427656f9ae
https://doi.org/10.1021/acsinfecdis.1c00149
https://doi.org/10.1021/acsinfecdis.1c00149
Akademický článek
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Background and aim: The COVID-19 pandemic has severely affected the world’s population in the last two years. Along with non-pharmacological public health interventions, major efforts have also been made to identify effective drugs or active substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415a63d2a56a7b2b5f49094af4bea533
https://ueaeprints.uea.ac.uk/id/eprint/83575/
https://ueaeprints.uea.ac.uk/id/eprint/83575/
