Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J. F. Schildbach"'
Autor:
Robert E. Bruccoleri, P. D. Jeffrey, S. Sheriff, Michael N. Margolies, Richard I. Near, J. F. Schildbach, Jiri Novotny, Edgar Haber, Shi-Chung Ng
Publikováno v:
Journal of Biological Chemistry. 268:21739-21747
Antibody produced by a variant of the murine antidigoxin hybridoma 26-10 has reduced affinity for digoxin but enhanced recognition of the digoxin 12-hydroxyl due to a Tyr to His substitution at heavy chain position 50 (Schildbach, J. F., Panka, D. J.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1323ab6e0f10cd6b5cf74bf2aa919ab
https://doi.org/10.1016/s0021-9258(20)80605-x
https://doi.org/10.1016/s0021-9258(20)80605-x
Autor:
Gina C. Jager, Leonard A. Herzenberg, Robert E. Bruccoleri, Meredith Mudgett-Hunter, David J. Panka, David R. Parks, Michael N. Margolies, Jiri Novotny, E Haber, J. F. Schildbach
Publikováno v:
Journal of Biological Chemistry. 266:4640-4647
Two spontaneous variants of the murine anti-digoxin antibody-producing hybridoma cell line 26-10 were isolated by two-color fluorescence-activated cell sorting on the basis of altered hapten binding. The variable region sequences of the antibodies pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0e08eaa9d1ae8aca70f728e81d45a7
https://doi.org/10.1016/s0021-9258(20)64370-8
https://doi.org/10.1016/s0021-9258(20)64370-8
Autor:
J, Ping, J F, Schildbach, S Y, Shaw, T, Quertermous, J, Novotny, R, Bruccoleri, M N, Margolies
Publikováno v:
The Journal of biological chemistry. 268(31)
In certain instances, antibody variable region mutations outside of the antigen-combining site influence antigen binding. We reported previously that a heavy chain mutation (Ser-94--Arg) decreased binding of the anti-digoxin antibody 40-150, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bcc886c638cc363778763dc7d51c84e
https://pubmed.ncbi.nlm.nih.gov/8226814
https://pubmed.ncbi.nlm.nih.gov/8226814
Autor:
J F, Schildbach, D J, Panka, D R, Parks, G C, Jager, J, Novotny, L A, Herzenberg, M, Mudgett-Hunter, R E, Bruccoleri, E, Haber, M N, Margolies
Publikováno v:
The Journal of biological chemistry. 266(7)
Two spontaneous variants of the murine anti-digoxin antibody-producing hybridoma cell line 26-10 were isolated by two-color fluorescence-activated cell sorting on the basis of altered hapten binding. The variable region sequences of the antibodies pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a940e4eb84311fedb177342838824d8
https://pubmed.ncbi.nlm.nih.gov/1999439
https://pubmed.ncbi.nlm.nih.gov/1999439